The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins (Q24324729)

positive regulation of GTPase activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Francis Collins

7

0 references

Douglas A Marchuk

1 reference

ORCID Public Data File 2021

author name string

R Ballester

1

0 references

D Marchuk

2

0 references

M Boguski

3

0 references

A Saulino

4

0 references

R Letcher

5

0 references

M Wigler

Autoradiography using storage phosphor technology

6

0 references

publication date

16 November 1990

0 references

language of work or name

0 references

0 references

63

0 references

issue

4

0 references

page(s)

851-9

0 references

cites work

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

A C-terminal domain of GAP is sufficient to stimulate ras p21 GTPase activity.

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

Genetic analysis of the role of cAMP in yeast

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

Weights for data related by a tree

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

[12] One-step gene disruption in yeast

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

Production of single-stranded plasmid DNA

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

Microinjection of the ras oncogene protein into PC12 cells induces morphological differentiation

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

In yeast, RAS proteins are controlling elements of adenylate cyclase.

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

The S. cerevisiae CDC25 gene product regulates the RAS/adenylate cyclase pathway

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

Genetic linkage of von Recklinghausen neurofibromatosis to the nerve growth factor receptor gene

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

Genetic analysis of mammalian GAP expressed in yeast

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

The neurofibromatosis type 1 gene encodes a protein related to GAP

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

S. cerevisiae genes IRA1 and IRA2 encode proteins that may be functionally equivalent to mammalian ras GTPase activating protein.

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

ras p21 and GAP inhibit coupling of muscarinic receptors to atrial K+ channels

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

Deletions and a translocation interrupt a cloned gene at the neurofibromatosis type 1 locus.

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

A major segment of the neurofibromatosis type 1 gene: cDNA sequence, genomic structure, and point mutations

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

Basic local alignment search tool

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

Sarcoma viruses carrying ras oncogenes induce differentiation-associated properties in a neuronal cell line

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

Inhibition of growth factor-induced differentiation of PC12 cells by microinjection of antibody to ras p21

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

The cytoplasmic protein GAP is implicated as the target for regulation by the ras gene product.

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

Cloning of bovine GAP and its interaction with oncogenic ras p21.

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

Suppression of c-ras transformation by GTPase-activating protein

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

Sequence homology shared by neurofibromatosis type-1 gene and IRA-1 and IRA-2 negative regulators of the RAS cyclic AMP pathway.

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

Predictive motifs derived from cytosine methyltransferases

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

Type 1 neurofibromatosis gene: identification of a large transcript disrupted in three NF1 patients

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

Physical mapping of a translocation breakpoint in neurofibromatosis

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

Two NF1 translocations map within a 600-kilobase segment of 17q11.2.

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

Guanosine triphosphatase activating protein (GAP) interacts with the p21 ras effector binding domain

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

Gene for von Recklinghausen neurofibromatosis is in the pericentromeric region of chromosome 17

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

Molecular cloning of two types of GAP complementary DNA from human placenta

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

CDC25: a component of the RAS-adenylate cyclase pathway in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

Effect of a dominant inhibitory Ha-ras mutation on neuronal differentiation of PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

IRA2, a second gene of Saccharomyces cerevisiae that encodes a protein with a domain homologous to mammalian ras GTPase-activating protein.

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

Purification and characterization of human H-ras proteins expressed in Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

Regulatory function of the Saccharomyces cerevisiae RAS C-terminus

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

Dominant yeast and mammalian RAS mutants that interfere with the CDC25-dependent activation of wild-type RAS in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

IRA1, an inhibitory regulator of the RAS-cyclic AMP pathway in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

7 January 2021

https://api.crossref.org/works/10.1016%2F0092-8674%2890%2990151-4

1 reference

7 January 2021