The integrin-actin connection, an eternal love affair (Q24676735)

Structural determinants of integrin recognition by talin

Europe PubMed Central

title

The integrin-actin connection, an eternal love affair (English)

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author

Reinhard Fässler

series ordinal

2

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Cord Brakebusch

series ordinal

1

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language of work or name

English

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publication date

15 May 2003

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published in

The EMBO Journal

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volume

22

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page(s)

2324-33

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issue

10

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cites work

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Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites

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The integrin cytoplasmic domain-associated protein ICAP-1 binds and regulates Rho family GTPases during cell spreading

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A novel integrin-linked kinase-binding protein, affixin, is involved in the early stage of cell-substrate interaction

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Conformation, localization, and integrin binding of talin depend on its interaction with phosphoinositides

7 April 2017

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Parvin, a 42 kDa focal adhesion protein, related to the alpha-actinin superfamily

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7 April 2017

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7 April 2017

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Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling

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7 April 2017

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Filamin binds to the cytoplasmic domain of the beta1-integrin. Identification of amino acids responsible for this interaction

7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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Paxillin, a tyrosine phosphorylated focal adhesion-associated protein binds to the carboxyl terminal domain of focal adhesion kinase

7 April 2017

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7 April 2017

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7 April 2017

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Interaction of alphaPIX (ARHGEF6) with beta-parvin (PARVB) suggests an involvement of alphaPIX in integrin-mediated signaling

7 April 2017

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Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions

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Filamin is essential in actin cytoskeletal assembly mediated by p21-activated kinase 1

7 April 2017

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Characterization of PINCH-2, a new focal adhesion protein that regulates the PINCH-1-ILK interaction, cell spreading, and migration

7 April 2017

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Increased filamin binding to beta-integrin cytoplasmic domains inhibits cell migration

7 April 2017

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7 April 2017

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30 May 2018

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30 May 2018

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30 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156003

Phosphatidylinositol 3-kinase binds to alpha-actinin through the p85 subunit

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156003

Redundancy in the microfilament system: Abnormal development of dictyostelium cells lacking two F-actin cross-linking proteins

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156003

Identification of a plasma membrane Raft-associated PKB Ser473 kinase activity that is distinct from ILK and PDK1.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156003

C. elegans PAT-4/ILK functions as an adaptor protein within integrin adhesion complexes

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156003

A crucial role of beta 1 integrins for keratinocyte migration in vitro and during cutaneous wound repair

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156003

Mammary epithelial-specific expression of the integrin-linked kinase (ILK) results in the induction of mammary gland hyperplasias and tumors in transgenic mice.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156003

The cytoskeletal/non-muscle isoform of alpha-actinin is phosphorylated on its actin-binding domain by the focal adhesion kinase

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156003

Association of beta 1 integrin with focal adhesion kinase and paxillin in differentiating Schwann cells.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156003

Drosophila filamin encoded by the cheerio locus is a component of ovarian ring canals

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156003

Characterization of lethal Drosophila melanogaster alpha-actinin mutants.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156003

Mutations in filamin 1 prevent migration of cerebral cortical neurons in human periventricular heterotopia.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156003

Photosensory and thermosensory responses in Dictyostelium slugs are specifically impaired by absence of the F-actin cross-linking gelation factor (ABP-120).

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156003

Functions for PS integrins in tissue adhesion, migration, and shape changes during early embryonic development in Drosophila

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156003

Role of actin-binding protein in insertion of adhesion receptors into the membrane

28 November 2018

1 reference

12 December 2020

Requirement of phosphatidylinositol 3-kinase in focal adhesion kinase-promoted cell migration

1 reference

12 December 2020

Three actin cross-linking proteins, the 34 kDa actin-bundling protein, alpha-actinin and gelation factor (ABP-120), have both unique and redundant roles in the growth and development of Dictyostelium

1 reference

12 December 2020

Differential expression of laminin chains and anti-laminin autoantibodies in experimental lupus nephritis

1 reference

12 December 2020

Antifilamin, antivinculin, and antitropomyosin antibodies in myasthenia gravis

1 reference

12 December 2020

Specific interaction of vinculin with alpha-actinin

1 reference

12 December 2020

Purification and characterization of zyxin, an 82,000-dalton component of adherens junctions

1 reference

12 December 2020

Direct interaction of filamin (ABP-280) with the beta 2-integrin subunit CD18

1 reference

12 December 2020

Periventricular Heterotopia: An X-Linked Dominant Epilepsy Locus Causing Aberrant Cerebral Cortical Development

1 reference

12 December 2020

release_hfdfvewqdvffrgjj6zr33ef3zy

Identifiers

DOI

10.1093/EMBOJ/CDG245

0 references

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/hfdfvewqdvffrgjj6zr33ef3zy

24 November 2022