Regulation of nuclear import and export by the GTPase Ran. (Q30309361)

16 June 2017

1 reference

title

Regulation of nuclear import and export by the GTPase Ran. (English)

1 reference

16 June 2017

Susanne M Steggerda

1

1 reference

PubMed ID

12019565

16 June 2017

Bryce M Paschal

series ordinal

2

1 reference

16 June 2017

1 January 2002

1 reference

International Review of Cytology

16 June 2017

1 reference

16 June 2017

217

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16 June 2017

41-91

1 reference

Higher order chromosome structure is affected by cold-sensitive mutations in a Schizosaccharomyces pombe gene crm1+ which encodes a 115-kD protein preferentially localized in the nucleus and its periphery

16 June 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Identification of cytosolic factors required for nuclear location sequence-mediated binding to the nuclear envelope

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Cytosolic proteins that specifically bind nuclear location signals are receptors for nuclear import

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

A yeast mutant, PRP20, altered in mRNA metabolism and maintenance of the nuclear structure, is defective in a gene homologous to the human gene RCC1 which is involved in the control of chromosome condensation

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Kap104p: a karyopherin involved in the nuclear transport of messenger RNA binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Architecture of the Xenopus nuclear pore complex revealed by three-dimensional cryo-electron microscopy.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Nuclear PRP20 protein is required for mRNA export

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

NAB2: a yeast nuclear polyadenylated RNA-binding protein essential for cell viability

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Identification of a nuclear export receptor for tRNA

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

The role of exportin-t in selective nuclear export of mature tRNAs

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

The role of Ran in nuclear function.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Model of the ran-RCC1 interaction using biochemical and docking experiments

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

1 reference

7 January 2021

Structural basis for the interaction between FxFG nucleoporin repeats and importin-beta in nuclear trafficking

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Interaction between NTF2 and xFxFG-containing nucleoporins is required to mediate nuclear import of RanGDP

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

RNA1 encodes a GTPase-activating protein specific for Gsp1p, the Ran/TC4 homologue of Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

GSP1 and GSP2, genetic suppressors of the prp20-1 mutant in Saccharomyces cerevisiae: GTP-binding proteins involved in the maintenance of nuclear organization

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

RanBP1 is crucial for the release of RanGTP from importin β-related nuclear transport factors

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Co-activation of RanGTPase and inhibition of GTP dissociation by Ran-GTP binding protein RanBP1

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

NXT1 is necessary for the terminal step of Crm1-mediated nuclear export

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

DNA binding domains in diverse nuclear receptors function as nuclear export signals.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Identification of an NTF2-related factor that binds Ran-GTP and regulates nuclear protein export.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Definition of a consensus transportin-specific nucleocytoplasmic transport signal

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

The 1.6 angstroms resolution crystal structure of nuclear transport factor 2 (NTF2)

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

A specific subset of SR proteins shuttles continuously between the nucleus and the cytoplasm

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Dissecting the interactions between NTF2, RanGDP, and the nucleoporin XFXFG repeats

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Diverse effects of the guanine nucleotide exchange factor RCC1 on RNA transport

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Different binding domains for Ran-GTP and Ran-GDP/RanBP1 on nuclear import factor p97

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Sequence and characterization of cytoplasmic nuclear protein import factor p97

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

RanBP1 stabilizes the interaction of Ran with p97 nuclear protein import

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Structure of the nuclear transport complex karyopherin-beta2-Ran x GppNHp

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Structure of importin-beta bound to the IBB domain of importin-alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Separate binding sites on nuclear transport factor 2 (NTF2) for GDP-Ran and the phenylalanine-rich repeat regions of nucleoporins p62 and Nsp1p

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Rna1p, a Ran/TC4 GTPase activating protein, is required for nuclear import

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

The NTF2 gene encodes an essential, highly conserved protein that functions in nuclear transport in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Characterization of proteins that interact with the cell-cycle regulatory protein Ran/TC4

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Running on Ran: nuclear transport and the mitotic spindle.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Identification and characterization of a nuclear pore complex protein

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

A murine homolog of the yeast RNA1 gene is required for postimplantation development.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

RanGTP targets p97 to RanBP2, a filamentous protein localized at the cytoplasmic periphery of the nuclear pore complex

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Nuclear targeting sequences--a consensus?

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

A polypeptide domain that specifies migration of nucleoplasmin into the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Genetic approaches to nuclear pore structure and function.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

hnRNP proteins and the biogenesis of mRNA

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Receptor-mediated substrate translocation through the nuclear pore complex without nucleotide triphosphate hydrolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Movement of a karyophilic protein through the nuclear pores of oocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Inhibition of in vitro nuclear transport by a lectin that binds to nuclear pores

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Diversity in the signals required for nuclear accumulation of U snRNPs and variety in the pathways of nuclear transport

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Nuclear transport of U1 snRNP in somatic cells: differences in signal requirement compared with Xenopus laevis oocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Evidence that HIV-1 Rev directly promotes the nuclear export of unspliced RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

The nuclear transport factor karyopherin beta binds stoichiometrically to Ran-GTP and inhibits the Ran GTPase activating protein

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Disassembly of RanGTP-karyopherin beta complex, an intermediate in nuclear protein import.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Structural basis of recognition of monopartite and bipartite nuclear localization sequences by mammalian importin-alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

CRM1 is an export receptor for leucine-rich nuclear export signals

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

CRM1 is responsible for intracellular transport mediated by the nuclear export signal

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Functional organization of the nuclear envelope

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Synthetic peptides as nuclear localization signals

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

A novel class of RanGTP binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

A 41 amino acid motif in importin-alpha confers binding to importin-beta and hence transit into the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Two different subunits of importin cooperate to recognize nuclear localization signals and bind them to the nuclear envelope

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Isolation of a protein that is essential for the first step of nuclear protein import

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Distinct functions for the two importin subunits in nuclear protein import

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Topological characteristics of helical repeat proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

NXT1 (p15) is a crucial cellular cofactor in TAP-dependent export of intron-containing RNA in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Conserved charged residues in the leucine-rich repeat domain of the Ran GTPase activating protein are required for Ran binding and GTPase activation

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

RanBP1, a Ras-like nuclear G protein binding to Ran/TC4, inhibits RCC1 via Ran/TC4

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Determination of the functional domain organization of the importin alpha nuclear import factor

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

The Crystal Structure of rna1p

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Architecture and design of the nuclear pore complex

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Evolution and function of ubiquitin-like protein-conjugation systems

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Calreticulin Is a receptor for nuclear export

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Nuclear pore complex glycoproteins contain cytoplasmically disposed O-linked N-acetylglucosamine

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Cse1p is required for export of Srp1p/importin-alpha from the nucleus in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

A yeast mutant which accumulates precursor tRNAs

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Processing of intervening sequences: a new yeast mutant which fails to excise intervening sequences from precursor tRNAs

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

The yeast RNA1 gene product necessary for RNA processing is located in the cytosol and apparently excluded from the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Snurportin1, an m3G-cap-specific nuclear import receptor with a novel domain structure

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Cloning and characterization of LOS1, a Saccharomyces cerevisiae gene that affects tRNA splicing

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

The nuclear pore-targeting complex binds to nuclear pores after association with a karyophile.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

A karyophilic protein forms a stable complex with cytoplasmic components prior to nuclear pore binding

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

The GLFG repetitive region of the nucleoporin Nup116p interacts with Kap95p, an essential yeast nuclear import factor

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

A cap-binding protein complex mediating U snRNA export

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Nuclear export of different classes of RNA is mediated by specific factors

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Beyond nuclear transport. Ran-GTP as a determinant of spindle assembly

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Sequence requirements for nuclear location of simian virus 40 large-T antigen

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

A short amino acid sequence able to specify nuclear location

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Structure and assembly of the spliceosomal small nuclear ribonucleoprotein particles

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

The Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to human

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Transportin-SR, a nuclear import receptor for SR proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

A role for RanBP1 in the release of CRM1 from the nuclear pore complex in a terminal step of nuclear export

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Interaction of the nuclear GTP-binding protein Ran with its regulatory proteins RCC1 and RanGAP1

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

The Kinetic Mechanism of Ran-Nucleotide Exchange Catalyzed by RCC1

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Autoinhibition by an internal nuclear localization signal revealed by the crystal structure of mammalian importin alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

1 reference

7 January 2021

Cloning of two novel human importin-alpha subunits and analysis of the expression pattern of the importin-alpha protein family

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Evidence for distinct substrate specificities of importin alpha family members in nuclear protein import

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Ran-unassisted nuclear migration of a 97-kD component of nuclear pore-targeting complex

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Yeast Ran-binding protein 1 (Yrb1) shuttles between the nucleus and cytoplasm and is exported from the nucleus via a CRM1 (XPO1)-dependent pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Cse1p functions as the nuclear export receptor for importin alpha in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Export of importin alpha from the nucleus is mediated by a specific nuclear transport factor

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Dominant-negative mutants of importin-beta block multiple pathways of import and export through the nuclear pore complex

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Identification of a tRNA-specific nuclear export receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

A human importin-beta family protein, transportin-SR2, interacts with the phosphorylated RS domain of SR proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Selective disruption of nuclear import by a functional mutant nuclear transport carrier

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Construction and characterization of an SV40 mutant defective in nuclear transport of T antigen.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Induction of nuclear transport with a synthetic peptide homologous to the SV40 T antigen transport signal

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Modification of Ran GTPase-activating protein by the small ubiquitin-related modifier SUMO-1 requires Ubc9, an E2-type ubiquitin-conjugating enzyme homologue

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Arginine/serine-rich domains of the su(wa) and tra RNA processing regulators target proteins to a subnuclear compartment implicated in splicing

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Ran-binding protein 3 is a cofactor for Crm1-mediated nuclear protein export

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

NUP2, a novel yeast nucleoporin, has functional overlap with other proteins of the nuclear pore complex

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Ran-binding protein 1 (RanBP1) forms a ternary complex with Ran and karyopherin beta and reduces Ran GTPase-activating protein (RanGAP) inhibition by karyopherin beta

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Mutations within the Ran/TC4 GTPase. Effects on regulatory factor interactions and subcellular localization

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Ran binding domains promote the interaction of Ran with p97/beta-karyopherin, linking the docking and translocation steps of nuclear import

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Nuclear transport: randy couples

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

The ras superfamily of molecular switches

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Molecular characterization of the SUMO-1 modification of RanGAP1 and its role in nuclear envelope association

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Identification and characterization of the human MOG1 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Premature initiation of mitosis in yeast lacking RCC1 or an interacting GTPase

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

SUMO-1 modification and its role in targeting the Ran GTPase-activating protein, RanGAP1, to the nuclear pore complex

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

SUMO--nonclassical ubiquitin

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Inhibition of nuclear protein import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

A functional homologue of the RNA1 gene product in Schizosaccharomyces pombe: purification, biochemical characterization, and identification of a leucine-rich repeat motif

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Calreticulin is essential for cardiac development

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

A nuclear export signal in hnRNP A1: a signal-mediated, temperature-dependent nuclear protein export pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

The K nuclear shuttling domain: a novel signal for nuclear import and nuclear export in the hnRNP K protein

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

The GTP-binding protein Ran/TC4 is required for protein import into the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Human RanBP3, a group of nuclear RanGTP binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Nuclear export of proteins and RNAs

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Transport of proteins and RNAs in and out of the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Transportin: nuclear transport receptor of a novel nuclear protein import pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Role of the nuclear transport factor p10 in nuclear import.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Nuclear import of the ran exchange factor, RCC1, is mediated by at least two distinct mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Chromatin docking and exchange activity enhancement of RCC1 by histones H2A and H2B

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

The importin-beta family member Crm1p bridges the interaction between Rev and the nuclear pore complex during nuclear export

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

An N-ethylmaleimide-sensitive cytosolic factor necessary for nuclear protein import: requirement in signal-mediated binding to the nuclear pore

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Nuclear import can be separated into distinct steps in vitro: nuclear pore binding and translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Loss of RCC1, a nuclear DNA-binding protein, uncouples the completion of DNA replication from the activation of cdc2 protein kinase and mitosis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Yrb2p, a Nup2p-related yeast protein, has a functional overlap with Rna1p, a yeast Ran-GTPase-activating protein

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

PHAX, a mediator of U snRNA nuclear export whose activity is regulated by phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Isolation and characterization of the active cDNA of the human cell cycle gene (RCC1) involved in the regulation of onset of chromosome condensation

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

The RCC1 protein, a regulator for the onset of chromosome condensation locates in the nucleus and binds to DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Yrb1p interaction with the gsp1p C terminus blocks Mog1p stimulation of GTP release from Gsp1p

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Evidence for a role of CRM1 in signal-mediated nuclear protein export

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Domains of Crm1 involved in the formation of the Crm1, RanGTP, and leucine-rich nuclear export sequences trimeric complex

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

RanGTP-binding protein NXT1 facilitates nuclear export of different classes of RNA in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Nuclear import of U snRNPs requires importin beta

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Molecular dissection of the nuclear pore complex

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

CRM1-mediated recycling of snurportin 1 to the cytoplasm

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

High levels of the GTPase Ran/TC4 relieve the requirement for nuclear protein transport factor 2.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Transport routes through the nuclear pore complex.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

A distinct and parallel pathway for the nuclear import of an mRNA-binding protein

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Facilitated nucleocytoplasmic shuttling of the Ran binding protein RanBP1

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

THE HIV-1 REV PROTEIN

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

A novel receptor-mediated nuclear protein import pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

The balance of RanBP1 and RCC1 is critical for nuclear assembly and nuclear transport

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

The mechanism of ran import into the nucleus by nuclear transport factor 2.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Effects of mutant Ran/TC4 proteins on cell cycle progression.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Ran/TC4: a small nuclear GTP-binding protein that regulates DNA synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Structural basis for guanine nucleotide exchange on Ran by the regulator of chromosome condensation (RCC1)

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

The 1.7 A crystal structure of the regulator of chromosome condensation (RCC1) reveals a seven-bladed propeller

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors, and nucleoporins

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

The translocation of transportin–cargo complexes through nuclear pores is independent of both Ran and energy

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

NTF2 mediates nuclear import of Ran.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Requirement of guanosine triphosphate-bound ran for signal-mediated nuclear protein export

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

A nuclear export signal is essential for the cytosolic localization of the Ran binding protein, RanBP1.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

The C terminus of the nuclear RAN/TC4 GTPase stabilizes the GDP-bound state and mediates interactions with RCC1, RAN-GAP, and HTF9A/RANBP1

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Nuclear protein migration involves two steps: rapid binding at the nuclear envelope followed by slower translocation through nuclear pores

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: identification of a class of bipartite nuclear targeting sequence

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

The yeast nuclear pore complex: composition, architecture, and transport mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

The nuclear pore complex: a protein machine bridging the nucleus and cytoplasm

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Direct and indirect association of the small GTPase ran with nuclear pore proteins and soluble transport factors: studies in Xenopus laevis egg extracts.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

The RCC1 protein interacts with Ran, RanBP1, hsc70, and a 340-kDa protein in Xenopus extracts.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Ubc9p and the conjugation of SUMO-1 to RanGAP1 and RanBP2.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Nuclear mRNA export requires complex formation between Mex67p and Mtr2p at the nuclear pores.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

GTPase-activating proteins: helping hands to complement an active site.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Crystal structure of the nuclear Ras-related protein Ran in its GDP-bound form.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Mtr10p functions as a nuclear import receptor for the mRNA-binding protein Npl3p

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

A nuclear localization domain in the hnRNP A1 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Nuclear import of Ran is mediated by the transport factor NTF2.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Monoclonal antibodies identify a group of nuclear pore complex glycoproteins

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Cse1p is involved in export of yeast importin alpha from the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Nup2p, a yeast nucleoporin, functions in bidirectional transport of importin alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Invasion of the nucleotide snatchers: structural insights into the mechanism of G protein GEFs

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Exportin 1 (Crm1p) is an essential nuclear export factor

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Monoclonal antibodies to NTF2 inhibit nuclear protein import by preventing nuclear translocation of the GTPase Ran

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

The mammalian Mog1 protein is a guanine nucleotide release factor for Ran

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Identification of a conserved loop in Mog1 that releases GTP from Ran.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

O-linked glycoproteins of the nuclear pore complex interact with a cytosolic factor required for nuclear protein import

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

1.9 A resolution crystal structure of the Saccharomyces cerevisiae Ran-binding protein Mog1p

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Structural basis for molecular recognition between nuclear transport factor 2 (NTF2) and the GDP-bound form of the Ras-family GTPase Ran

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

The nuclear pore complex: from molecular architecture to functional dynamics

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Yrb2p is a nuclear protein that interacts with Prp20p, a yeast Rcc1 homologue

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Structural view of the Ran-Importin beta interaction at 2.3 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Structure of a Ran-binding domain complexed with Ran bound to a GTP analogue: implications for nuclear transport

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Different Structural and Kinetic Requirements for the Interaction of Ran with the Ran-Binding Domains from RanBP2 and Importin-β

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Identification of hSRP1 alpha as a functional receptor for nuclear localization sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

RanBP3 contains an unusual nuclear localization signal that is imported preferentially by importin-alpha3.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Identification of a signal for rapid export of proteins from the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Leptomycin B is an inhibitor of nuclear export: inhibition of nucleo-cytoplasmic translocation of the human immunodeficiency virus type 1 (HIV-1) Rev protein and Rev-dependent mRNA

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Interaction between the small GTPase Ran/Gsp1p and Ntf2p is required for nuclear transport

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Nup358, a cytoplasmically exposed nucleoporin with peptide repeats, Ran-GTP binding sites, zinc fingers, a cyclophilin A homologous domain, and a leucine-rich region

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

CSE1 and CSE2, two new genes required for accurate mitotic chromosome segregation in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Cloning and characterization of SRP1, a suppressor of temperature-sensitive RNA polymerase I mutations, in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

GTP hydrolysis links initiation and termination of nuclear import on the nucleoporin nup358

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

A giant nucleopore protein that binds Ran/TC4

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Nuclear export of mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Variants of defective simian papovavirus 40 (PARA) characterized by cytoplasmic localization of simian papovavirus 40 tumor antigen.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Temperature-sensitive Yeast Mutant Defective in Ribonucleic Acid Production

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Nuclear transport of human immunodeficiency virus type 1, visna virus, and equine infectious anemia virus Rev proteins: identification of a family of transferable nuclear export signals.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

Exploring nuclear pore complex structure and function in molecular detail.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2802%2917012-4

7 January 2021

10.1016/S0074-7696(02)17012-4

Identifiers

DOI

1 reference

16 June 2017

1 reference

PubMed ID

12019565