Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions (Q28591963)

Neurofilament, light polypeptide

inferred from title

1 reference

Cyclin-dependent kinase 5

GOA release 2020-03-11

1 reference

Superoxide dismutase 1, soluble

GOA release 2020-03-11

1 reference

Hyperphosphorylated tau and neurofilament and cytoskeletal disruptions in mice overexpressing human p25, an activator of cdk5

GOA release 2020-03-11

toxicity

0 references

author name string

M. D. Nguyen

series ordinal

1

1 reference

31 January 2017

R. C. Larivière

series ordinal

2

1 reference

31 January 2017

J. P. Julien

series ordinal

3

1 reference

31 January 2017

language of work or name

English

0 references

publication date

1 April 2001

1 reference

31 January 2017

1 reference

31 January 2017

30

1 reference

31 January 2017

135–147

1 reference

31 January 2017

1

1 reference

31 January 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Phosphorylation of neurofilament heavy-chain side-arm fragments by cyclin-dependent kinase-5 and glycogen synthase kinase-3alpha in transfected cells

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Cyclin-dependent kinase-5 is associated with lipofuscin in motor neurones in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Cyclin dependent kinase-5 (CDK-5) phosphorylates neurofilament heavy (NF-H) chain to generate epitopes for antibodies that label neurofilament accumulations in amyotrophic lateral sclerosis (ALS) and is present in affected motor neurones in ALS

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases cdk2 and cdk5

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Late onset of motor neurons in mice overexpressing wild-type peripherin

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Formation of intermediate filament protein aggregates with disparate effects in two transgenic mouse models lacking the neurofilament light subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

ALS, SOD and peroxynitrite

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Proximal axonal enlargement in motor neuron disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

From Charcot to SOD1: mechanisms of selective motor neuron death in ALS.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Chaperone-facilitated copper binding is a property common to several classes of familial amyotrophic lateral sclerosis-linked superoxide dismutase mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: a mouse model of amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Protective effect of neurofilament heavy gene overexpression in motor neuron disease induced by mutant superoxide dismutase

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Epidemiology of mutations in superoxide dismutase in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu,Zn SOD, and in mice overexpressing wild type human SOD: a model of familial amyotrophic lateral sclerosis (FALS).

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Pathogenesis of two axonopathies does not require axonal neurofilaments.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Mutant superoxide dismutase-1-linked familial amyotrophic lateral sclerosis: molecular mechanisms of neuronal death and protection

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Aberrant stress-induced phosphorylation of perikaryal neurofilaments

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Alterations in cyclin-dependent protein kinase 5 (CDK5) protein levels, activity and immunocytochemistry in canine motor neuron disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Differential cellular phosphorylation of neurofilament heavy side-arms by glycogen synthase kinase-3 and cyclin-dependent kinase-5.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Fine structural study of neurofibrillary changes in a family with amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Parvalbumin and calbindin D-28k in the human motor system and in motor neuron disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Age-Dependent Emergence and Progression of a Tauopathy in Transgenic Mice Overexpressing the Shortest Human Tau Isoform

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Neurofilament functions in health and disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Amyotrophic lateral sclerosis. unfolding the toxicity of the misfolded

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Calpain-dependent proteolytic cleavage of the p35 cyclin-dependent kinase 5 activator to p25

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

A novel disruption of cortical development in p35(-/-) mice distinct from reeler.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Neuronal intermediate filaments

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Neurotoxicity induces cleavage of p35 to p25 by calpain

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Structure, function, and regulation of neuronal Cdc2-like protein kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Functional Role of Caspase-1 and Caspase-3 in an ALS Transgenic Mouse Model

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Alzheimer's disease. The tangled tale of tau.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Quantitative immunocytochemical analysis of the spinal cord in G86R superoxide dismutase transgenic mice: neurochemical correlates of selective vulnerability

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Caspase-1 is activated in neural cells and tissue with amyotrophic lateral sclerosis-associated mutations in copper-zinc superoxide dismutase.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Accumulation of cyclin-dependent kinase 5 (cdk5) in neurons with early stages of Alzheimer's disease neurofibrillary degeneration.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

SOD1 mutation is associated with accumulation of neurofilaments in amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Glutamate potentiates the toxicity of mutant Cu/Zn-superoxide dismutase in motor neurons by postsynaptic calcium-dependent mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

SOD1 mutants linked to amyotrophic lateral sclerosis selectively inactivate a glial glutamate transporter.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Mitogen-activated protein kinases (Erk1,2) phosphorylate Lys-Ser-Pro (KSP) repeats in neurofilament proteins NF-H and NF-M.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Cdk5 and MAPK are associated with complexes of cytoskeletal proteins in rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Absence of neurofilaments reduces the selective vulnerability of motor neurons and slows disease caused by a familial amyotrophic lateral sclerosis-linked superoxide dismutase 1 mutant

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Preferential labeling of Alzheimer neurofibrillary tangles with antisera for tau protein kinase (TPK) I/glycogen synthase kinase-3 beta and cyclin-dependent kinase 5, a component of TPK II.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Neurofilaments and orthograde transport are reduced in ventral root axons of transgenic mice that express human SOD1 with a G93A mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Delayed maturation of regenerating myelinated axons in mice lacking neurofilaments

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

Disruption of the NF-H gene increases axonal microtubule content and velocity of neurofilament transport: relief of axonopathy resulting from the toxin beta,beta'-iminodipropionitrile

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900268-9

7 January 2021

10.1016/S0896-6273(01)00268-9

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

release_cfhzobufhffvbeeqnbm4vo6l6y

1926653

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/cfhzobufhffvbeeqnbm4vo6l6y

24 November 2022

mapped directly with Wikidata item

1926653

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference