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FYN proto-oncogene, Src family tyrosine kinase (Q423628)

From Wikidata
mammalian protein found in Homo sapiens
  • src-like kinase
  • FYN oncogene related to SRC, FGR, YES
  • tyrosine-protein kinase Fyn
  • SLK
  • OKT3-induced calcium influx regulator
  • c-syn protooncogene
  • FYN
  • tyrosine kinase p59fyn(T)
  • p59-Fyn
  • proto-oncogene Syn
  • proto-oncogene c-Fyn
  • src/yes-related novel
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    English
    FYN proto-oncogene, Src family tyrosine kinase
    mammalian protein found in Homo sapiens
    • src-like kinase
    • FYN oncogene related to SRC, FGR, YES
    • tyrosine-protein kinase Fyn
    • SLK
    • OKT3-induced calcium influx regulator
    • c-syn protooncogene
    • FYN
    • tyrosine kinase p59fyn(T)
    • p59-Fyn
    • proto-oncogene Syn
    • proto-oncogene c-Fyn
    • src/yes-related novel

    Statements

    image
    PBB Protein FYN image.jpg
    500 × 500; 22 KB
    media legend
    Структура фрагмента Fyn-киназы (Russian)
    1 reference
    imported from Wikimedia project
    Russian Wikipedia
    Wikimedia import URL
    https://ru.wikipedia.org/?oldid=139753088
    molecular function
    protein binding
    determination method or standard
    IPI
    45 references
    retrieved
    8 April 2019
    stated in
    ARAP, a Novel Adaptor Protein, Is Required for TCR Signaling and Integrin-Mediated Adhesion
    GOA
    curator
    UniProt
    UniProt protein ID
    P06241
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The adaptor protein Tom1L1 is a negative regulator of Src mitogenic signaling induced by growth factors
    GOA
    curator
    UniProt
    UniProt protein ID
    P06241
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Unc119, a novel activator of Lck/Fyn, is essential for T cell activation
    GOA
    curator
    UniProt
    UniProt protein ID
    P06241
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Regulation of protein arginine methyltransferase 8 (PRMT8) activity by its N-terminal domain
    GOA
    curator
    UniProt
    UniProt protein ID
    P06241
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Src kinase phosphorylates RUNX3 at tyrosine residues and localizes the protein in the cytoplasm
    GOA
    curator
    UniProt
    UniProt protein ID
    P06241
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Molecular cloning of SKAP55, a novel protein that associates with the protein tyrosine kinase p59fyn in human T-lymphocytes
    GOA
    curator
    UniProt
    UniProt protein ID
    P06241
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    SHP2-interacting transmembrane adaptor protein (SIT), a novel disulfide-linked dimer regulating human T cell activation
    GOA
    curator
    UniProt
    UniProt protein ID
    P06241
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation
    GOA
    curator
    UniProt
    UniProt protein ID
    P06241
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Tau interacts with src-family non-receptor tyrosine kinases
    GOA
    curator
    UniProt
    UniProt protein ID
    P06241
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    UNC119a bridges the transmission of Fyn signals to Rab11, leading to the completion of cytokinesis
    GOA
    curator
    UniProt
    UniProt protein ID
    P06241
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Further studies on hepatitis C virus NS5A-SH3 domain interactions: identification of residues critical for binding and implications for viral RNA replication and modulation of cell signalling
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Metabotropic glutamate receptor 5 is a coreceptor for Alzheimer aβ oligomer bound to cellular prion protein
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Membrane glycoprotein IV (CD36) is physically associated with the Fyn, Lyn, and Yes protein-tyrosine kinases in human platelets
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Targeting AMAP1 and cortactin binding bearing an atypical src homology 3/proline interface for prevention of breast cancer invasion and metastasis
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Physical and functional interaction of Fyn tyrosine kinase with a brain-enriched Rho GTPase-activating protein TCGAP
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Interaction between Sam68 and Src family tyrosine kinases, Fyn and Lck, in T cell receptor signaling
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Molecular priming of Lyn by GPVI enables an immune receptor to adopt a hemostatic role
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Csk inhibition of c-Src activity requires both the SH2 and SH3 domains of Src
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The hepatitis C virus NS5A protein binds to members of the Src family of tyrosine kinases and regulates kinase activity
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Regulation of FynT function by dual domain docking on PAG/Cbp
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    FYN-T-FYB-SLP-76 interactions define a T-cell receptor zeta/CD3-mediated tyrosine phosphorylation pathway that up-regulates interleukin 2 transcription in T-cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Tyrosine phosphorylation of Crk-associated substrates by focal adhesion kinase. A putative mechanism for the integrin-mediated tyrosine phosphorylation of Crk-associated substrates
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    EG-1 interacts with c-Src and activates its signaling pathway
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Identification of a Src kinase SH3 binding site in the C-terminal domain of the human ErbB2 receptor tyrosine kinase
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Physical and functional interaction between protein kinase C delta and Fyn tyrosine kinase in human platelets
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    p250GAP, a neural RhoGAP protein, is associated with and phosphorylated by Fyn
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Identification of preferred protein interactions by phage-display of the human Src homology-3 proteome
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Structural recognition mechanisms between human Src homology domain 3 (SH3) and ALG-2-interacting protein X (Alix)
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Platelet-derived growth factor receptor sequences important for binding of src family tyrosine kinases
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Phosphorylation-dependent interactions between ADAM15 cytoplasmic domain and Src family protein-tyrosine kinases
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Magicin associates with the Src-family kinases and is phosphorylated upon CD3 stimulation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Phospho-tyrosine dependent protein-protein interaction network
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Direct interaction in T-cells between thetaPKC and the tyrosine kinase p59fyn
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Influence of CRACC, a SLAM family receptor coupled to the adaptor EAT-2, on natural killer cell function
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Identification of two juxtamembrane autophosphorylation sites in the PDGF beta-receptor; involvement in the interaction with Src family tyrosine kinases
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Lyn, a Src family kinase, regulates activation of epidermal growth factor receptors in lung adenocarcinoma cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A novel, non-immunogenic Fyn SH3-derived binding protein with tumor vascular targeting properties
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A proteome-scale map of the human interactome network
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    ABL2 suppresses FLT3-ITD-induced cell proliferation through negative regulation of AKT signaling.
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The novel cellular mechanism of human 5-HT6 receptor through an interaction with Fyn
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Mast cell costimulation by CD226/CD112 (DNAM-1/Nectin-2): a novel interface in the allergic process
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IPI
    protein tyrosine kinase activity
    determination method or standard
    IEA
    EXP
    TAS
    IMP
    15 references
    retrieved
    14 February 2017
    stated in
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P06241
    determination method or standard
    TAS
    retrieved
    14 February 2017
    stated in
    Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice
    GOA
    curator
    Proteome Inc.
    reference URL
    http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P06241
    determination method or standard
    TAS
    retrieved
    14 February 2017
    stated in
    Phosphorylation at Tyr-694 of Nogo-A by Src-family kinases
    GOA
    curator
    UniProt
    UniProt protein ID
    P06241
    reference URL
    http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P06241
    determination method or standard
    IMP
    retrieved
    14 February 2017
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    P06241
    reference URL
    http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P06241
    determination method or standard
    IEA
    retrieved
    14 February 2017
    stated in
    GOA
    curator
    InterPro
    reference URL
    http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P06241
    determination method or standard
    IEA
    retrieved
    14 February 2017
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P06241
    determination method or standard
    IEA
    retrieved
    14 February 2017
    stated in
    C-type lectin DC-SIGN modulates Toll-like receptor signaling via Raf-1 kinase-dependent acetylation of transcription factor NF-kappaB
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P06241
    determination method or standard
    EXP
    retrieved
    14 February 2017
    stated in
    Steel factor stimulates the tyrosine phosphorylation of the proto-oncogene product, p95vav, in human hemopoietic cells
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P06241
    determination method or standard
    EXP
    retrieved
    14 February 2017
    stated in
    Kit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferation
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P06241
    determination method or standard
    EXP
    retrieved
    14 February 2017
    stated in
    Fyn and Lyn phosphorylate the Fc receptor gamma chain downstream of glycoprotein VI in murine platelets, and Lyn regulates a novel feedback pathway
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P06241
    determination method or standard
    EXP
    retrieved
    14 February 2017
    stated in
    Differential kinase requirements in human and mouse Fc-gamma receptor phagocytosis and endocytosis
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P06241
    determination method or standard
    EXP
    retrieved
    14 February 2017
    stated in
    Vav2 is required for cell spreading
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P06241
    determination method or standard
    EXP
    retrieved
    14 February 2017
    stated in
    Tyrosyl phosphorylation of Shp2 is required for normal ERK activation in response to some, but not all, growth factors
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P06241
    determination method or standard
    EXP
    retrieved
    14 February 2017
    stated in
    Differential involvement of Src family kinases in Fc gamma receptor-mediated phagocytosis
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P06241
    determination method or standard
    EXP
    retrieved
    14 February 2017
    stated in
    Gab2 is involved in differential phosphoinositide 3-kinase signaling by two splice forms of c-Kit
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P06241
    determination method or standard
    EXP
    protein tyrosine kinase activity
    determination method or standard
    EXP
    IEA
    IMP
    ISS
    TAS
    15 references
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    TAS
    retrieved
    8 April 2019
    stated in
    Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice
    GOA
    curator
    Proteome Inc.
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    TAS
    retrieved
    8 April 2019
    stated in
    Roles of tau protein in health and disease
    GOA
    curator
    ARUK-UCL
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    TAS
    retrieved
    8 April 2019
    stated in
    Fyn-mediated phosphorylation of NR2B Tyr-1336 controls calpain-mediated NR2B cleavage in neurons and heterologous systems
    GOA
    curator
    ARUK-UCL
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    TAS
    retrieved
    8 April 2019
    stated in
    Fyn-mediated phosphorylation of NR2B Tyr-1336 controls calpain-mediated NR2B cleavage in neurons and heterologous systems
    GOA
    curator
    ARUK-UCL
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    ISS
    retrieved
    8 April 2019
    stated in
    Phosphorylation at Tyr-694 of Nogo-A by Src-family kinases
    GOA
    curator
    UniProt
    UniProt protein ID
    P06241
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    P06241
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    InterPro
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    Tyrosyl phosphorylation of Shp2 is required for normal ERK activation in response to some, but not all, growth factors
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    EXP
    retrieved
    8 April 2019
    stated in
    Vav2 is required for cell spreading
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    EXP
    retrieved
    8 April 2019
    stated in
    Dynamically Coupled Residues within the SH2 Domain of FYN Are Key to Unlocking Its Activity
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    EXP
    retrieved
    8 April 2019
    stated in
    Gab2 is involved in differential phosphoinositide 3-kinase signaling by two splice forms of c-Kit
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    EXP
    retrieved
    8 April 2019
    stated in
    Kit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferation
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    EXP
    retrieved
    8 April 2019
    stated in
    Steel factor stimulates the tyrosine phosphorylation of the proto-oncogene product, p95vav, in human hemopoietic cells
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06241
    determination method or standard
    EXP
    cell component
    biological process
    Gene Atlas image
    PBB GE FYN 210105 s at fs.png
    732 × 530; 11 KB
    0 references

    Identifiers

    MeSH descriptor ID
    D051076
    subject named as
    Proto-Oncogene Proteins c-fyn
    0 references
    Ensembl protein ID
    Freebase ID
    /m/03cc30q
    0 references
    PDB structure ID
     
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                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q423628&oldid=2412952582"