Focal adhesion kinase: in command and control of cell motility (Q29615192)

Europe PubMed Central

title

Focal adhesion kinase: in command and control of cell motility (English)

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30 April 2017

author name string

Mitra SK

series ordinal

1

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30 April 2017

Hanson DA

series ordinal

2

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30 April 2017

Schlaepfer DD

series ordinal

3

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15688067

30 April 2017

language of work or name

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30 April 2017

publication date

January 2005

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Nature Reviews Molecular Cell Biology

30 April 2017

published in

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30 April 2017

volume

6

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issue

1

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page(s)

56-68

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The integrin-actin connection, an eternal love affair

30 April 2017

cites work

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Cell migration: integrating signals from front to back

1 May 2017

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Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

1 May 2017

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FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly

1 May 2017

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Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses

1 May 2017

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Focal adhesion kinase is required for blood vessel morphogenesis

1 May 2017

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Differential regulation of cell motility and invasion by FAK

1 May 2017

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FAK integrates growth-factor and integrin signals to promote cell migration

1 May 2017

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Regulation of the PH-domain-containing tyrosine kinase Etk by focal adhesion kinase through the FERM domain

1 May 2017

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PIAS1-mediated sumoylation of focal adhesion kinase activates its autophosphorylation

1 May 2017

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Identification of transcription factor KLF8 as a downstream target of focal adhesion kinase in its regulation of cyclin D1 and cell cycle progression

1 May 2017

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Biochemical signals and biological responses elicited by the focal adhesion kinase

1 May 2017

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Alternative splicing controls the mechanisms of FAK autophosphorylation

1 May 2017

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Structures of the cancer-related Aurora-A, FAK, and EphA2 protein kinases from nanovolume crystallography

1 May 2017

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Regulation of focal adhesion kinase by a novel protein inhibitor FIP200

1 May 2017

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Src kinase activation by direct interaction with the integrin β cytoplasmic domain

1 May 2017

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Paxillin and focal adhesion signalling

1 May 2017

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The focal adhesion targeting (FAT) region of focal adhesion kinase is a four-helix bundle that binds paxillin

1 May 2017

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Structural insight into the mechanisms of targeting and signaling of focal adhesion kinase

1 May 2017

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Phosphorylation-dependent paxillin-ERK association mediates hepatocyte growth factor-stimulated epithelial morphogenesis

1 May 2017

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Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry

1 May 2017

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Overexpression of FAK promotes Ras activity through the formation of a FAK/p120RasGAP complex in malignant astrocytoma cells

1 May 2017

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Control of axonal branching and synapse formation by focal adhesion kinase

1 May 2017

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Focal adhesion kinase regulation of N-WASP subcellular localization and function

1 May 2017

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mDia mediates Rho-regulated formation and orientation of stable microtubules

1 May 2017

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PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation

1 May 2017

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Serine 732 phosphorylation of FAK by Cdk5 is important for microtubule organization, nuclear movement, and neuronal migration

1 May 2017

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Pyk2 and FAK regulate neurite outgrowth induced by growth factors and integrins

1 May 2017

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Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle

1 May 2017

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Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin

1 May 2017

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Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions

1 May 2017

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FAK deficiency in cells contributing to the basal lamina results in cortical abnormalities resembling congenital muscular dystrophies

1 May 2017

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Taking cell-matrix adhesions to the third dimension

1 May 2017

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Focal adhesion kinase is upstream of phosphatidylinositol 3-kinase/Akt in regulating fibroblast survival in response to contraction of type I collagen matrices via a beta 1 integrin viability signaling pathway

1 May 2017

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Differential regulation of Pyk2 and focal adhesion kinase (FAK). The C-terminal domain of FAK confers response to cell adhesion

1 May 2017

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Regulation of the formation of osteoclastic actin rings by proline-rich tyrosine kinase 2 interacting with gelsolin

1 May 2017

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Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration

1 May 2017

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Pyk2 regulates multiple signaling events crucial for macrophage morphology and migration

1 May 2017

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Absence of marginal zone B cells in Pyk-2-deficient mice defines their role in the humoral response

1 May 2017

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Cardiovascular anomaly, impaired actin bundling and resistance to Src-induced transformation in mice lacking p130Cas

1 May 2017

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Src family kinases are required for integrin but not PDGFR signal transduction.

1 May 2017

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Integrin signaling to the actin cytoskeleton.

1 May 2017

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Focal adhesion kinase: the first ten years

31 March 2020

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Localized stabilization of microtubules by integrin- and FAK-facilitated Rho signaling

31 March 2020

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Increased dosage and amplification of the focal adhesion kinase gene in human cancer cells.

31 March 2020

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Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling

31 March 2020

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v-Src SH3-enhanced interaction with focal adhesion kinase at beta 1 integrin-containing invadopodia promotes cell invasion

31 March 2020

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FRNK blocks v-Src-stimulated invasion and experimental metastases without effects on cell motility or growth

31 March 2020

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Control of motile and invasive cell phenotypes by focal adhesion kinase.

31 March 2020

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Roles played by a subset of integrin signaling molecules in cadherin-based cell-cell adhesion

31 March 2020

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Integrins in mechanotransduction

31 March 2020

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A novel role for FAK as a protease-targeting adaptor protein: regulation by p42 ERK and Src.

31 March 2020

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Human Cytomegalovirus Chemokine Receptor US28-induced Smooth Muscle Cell Migration Is Mediated by Focal Adhesion Kinase and Src

31 March 2020

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Ezrin interacts with focal adhesion kinase and induces its activation independently of cell-matrix adhesion

31 March 2020

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Nuclear import of N-terminal FAK by activation of the FcepsilonRI receptor in RBL-2H3 cells

31 March 2020

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FAK induces expression of Prx1 to promote tenascin-C-dependent fibroblast migration.

31 March 2020

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Focal adhesion kinase signaling activities and their implications in the control of cell survival and motility

31 March 2020

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Regulation of integrin-mediated cellular responses through assembly of a CAS/Crk scaffold.

31 March 2020

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Direct Interaction of Focal Adhesion Kinase with p190RhoGEF

31 March 2020

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Negative regulation of FAK signaling by SOCS proteins

31 March 2020

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RAFTK/Pyk2-mediated cellular signalling

31 March 2020

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Targeting Pyk2 to beta 1-integrin-containing focal contacts rescues fibronectin-stimulated signaling and haptotactic motility defects of focal adhesion kinase-null cells

31 March 2020

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Phosphorylation of focal adhesion kinase at tyrosine 861 is crucial for Ras transformation of fibroblasts

31 March 2020

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Characterization of an activated mutant of focal adhesion kinase: 'SuperFAK'

31 March 2020

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Signaling between focal adhesion kinase and trio

31 March 2020

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Regulation of focal adhesion kinase by its amino-terminal domain through an autoinhibitory interaction

31 March 2020

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PTP alpha regulates integrin-stimulated FAK autophosphorylation and cytoskeletal rearrangement in cell spreading and migration

31 March 2020

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Reactive oxygen species as essential mediators of cell adhesion: the oxidative inhibition of a FAK tyrosine phosphatase is required for cell adhesion.

31 March 2020

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Purification of pseudopodia from polarized cells reveals redistribution and activation of Rac through assembly of a CAS/Crk scaffold

31 March 2020

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CAS promotes invasiveness of Src-transformed cells

31 March 2020

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Paxillin: a focal adhesion-associated adaptor protein

31 March 2020

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Vinculin modulation of paxillin-FAK interactions regulates ERK to control survival and motility.

31 March 2020

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NMR solution structure of the focal adhesion targeting domain of focal adhesion kinase in complex with a paxillin LD peptide: evidence for a two-site binding model

31 March 2020

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Targeting membrane-localized focal adhesion kinase to focal adhesions: roles of tyrosine phosphorylation and SRC family kinases

31 March 2020

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The focal adhesion targeting domain of focal adhesion kinase contains a hinge region that modulates tyrosine 926 phosphorylation

31 March 2020

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Serine phosphorylation of focal adhesion kinase in interphase and mitosis: a possible role in modulating binding to p130(Cas).

31 March 2020

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PDGF and FGF induce focal adhesion kinase (FAK) phosphorylation at Ser-910: dissociation from Tyr-397 phosphorylation and requirement for ERK activation

31 March 2020

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Hepatocyte growth factor induces ERK-dependent paxillin phosphorylation and regulates paxillin-focal adhesion kinase association

31 March 2020

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Live-cell monitoring of tyrosine phosphorylation in focal adhesions following microtubule disruption.

31 March 2020

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Early molecular events in the assembly of matrix adhesions at the leading edge of migrating cells.

31 March 2020

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Dissecting the link between stress fibres and focal adhesions by CALI with EGFP fusion proteins.

31 March 2020

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The cytoskeletal/non-muscle isoform of alpha-actinin is phosphorylated on its actin-binding domain by the focal adhesion kinase

31 March 2020

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Protein-tyrosine phosphatase Shp-2 regulates cell spreading, migration, and focal adhesion

31 March 2020

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Force-dependent integrin-cytoskeleton linkage formation requires downregulation of focal complex dynamics by Shp2

31 March 2020

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v-Src rescues actin-based cytoskeletal architecture and cell motility and induces enhanced anchorage independence during oncogenic transformation of focal adhesion kinase-null fibroblasts

31 March 2020

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Reduced cell migration and disruption of the actin cytoskeleton in calpain-deficient embryonic fibroblasts

31 March 2020

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MEKK1 regulates calpain-dependent proteolysis of focal adhesion proteins for rear-end detachment of migrating fibroblasts.

31 March 2020

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SRC-mediated phosphorylation of focal adhesion kinase couples actin and adhesion dynamics to survival signaling

31 March 2020

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Calcium rises locally trigger focal adhesion disassembly and enhance residency of focal adhesion kinase at focal adhesions

31 March 2020

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Roles of Rho-associated kinase and myosin light chain kinase in morphological and migratory defects of focal adhesion kinase-null cells

31 March 2020

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Integrin engagement suppresses RhoA activity via a c-Src-dependent mechanism

31 March 2020

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Cortical control of microtubule stability and polarization

31 March 2020

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Integrins regulate Rac targeting by internalization of membrane domains

31 March 2020

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Adhesion to the extracellular matrix regulates the coupling of the small GTPase Rac to its effector PAK.

31 March 2020

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31 March 2020

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Phosphatidylinositol phosphate kinase type 1gamma and beta1-integrin cytoplasmic domain bind to the same region in the talin FERM domain

31 March 2020

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Tyrosine phosphorylation of type Igamma phosphatidylinositol phosphate kinase by Src regulates an integrin-talin switch

31 March 2020

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Cadherins as Modulators of Cellular Phenotype

31 March 2020

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Src-induced de-regulation of E-cadherin in colon cancer cells requires integrin signalling.

31 March 2020

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Endothelial barrier strengthening by activation of focal adhesion kinase.

31 March 2020

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Sensing the environment: a historical perspective on integrin signal transduction

31 March 2020

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The role of the dynamics of focal adhesion kinase in the mechanotaxis of endothelial cells

31 March 2020

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Focal adhesion kinase is involved in mechanosensing during fibroblast migration

31 March 2020

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Induced focal adhesion kinase (FAK) expression in FAK-null cells enhances cell spreading and migration requiring both auto- and activation loop phosphorylation sites and inhibits adhesion-dependent tyrosine phosphorylation of Pyk2.

31 March 2020

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Cell interactions with three-dimensional matrices

31 March 2020

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FAK promotes organization of fibronectin matrix and fibrillar adhesions.

31 March 2020

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ROCK-generated contractility regulates breast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrix

31 March 2020

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Plasma membrane-associated pY397FAK is a marker of cytotrophoblast invasion in vivo and in vitro

31 March 2020

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Invadopodia: unique methods for measurement of extracellular matrix degradation in vitro.

31 March 2020

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The v-Src SH3 domain facilitates a cell adhesion-independent association with focal adhesion kinase

31 March 2020

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The focal adhesion kinase amino-terminal domain localises to nuclei and intercellular junctions in HEK 293 and MDCK cells independently of tyrosine 397 and the carboxy-terminal domain

31 March 2020

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Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase

31 March 2020

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Talin forges the links between integrins and actin

31 March 2020

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PYK2 autophosphorylation, but not kinase activity, is necessary for adhesion-induced association with c-Src, osteoclast spreading, and bone resorption

31 March 2020

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Identification of a novel family of targets of PYK2 related to Drosophila retinal degeneration B (rdgB) protein

31 March 2020

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Interleukin (IL)-7 induces rapid activation of Pyk2, which is bound to Janus kinase 1 and IL-7Ralpha

31 March 2020

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Inhibition of the calcium-dependent tyrosine kinase (CADTK) blocks monocyte spreading and motility

31 March 2020

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The adaptor protein paxillin is essential for normal development in the mouse and is a critical transducer of fibronectin signaling

31 March 2020

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31 March 2020

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30 April 2017

Consolidated OpenCitations Corpus – April 2017

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1014928904

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PubMed publication ID

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30 April 2017

Consolidated OpenCitations Corpus – April 2017