Serine/threonine-protein kinase akt-1 CELE_C12D8.10 (Q29808395)

protein serine/threonine kinase activity

3 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q17941&geneProductId=UniProtKB:Q17941

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q17941&geneProductId=UniProtKB:Q17941

21 June 2018

Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q17941&geneProductId=UniProtKB:Q17941

4 references

1 January 2018

C. elegans SGK-1 is the critical component in the Akt/PKB kinase complex to control stress response and life span

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

1 January 2018

Spindle assembly checkpoint gene mdf-1 regulates germ cell proliferation in response to nutrition signals in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

1 January 2018

Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

1 January 2018

A PP2A regulatory subunit regulates C. elegans insulin/IGF-1 signaling by modulating AKT-1 phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

3 references

1 January 2018

Ca(2+)/Calmodulin-binding proteins from the C. elegans proteome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

1 January 2018

Ca(2+)/calmodulin directly interacts with the pleckstrin homology domain of AKT1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

2 references

phosphatidylinositol-3,4,5-trisphosphate binding

1 reference

1 January 2018

Caspase-activated phosphoinositide binding by CNT-1 promotes apoptosis by inhibiting the AKT pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

protein serine/threonine kinase activity

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

1 January 2018

Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

intracellular anatomical structure

IBA

cell component

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q17941&geneProductId=UniProtKB:Q17941

cytoplasmic side of plasma membrane

IBA

1 reference

1 January 2018

Caspase-activated phosphoinositide binding by CNT-1 promotes apoptosis by inhibiting the AKT pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

1 reference

1 January 2018

Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

1 reference

1 January 2018

Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

1 reference

1 January 2018

Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

intracellular anatomical structure

IDA

1 reference

10 September 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q17941&geneProductId=UniProtKB:Q17941

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

biological process

immune system process

1 reference

1 January 2018

1 reference

1 January 2018

Reversal of salt preference is directed by the insulin/PI3K and Gq/PKC signaling in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

multicellular organism development

IGI

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

Reversal of salt preference is directed by the insulin/PI3K and Gq/PKC signaling in Caenorhabditis elegans

chemosensory behavior

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

insulin receptor signaling pathway

IGI

1 reference

1 January 2018

Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination of adult lifespan

IMP

1 reference

1 January 2018

Mechanisms of life span determination in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

regulation of synaptic assembly at neuromuscular junction

IMP

1 reference

1 January 2018

Attenuation of insulin signalling contributes to FSN-1-mediated regulation of synapse development.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

peptidyl-serine phosphorylation

1 reference

21 June 2018

Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q17941&geneProductId=UniProtKB:Q17941

peptidyl-threonine phosphorylation

IDA

1 reference

1 January 2018

Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

IDA

1 reference

1 January 2018

AKT-1 regulates DNA-damage-induced germline apoptosis in C. elegans.

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

IMP

innate immune response

1 reference

1 January 2018

1 reference

1 January 2018

Reversal of salt preference is directed by the insulin/PI3K and Gq/PKC signaling in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

protein kinase B signaling

IGI

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

intracellular signal transduction

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941