An essential function for NBS1 in the prevention of ataxia and cerebellar defects (Q28507300)

6

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Pierre-Olivier Frappart

object named as

Pierre-Olivier Frappart

1

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author name string

Wei-Min Tong

2

1 reference

24 January 2017

Ivan Radovanovic

4

1 reference

24 January 2017

Zdenko Herceg

5

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24 January 2017

Martin Digweed

7

1 reference

24 January 2017

Zhao-Qi Wang

The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder

8

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24 January 2017

language of work or name

English

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publication date

1 May 2005

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24 January 2017

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24 January 2017

11

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24 January 2017

538–544

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24 January 2017

5

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24 January 2017

1 reference

Conditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells

21 April 2017

1 reference

Targeted disruption of NBS1 reveals its roles in mouse development and DNA repair

21 April 2017

1 reference

Checkpoint failure and chromosomal instability without lymphomagenesis in Mre11(ATLD1/ATLD1) mice

21 April 2017

1 reference

Ataxia telangiectasia mutated is essential during adult neurogenesis

21 April 2017

1 reference

To die or not to die: how does p53 decide?

21 April 2017

1 reference

A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis

21 April 2017

1 reference

Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development

21 April 2017

1 reference

Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV

21 April 2017

1 reference

DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway

21 April 2017

1 reference

A mouse model of episodic ataxia type-1

21 April 2017

1 reference

21 April 2017

1 reference

Atm-deficient mice: a paradigm of ataxia telangiectasia

21 April 2017

1 reference

Nijmegen breakage syndrome

21 April 2017

1 reference

Nijmegen breakage syndrome gene, NBS1, and molecular links to factors for genome stability

21 January 2018

1 reference

Ataxia-telangiectasia, an evolving phenotype

21 January 2018

1 reference

The Mre11 complex: at the crossroads of dna repair and checkpoint signalling

21 January 2018

1 reference

Targeted disruption of the Nijmegen breakage syndrome gene NBS1 leads to early embryonic lethality in mice.

21 January 2018

1 reference

A murine model of Nijmegen breakage syndrome

21 January 2018

1 reference

Failed clearance of aneuploid embryonic neural progenitor cells leads to excess aneuploidy in the Atm-deficient but not the Trp53-deficient adult cerebral cortex.

21 January 2018

1 reference

Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma

21 January 2018

1 reference

Abnormal development of Purkinje cells and lymphocytes in Atm mutant mice

21 January 2018

1 reference

Bypass of lethality with mosaic mice generated by Cre– loxP -mediated recombination

21 January 2018

1 reference

P53 and radiation responses

21 January 2018

1 reference

Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo.

21 January 2018

1 reference

ATM: genome stability, neuronal development, and cancer cross paths

21 January 2018

2 references

21 January 2018

inferred from DOI database lookup

7 January 2021

based on heuristic

An alternative mode of translation permits production of a variant NBS1 protein from the common Nijmegen breakage syndrome allele

1 reference

An inducible null mutant murine model of Nijmegen breakage syndrome proves the essential function of NBS1 in chromosomal stability and cell viability.

21 January 2018

1 reference

The cells and molecules that make a cerebellum.

21 January 2018

1 reference

ATM dependent apoptosis in the nervous system

21 January 2018

1 reference

The DNA double-strand break response in the nervous system

21 January 2018

1 reference

Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis.

21 January 2018

1 reference

Regulation of p53 in response to DNA damage

21 January 2018

1 reference

Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex

21 January 2018

1 reference

The Mre11 complex and the metabolism of chromosome breaks: the importance of communicating and holding things together

21 January 2018

1 reference