The anaphase-promoting complex: proteolysis in mitosis and beyond (Q28610045)

3 February 2017

title

The anaphase-promoting complex: proteolysis in mitosis and beyond (English)

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3 February 2017

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1

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publication date

1 May 2002

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3 February 2017

language of work or name

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3 February 2017

volume

9

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3 February 2017

issue

5

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3 February 2017

page(s)

931–943

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publication type of scholarly work

3 February 2017

review article

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Distinct Initiation and Maintenance Mechanisms Cooperate to Induce G1 Cell Cycle Arrest in Response to DNA Damage

Europe PubMed Central

cites work

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https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

The spindle checkpoint

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7 January 2021

Closing the cell cycle circle in yeast: G2 cyclin proteolysis initiated at mitosis persists until the activation of G1 cyclins in the next cycle.

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7 January 2021

Implications for the ubiquitination reaction of the anaphase-promoting complex from the crystal structure of the Doc1/Apc10 subunit

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7 January 2021

MEN and SIN: what's the difference?

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7 January 2021

A Mechanism for Coupling Exit from Mitosis to Partitioning of the Nucleus

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7 January 2021

Two different modes of cyclin clb2 proteolysis during mitosis in Saccharomyces cerevisiae

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https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Regulation of the anaphase-promoting complex by the dual specificity phosphatase human Cdc14a

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

APC(ste9/srw1) promotes degradation of mitotic cyclins in G(1) and is inhibited by cdc2 phosphorylation.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

D box and KEN box motifs in budding yeast Hsl1p are required for APC-mediated degradation and direct binding to Cdc20p and Cdh1p

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Association of spindle assembly checkpoint component XMAD2 with unattached kinetochores

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Temporal and spatial control of cyclin B1 destruction in metaphase

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

The Drosophila cell cycle gene fizzy is required for normal degradation of cyclins A and B during mitosis and has homology to the CDC20 gene of Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Cyclin A is destroyed in prometaphase and can delay chromosome alignment and anaphase

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

SCF and Cullin/Ring H2-based ubiquitin ligases

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Control of G1 in the developing Drosophila eye: rca1 regulates Cyclin A.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Cyclin: a protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Direct Binding of CDC20 Protein Family Members Activates the Anaphase-Promoting Complex in Mitosis and G1

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

The Xenopus chromokinesin Xkid is essential for metaphase chromosome alignment and must be degraded to allow anaphase chromosome movement

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Expression of the CDH1-associated form of the anaphase-promoting complex in postmitotic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Three-dimensional structure of the anaphase-promoting complex

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Cyclin is degraded by the ubiquitin pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Degradation of the kinesin Kip1p at anaphase onset is mediated by the anaphase-promoting complex and Cdc20p

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Characterization of the DOC1/APC10 subunit of the yeast and the human anaphase-promoting complex

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Rca1 Inhibits APC-Cdh1Fzr and Is Required to Prevent Cyclin Degradation in G2

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

APC/C-mediated destruction of the centrosomal kinase Nek2A occurs in early mitosis and depends upon a cyclin A-type D-box

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Cohesin cleavage by separase required for anaphase and cytokinesis in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Cell Cycle-dependent Degradation of theSaccharomyces cerevisiaeSpindle Motor Cin8p Requires APCCdh1and a Bipartite Destruction Sequence

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

The anaphase inhibitor Pds1 binds to the APC/C-associated protein Cdc20 in a destruction box-dependent manner

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Anaphase is initiated by proteolysis rather than by the inactivation of maturation-promoting factor.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Activity of the APC(Cdh1) form of the anaphase-promoting complex persists until S phase and prevents the premature expression of Cdc20p

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

A Novel Yeast Screen for Mitotic Arrest Mutants IdentifiesDOC1, a New Gene Involved in Cyclin Proteolysis

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Budding yeast Cdc20: a target of the spindle checkpoint.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Securin is required for chromosomal stability in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Inhibitory phosphorylation of the APC regulator Hct1 is controlled by the kinase Cdc28 and the phosphatase Cdc14.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

APC-mediated proteolysis of Ase1 and the morphogenesis of the mitotic spindle

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Fission Yeast Ste9, a Homolog of Hct1/Cdh1 and Fizzy-related, Is a Novel Negative Regulator of Cell Cycle Progression during G1-Phase

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Apc10 and Ste9/Srw1, two regulators of the APC–cyclosome, as well as the CDK inhibitor Rum1 are required for G1 cell-cycle arrest in fission yeast

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Mitotic regulation of the APC activator proteins CDC20 and CDH1

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

The APC11 RING-H2 finger mediates E2-dependent ubiquitination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Mitotic forces control a cell-cycle checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Cdk1 is essential for mammalian cyclosome/APC regulation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Fizzy is required for activation of the APC/cyclosome in Xenopus egg extracts

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Identification of Xenopus SMC protein complexes required for sister chromatid cohesion

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

TGFbeta signaling in growth control, cancer, and heritable disorders

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Regulation of the APC and the exit from mitosis

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Disseminating the Genome: Joining, Resolving, and Separating Sister Chromatids During Mitosis and Meiosis

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

CDK Inactivation Is the Only Essential Function of the APC/C and the Mitotic Exit Network Proteins for Origin Resetting during Mitosis

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Human p55(CDC)/Cdc20 associates with cyclin A and is phosphorylated by the cyclin A-Cdk2 complex

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Subunits and substrates of the anaphase-promoting complex

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Identification of BIME as a subunit of the anaphase-promoting complex

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Substrate recognition by the Cdc20 and Cdh1 components of the anaphase-promoting complex

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Inhibition of Cdh1-APC by the MAD2-related protein MAD2L2: a novel mechanism for regulating Cdh1

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

The regulation of Cdc20 proteolysis reveals a role for APC components Cdc23 and Cdc27 during S phase and early mitosis

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Emi1 regulates the anaphase-promoting complex by a different mechanism than Mad2 proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Anaphase onset in vertebrate somatic cells is controlled by a checkpoint that monitors sister kinetochore attachment to the spindle

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Phosphorylation by Cdc28 activates the Cdc20-dependent activity of the anaphase-promoting complex

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Yeast Hct1 Is a Regulator of Clb2 Cyclin Proteolysis

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Yeast Hct1 recognizes the mitotic cyclin Clb2 and other substrates of the ubiquitin ligase APC.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

The Polo-like kinase Cdc5p and the WD-repeat protein Cdc20p/fizzy are regulators and substrates of the anaphase promoting complex in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Phosphorylation of the cyclosome is required for its stimulation by Fizzy/cdc20.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Drosophila fizzy-related Down-Regulates Mitotic Cyclins and Is Required for Cell Proliferation Arrest and Entry into Endocycles

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Mad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for the spindle checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Mammalian mad2 and bub1/bubR1 recognize distinct spindle-attachment and kinetochore-tension checkpoints

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

A conserved cyclin-binding domain determines functional interplay between anaphase-promoting complex-Cdh1 and cyclin A-Cdk2 during cell cycle progression

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Separase, polo kinase, the kinetochore protein Slk19, and Spo12 function in a network that controls Cdc14 localization during early anaphase

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Dual inhibition of sister chromatid separation at metaphase

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Lack of tension at kinetochores activates the spindle checkpoint in budding yeast

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Cell cycle: how, when and why cells get rid of cyclin A.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Activation of Cdh1-dependent APC is required for G1 cell cycle arrest and DNA damage-induced G2 checkpoint in vertebrate cells

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

The dissociation of cohesin from chromosomes in prophase is regulated by Polo-like kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Mad2-Independent Inhibition of APCCdc20 by the Mitotic Checkpoint Protein BubR1

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

APC2 Cullin Protein and APC11 RING Protein Comprise the Minimal Ubiquitin Ligase Module of the Anaphase-promoting Complex

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

CDC27Hs colocalizes with CDC16Hs to the centrosome and mitotic spindle and is essential for the metaphase to anaphase transition

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

The phosphatase Cdc14 triggers mitotic exit by reversal of Cdk-dependent phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Two distinct pathways remove mammalian cohesin from chromosome arms in prophase and from centromeres in anaphase

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Identification of multiple CDH1 homologues in vertebrates conferring different substrate specificities

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

The Anaphase-Promoting Complex Mediates TGF-β Signaling by Targeting SnoN for Destruction

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Mad2 transiently associates with an APC/p55Cdc complex during mitosis

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Localization of Mad2 to Kinetochores Depends on Microtubule Attachment, Not Tension

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Crystal structure of the APC10/DOC1 subunit of the human anaphase-promoting complex

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Fission yeast Fizzy-related protein srw1p is a G(1)-specific promoter of mitotic cyclin B degradation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Pds1p, an inhibitor of anaphase in budding yeast, plays a critical role in the APC and checkpoint pathway(s).

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Cell cycle-dependent expression of mammalian E2-C regulated by the anaphase-promoting complex/cyclosome

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Exit from Mitosis in Budding Yeast

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Identification of a novel ubiquitin-conjugating enzyme involved in mitotic cyclin degradation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Identification of a Cullin Homology Region in a Subunit of the Anaphase-Promoting Complex

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Whose end is destruction: cell division and the anaphase-promoting complex

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Mass spectrometric analysis of the anaphase-promoting complex from yeast: identification of a subunit related to cullins.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900540-3

7 January 2021