Export of importin alpha from the nucleus is mediated by a specific nuclear transport factor (Q24316152)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0042564

Chromosome segregation 1 like

1 reference

GOA release 2020-03-11

D Görlich

5

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author name string

U Kutay

1

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F R Bischoff

2

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S Kostka

3

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R Kraft

Cytosolic proteins that specifically bind nuclear location signals are receptors for nuclear import

4

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publication date

19 September 1997

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language of work or name

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90

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issue

6

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page(s)

1061-71

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cites work

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7 January 2021

Kap104p: a karyopherin involved in the nuclear transport of messenger RNA binding proteins

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7 January 2021

RNA1 encodes a GTPase-activating protein specific for Gsp1p, the Ran/TC4 homologue of Saccharomyces cerevisiae

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7 January 2021

RanGAP1 induces GTPase activity of nuclear Ras-related Ran

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7 January 2021

Human RanGTPase-activating protein RanGAP1 is a homologue of yeast Rna1p involved in mRNA processing and transport

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7 January 2021

Co-activation of RanGTPase and inhibition of GTP dissociation by Ran-GTP binding protein RanBP1

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7 January 2021

Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1

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7 January 2021

Mitotic regulator protein RCC1 is complexed with a nuclear ras-related polypeptide

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7 January 2021

Cloning and characterization of a cellular apoptosis susceptibility gene, the human homologue to the yeast chromosome segregation gene CSE1

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7 January 2021

Role of CAS, a human homologue to the yeast chromosome segregation gene CSE1, in toxin and tumor necrosis factor mediated apoptosis

1 reference

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7 January 2021

RanBP1 stabilizes the interaction of Ran with p97 nuclear protein import

1 reference

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7 January 2021

Rna1p, a Ran/TC4 GTPase activating protein, is required for nuclear import

1 reference

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7 January 2021

Characterization of proteins that interact with the cell-cycle regulatory protein Ran/TC4

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7 January 2021

Nuclear targeting sequences--a consensus?

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7 January 2021

Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line

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The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs

1 reference

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7 January 2021

The nuclear transport factor karyopherin beta binds stoichiometrically to Ran-GTP and inhibits the Ran GTPase activating protein

1 reference

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7 January 2021

The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88

1 reference

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7 January 2021

CRM1 is an export receptor for leucine-rich nuclear export signals

1 reference

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7 January 2021

Amphibian transcription factor IIIA proteins contain a sequence element functionally equivalent to the nuclear export signal of human immunodeficiency virus type 1 Rev

1 reference

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7 January 2021

Nuclear protein import

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980372-4

7 January 2021

Two different subunits of importin cooperate to recognize nuclear localization signals and bind them to the nuclear envelope

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7 January 2021

Distinct functions for the two importin subunits in nuclear protein import

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7 January 2021

A 41 amino acid motif in importin-alpha confers binding to importin-beta and hence transit into the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980372-4

7 January 2021

Importin provides a link between nuclear protein import and U snRNA export

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980372-4

7 January 2021

A novel class of RanGTP binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980372-4

7 January 2021

The yeast RNA1 gene product necessary for RNA processing is located in the cytosol and apparently excluded from the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980372-4

7 January 2021

Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980372-4

7 January 2021

Interaction of the nuclear GTP-binding protein Ran with its regulatory proteins RCC1 and RanGAP1

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980372-4

7 January 2021

A GTPase controlling nuclear trafficking: running the right way or walking RANdomly?

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980372-4

7 January 2021

Dynamic localization of the nuclear import receptor and its interactions with transport factors

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980372-4

7 January 2021

Dominant-negative mutants of importin-beta block multiple pathways of import and export through the nuclear pore complex

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980372-4

7 January 2021

The yeast nuclear import receptor is required for mitosis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980372-4

7 January 2021

Ran-binding protein 1 (RanBP1) forms a ternary complex with Ran and karyopherin beta and reduces Ran GTPase-activating protein (RanGAP) inhibition by karyopherin beta

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980372-4

7 January 2021

A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980372-4

7 January 2021

A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980372-4

7 January 2021

Inhibition of nuclear protein import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor

1 reference

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7 January 2021

A functional homologue of the RNA1 gene product in Schizosaccharomyces pombe: purification, biochemical characterization, and identification of a leucine-rich repeat motif

1 reference

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7 January 2021

A nuclear export signal in hnRNP A1: a signal-mediated, temperature-dependent nuclear protein export pathway

1 reference

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7 January 2021

The K nuclear shuttling domain: a novel signal for nuclear import and nuclear export in the hnRNP K protein

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980372-4

7 January 2021

The GTP-binding protein Ran/TC4 is required for protein import into the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980372-4

7 January 2021

Purification of a Ran-interacting protein that is required for protein import into the nucleus

1 reference

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7 January 2021

Mammalian karyopherin alpha 1 beta and alpha 2 beta heterodimers: alpha 1 or alpha 2 subunit binds nuclear localization signal and beta subunit interacts with peptide repeat-containing nucleoporins

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7 January 2021

Transportin: nuclear transport receptor of a novel nuclear protein import pathway

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7 January 2021

Nucleocytoplasmic transport: signals, mechanisms and regulation

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7 January 2021

The RCC1 protein, a regulator for the onset of chromosome condensation locates in the nucleus and binds to DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980372-4

7 January 2021

RAN/TC4 mutants identify a common requirement for snRNP and protein import into the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980372-4

7 January 2021

A novel receptor-mediated nuclear protein import pathway

1 reference

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7 January 2021

Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors, and nucleoporins

1 reference

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7 January 2021

Requirement of guanosine triphosphate-bound ran for signal-mediated nuclear protein export

1 reference

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7 January 2021

A nuclear export signal is essential for the cytosolic localization of the Ran binding protein, RanBP1.

1 reference

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7 January 2021

The C terminus of the nuclear RAN/TC4 GTPase stabilizes the GDP-bound state and mediates interactions with RCC1, RAN-GAP, and HTF9A/RANBP1

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980372-4

7 January 2021

Protein import into the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980372-4

7 January 2021

The GTP-bound form of the yeast Ran/TC4 homologue blocks nuclear protein import and appearance of poly(A)+ RNA in the cytoplasm

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980372-4

7 January 2021

In vivo nuclear transport kinetics in Saccharomyces cerevisiae: a role for heat shock protein 70 during targeting and translocation

1 reference

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7 January 2021

A nuclear localization domain in the hnRNP A1 protein

1 reference

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7 January 2021

Exportin 1 (Crm1p) is an essential nuclear export factor

1 reference

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7 January 2021

Identification of hSRP1 alpha as a functional receptor for nuclear localization sequences

1 reference

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7 January 2021

The conserved amino-terminal domain of hSRP1 alpha is essential for nuclear protein import

1 reference

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7 January 2021

Characterization of the nuclear protein import mechanism using Ran mutants with altered nucleotide binding specificities

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980372-4

7 January 2021

Identification of a signal for rapid export of proteins from the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980372-4

7 January 2021

Nup358, a cytoplasmically exposed nucleoporin with peptide repeats, Ran-GTP binding sites, zinc fingers, a cyclophilin A homologous domain, and a leucine-rich region

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980372-4

7 January 2021

CSE1 and CSE2, two new genes required for accurate mitotic chromosome segregation in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980372-4

7 January 2021

Cloning and characterization of SRP1, a suppressor of temperature-sensitive RNA polymerase I mutations, in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980372-4

7 January 2021

A giant nucleopore protein that binds Ran/TC4

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980372-4

7 January 2021