SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis (Q28583941)

8

0 references

Li-Huei Tsai

13

object named as

Li-Huei Tsai

1 reference

31 January 2017

Dohoon Kim

1

1 reference

31 January 2017

Minh Dang Nguyen

2

1 reference

31 January 2017

Matthew M. Dobbin

3

1 reference

31 January 2017

Andre Fischer

4

1 reference

31 January 2017

Farahnaz Sananbenesi

5

1 reference

31 January 2017

Joseph T. Rodgers

6

1 reference

31 January 2017

Guangchao Sui

9

1 reference

31 January 2017

Sean M. Armour

10

1 reference

31 January 2017

Pere Puigserver

11

1 reference

31 January 2017

David A. Sinclair

Sir2 blocks extreme life-span extension.

12

1 reference

31 January 2017

language of work or name

English

0 references

publication date

11 July 2007

1 reference

31 January 2017

1 reference

31 January 2017

26

1 reference

31 January 2017

3169–3179

1 reference

31 January 2017

13

1 reference

31 January 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

A local mechanism mediates NAD-dependent protection of axon degeneration

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Small molecules that regulate lifespan: evidence for xenohormesis

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

A NUDEL-dependent mechanism of neurofilament assembly regulates the integrity of CNS neurons

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Mammalian SIRT1 represses forkhead transcription factors

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Cdk5 phosphorylates p53 and regulates its activity

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Negative control of p53 by Sir2alpha promotes cell survival under stress

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Neurotoxicity induces cleavage of p35 to p25 by calpain

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

A DNA vector-based RNAi technology to suppress gene expression in mammalian cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Unraveling the mechanisms involved in motor neuron degeneration in ALS

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

SIRT1, neuronal cell survival and the insulin/IGF-1 aging paradox

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Alzheimer's disease: channeling APP to non-amyloidogenic processing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Calorie restriction, SIRT1 and metabolism: understanding longevity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

DNA repair, genome stability, and aging

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Cell biology of protein misfolding: the examples of Alzheimer's and Parkinson's diseases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Neurodegenerative diseases: a decade of discoveries paves the way for therapeutic breakthroughs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Molecular pathways to neurodegeneration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

A Jekyll and Hyde kinase: roles for Cdk5 in brain development and disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Yeast life-span extension by calorie restriction is independent of NAD fluctuation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Cycling at the interface between neurodevelopment and neurodegeneration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

p25/cyclin-dependent kinase 5 induces production and intraneuronal accumulation of amyloid beta in vivo.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Opposing roles of transient and prolonged expression of p25 in synaptic plasticity and hippocampus-dependent memory.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Distinct roles of hippocampal de novo protein synthesis and actin rearrangement in extinction of contextual fear.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Mitotic-like tau phosphorylation by p25-Cdk5 kinase complex

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Processing of cdk5 Activator p35 to Its Truncated Form (p25) by Calpain in Acutely Injured Neuronal Cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914106

Calpain-dependent proteolytic cleavage of the p35 cyclin-dependent kinase 5 activator to p25

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17581637

12 December 2020

inferred from PubMed ID database lookup

Emerging pathogenic role for cyclin dependent kinases in neurodegeneration

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17581637

12 December 2020

inferred from PubMed ID database lookup

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17581637

12 December 2020

inferred from PubMed ID database lookup

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7601758

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/SJ.EMBOJ.7601758

1 reference

747118

747118

1 reference

1 reference

1 reference