Prion protein-mediated toxicity of amyloid-β oligomers requires lipid rafts and the transmembrane LRP1 (Q28910209)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23386614%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

title

Prion protein-mediated toxicity of amyloid-β oligomers requires lipid rafts and the transmembrane LRP1 (English)

2 references

7 March 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23386614%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

main subject

prion protein family

0 references

transmembrane protein

0 references

Major prion protein

1 reference

LDL receptor related protein 1

1 reference

1 reference

FYN proto-oncogene, Src family tyrosine kinase

1 reference

positive regulation of protein localization to plasma membrane

1 reference

Prion protein

1 reference

1 reference

0 references

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23386614%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

author name string

Jo V Rushworth

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23386614%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Heledd H Griffiths

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23386614%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Nicole T Watt

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23386614%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

language of work or name

English

0 references

publication date

5 February 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23386614%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

23 February 2020

published in

2 references

7 March 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23386614%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

volume

288

2 references

7 March 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23386614%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

page(s)

8935-8951

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23386614%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

issue

13

2 references

7 March 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23386614%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

23 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3610967/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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Protective effect of prion protein via the N-terminal region in mediating a protective effect on paraquat-induced oxidative injury in neuronal cells

3 June 2018

1 reference

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Conformation-dependent anti-amyloid oligomer antibodies

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610967

The prion protein and lipid rafts

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610967

Proteolytic mechanisms in amyloid-beta metabolism: therapeutic implications for Alzheimer's disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610967

Cellular prion protein neuroprotective function: implications in prion diseases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610967

Overexpression of PrPc triggers caspase 3 activation: potentiation by proteasome inhibitors and blockade by anti-PrP antibodies

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610967

Signal transduction through prion protein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610967

Cellular prion protein localization in rodent and primate brain.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610967

Bicistronic vector for the creation of stable mammalian cell lines that predisposes all antibiotic-resistant cells to express recombinant protein.

3 June 2018

1 reference

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Ablation of the metal ion-induced endocytosis of the prion protein by disease-associated mutation of the octarepeat region

3 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.400358

Self-assembly of Abeta(1-42) into globular neurotoxins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.400358

Neurotoxicity and memory deficits induced by soluble low-molecular-weight amyloid-β1-42 oligomers are revealed in vivo by using a novel animal model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.400358

Fyn kinase induces synaptic and cognitive impairments in a transgenic mouse model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.400358

The low-density lipoprotein receptor-related protein 1 (LRP1) mediates the endocytosis of the cellular prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.400358

Differential expression of cellular prion protein in mouse brain as detected with multiple anti-PrP monoclonal antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.400358

Amyloid-beta oligomers increase the localization of prion protein at the cell surface

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.400358

The low-density lipoprotein receptor-related protein-1 associates transiently with lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.400358

Alzheimer's disease: A prion protein connection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.400358

Tethering the N-terminus of the prion protein compromises the cellular response to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.400358

Membrane-bound β-amyloid oligomers are recruited into lipid rafts by a fyn-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.400358

Fyn-tau-amyloid: a toxic triad

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23386614

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

LRP1 controls biosynthetic and endocytic trafficking of neuronal prion protein

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23386614

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M112.400358

2 references

7 March 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23386614%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23386614%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

2 references

7 March 2017