Mutations in GDF5 reveal a key residue mediating BMP inhibition by NOGGIN (Q28587807)

Growth differentiation factor 2

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

5

Sigmar Stricker

0 references

Andreas Janecke

18

Mareen Schmidt-von Kegler

Andreas R. Janecke

1 reference

31 January 2017

20

Stefan Mundlos

1 reference

31 January 2017

14

Mareen Schmidt-von Kegler

0 references

Katarina Dathe

Katarina Dathe

19

0 references

Petra Seemann

Petra Seemann

1

0 references

Carsten Reissner

Carsten Reissner

4

0 references

author name string

Anja Brehm

2

1 reference

31 January 2017

Jana König

3

1 reference

31 January 2017

Pia Kuss

6

1 reference

31 January 2017

Julia Haupt

7

1 reference

31 January 2017

Stephanie Renninger

8

1 reference

31 January 2017

Joachim Nickel

9

1 reference

31 January 2017

Walter Sebald

10

1 reference

31 January 2017

Jay C. Groppe

11

1 reference

31 January 2017

Frank Plöger

12

1 reference

31 January 2017

Jens Pohl

13

1 reference

31 January 2017

Mareen Schmidt-von Kegler

14

1 reference

31 January 2017

Maria Walther

15

1 reference

31 January 2017

Ingmar Gassner

16

1 reference

31 January 2017

Cristina Rusu

Creative Commons Attribution 4.0 International

17

1 reference

31 January 2017

1 November 2009

1 reference

31 January 2017

1 reference

31 January 2017

5

1 reference

31 January 2017

e1000747

1 reference

31 January 2017

11

1 reference

31 January 2017

start time

26 November 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

C2C12-Bmpr1b

0 references

cites work

Crystal structure analysis reveals a spring-loaded latch as molecular mechanism for GDF-5-type I receptor specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776984

Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776984

Activating and deactivating mutations in the receptor interaction site of GDF5 cause symphalangism or brachydactyly type A2

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776984

UCSF Chimera--a visualization system for exploratory research and analysis

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776984

Molecular recognition of BMP-2 and BMP receptor IA

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776984

Signal transduction of bone morphogenetic protein receptors

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776984

Structural basis of BMP signalling inhibition by the cystine knot protein Noggin

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776984

TGFbeta signaling in growth control, cancer, and heritable disorders

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776984

Controlling TGF-beta signaling

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776984

Heterozygous mutations in the gene encoding noggin affect human joint morphogenesis

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776984

Crystal structure of human bone morphogenetic protein-2 at 2.7 A resolution

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776984

Noggin, cartilage morphogenesis, and joint formation in the mammalian skeleton

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776984

Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776984

The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776984

Disruption of human limb morphogenesis by a dominant negative mutation in CDMP1

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776984

Mutations in CDMP1 cause autosomal dominant brachydactyly type C

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776984

The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776984

Bone: formation by autoinduction

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776984

A new subtype of brachydactyly type B caused by point mutations in the bone morphogenetic protein antagonist NOGGIN.

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776984

Gene identification and analysis of transcripts differentially regulated in fracture healing by EST sequencing in the domestic sheep

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776984

GDF5 is a second locus for multiple-synostosis syndrome.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776984

BMP signaling and early embryonic patterning.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776984

Crystal structure of recombinant human growth and differentiation factor 5: evidence for interaction of the type I and type II receptor-binding sites

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776984

Role of Runx genes in chondrocyte differentiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776984

Expression and function of Gdf-5 during digit skeletogenesis in the embryonic chick leg bud.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776984

Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776984

Bone morphogenetic proteins induce the expression of noggin, which limits their activity in cultured rat osteoblasts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776984

Manipulating gene expression with replication-competent retroviruses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776984

Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-beta, activin, and bone morphogenetic protein-inducible enhancer.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776984

Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776984

Brachydactyly type A2 associated with a defect in proGDF5 processing.

3 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000747

Coordinated expression of noggin and bone morphogenetic proteins (BMPs) during early skeletogenesis and induction of noggin expression by BMP-7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000747

Brachydactyly type C caused by a homozygous missense mutation in the prodomain of CDMP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000747

CHROMA: consensus-based colouring of multiple alignments for publication

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000747

A novel R486Q mutation in BMPR1B resulting in either a brachydactyly type C/symphalangism-like phenotype or brachydactyly type A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000747

Generation of transgenic tendon reporters, ScxGFP and ScxAP, using regulatory elements of the scleraxis gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000747

Interaction of Ihh and BMP/Noggin signaling during cartilage differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000747

The mutational spectrum of brachydactyly type C

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000747

A novel mutation in GDF5 causes autosomal dominant symphalangism in two Chinese families

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19956691

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Novel point mutations in GDF5 associated with two distinct limb malformations in Chinese: brachydactyly type C and proximal symphalangism

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19956691

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Myostatin in tendon maintenance and repair

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19956691

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PGEN.1000747

1 reference

463874

463874

1 reference

1 reference

1 reference