Ca(2+)/calmodulin directly interacts with the pleckstrin homology domain of AKT1. (Q33288302)

25 July 2017

Ca(2+)/calmodulin directly interacts with the pleckstrin homology domain of AKT1. (English)

1 reference

Serine/threonine-protein kinase akt-1 CELE_C12D8.10

25 July 2017

1 reference

GOA release 2020-03-11

author name string

Biao Dong

series ordinal

1

1 reference

25 July 2017

C Alexander Valencia

series ordinal

2

1 reference

25 July 2017

Rihe Liu

series ordinal

3

1 reference

25 July 2017

language of work or name

English

0 references

publication date

19 June 2007

1 reference

Journal of Biological Chemistry

25 July 2017

1 reference

25 July 2017

282

1 reference

25 July 2017

34

1 reference

25 July 2017

25131-25140

1 reference

Calmodulin-mediated activation of Akt regulates survival of c-Myc-overexpressing mouse mammary carcinoma cells

25 July 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Scanning the human proteome for calmodulin-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

AH/PH domain-mediated interaction between Akt molecules and its potential role in Akt regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Isolation of transforming murine leukemia viruses from mice with a high incidence of spontaneous lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

AKT plays a central role in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

AKT crystal structure and AKT-specific inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

PI 3-kinase, Akt and cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Ten years of protein kinase B signalling: a hard Akt to follow

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Akt-dependent phosphorylation of p21(Cip1) regulates PCNA binding and proliferation of endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

The serpin alpha1-proteinase inhibitor is a critical substrate for gelatinase B/MMP-9 in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Direct control of the Forkhead transcription factor AFX by protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Regulation of cell death protease caspase-9 by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Induction of NF-kappaB by the Akt/PKB kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Unravelling the activation mechanisms of protein kinase B/Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Advances in protein kinase B signalling: AKTion on multiple fronts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Activation of AKT kinases in cancer: implications for therapeutic targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Apoptosis defects and chemotherapy resistance: molecular interaction maps and networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Targeting the PI3K-Akt pathway in human cancer: rationale and promise

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Lost in translation: dysregulation of cap-dependent translation and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

The Akt pathway: molecular targets for anti-cancer drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Perturbations of the AKT signaling pathway in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

AKT signaling in normal and malignant cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Regulation of the Akt kinase by interacting proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Calmodulin is a phospholipase C-beta interacting protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

High-resolution structure of the pleckstrin homology domain of protein kinase b/akt bound to phosphatidylinositol (3,4,5)-trisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Binding of phosphatidylinositol 3,4,5-trisphosphate to the pleckstrin homology domain of protein kinase B induces a conformational change

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Crystal structure of an activated Akt/protein kinase B ternary complex with GSK3-peptide and AMP-PNP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Solution structure and backbone dynamics of the pleckstrin homology domain of the human protein kinase B (PKB/Akt). Interaction with inositol phosphates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Ca(2+)-binding and structural dynamics in the functions of calmodulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Molecular and structural basis of target recognition by calmodulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

CALMODULIN AND CALMODULIN-BINDING PROTEINS IN PLANTS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Calmodulin: a prototypical calcium sensor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Calmodulin as an ion channel subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Calcium/calmodulin-mediated signal network in plants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Pleckstrin homology domains and the cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

PTEN and myotubularin: novel phosphoinositide phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Mitogenic activation, phosphorylation, and nuclear translocation of protein kinase Bbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Regulation of protein kinase B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Role of translocation in the activation and function of protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Specificity and promiscuity in phosphoinositide binding by pleckstrin homology domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Specific binding of the Akt-1 protein kinase to phosphatidylinositol 3,4,5-trisphosphate without subsequent activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

Calmodulin target database

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702123200

21 January 2018

Identifiers

DOI

10.1074/JBC.M702123200

1 reference

25 July 2017

1 reference