P53 and radiation responses (Q35208809)

7 August 2017

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title

P53 and radiation responses (English)

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7 August 2017

Peiwen Fei

1

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7 August 2017

Wafik S El-Deiry

series ordinal

2

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7 August 2017

language of work or name

English

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publication date

1 September 2003

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7 August 2017

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7 August 2017

22

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7 August 2017

5774-5783

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7 August 2017

37

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1206677

7 August 2017

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cites work

A p53-dependent S-phase checkpoint helps to protect cells from DNA damage in response to starvation for pyrimidine nucleotides

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

Up-regulation of Fas ligand expression by human cytomegalovirus immediate-early gene product 2: a novel mechanism in cytomegalovirus-induced apoptosis in human retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

Preparation and in vitro evaluation of slow release ketoprofen microcapsules formulated into tablets and capsules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

p53 regulates a G2 checkpoint through cyclin B1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

Wild-type p53 is a cell cycle checkpoint determinant following irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

Apoptotic threshold is lowered by p53 transactivation of caspase-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

Molecular determinants of radiosensitivity in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

Overexpression of the Bcl-2 protein increases the half-life of p21Bax

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

Radiosensitivity in ataxia-telangiectasia: a new explanation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

Sequence-specific transcriptional activation is essential for growth suppression by p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

Cell cycle control, checkpoint mechanisms, and genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

Functions of p53 suppress critical consequences of damage and repair in the initiation of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

GADD45 induction of a G2/M cell cycle checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

Further characterisation of the p53 responsive element--identification of new candidate genes for trans-activation by p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

Tissue and cell-specific expression of the p53-target genes: bax, fas, mdm2 and waf1/p21, before and following ionising irradiation in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

Tissue specific expression of p53 target genes suggests a key role for KILLER/DR5 in p53-dependent apoptosis in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

Thymocyte apoptosis induced by p53-dependent and independent pathways.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

DNA damage-induced cell cycle checkpoints and DNA strand break repair in development and tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

WAF1, a potential mediator of p53 tumor suppression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

Cell cycle checkpoints: preventing an identity crisis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

p53: a glimpse at the puppet behind the shadow play

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

Cdc25 Mitotic Inducer Targeted by Chk1 DNA Damage Checkpoint Kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

Protein synthesis required to anchor a mutant p53 protein which is temperature-sensitive for nuclear transport

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

Synergistic activation of transcription by CBP and p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

Checkpoints: controls that ensure the order of cell cycle events

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

p53 mutations in human cancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

The role of DNA double strand breaks in lonizing radiation-induced killing of eukaryotic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

GADD45-induced cell cycle G2-M arrest associates with altered subcellular distribution of cyclin B1 and is independent of p38 kinase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

The ability of p53 to activate downstream genes p21(WAF1/cip1) and MDM2, and cell cycle arrest following DNA damage is delayed and attenuated in scid cells deficient in the DNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

Transgenic mice with p53-responsive lacZ: p53 activity varies dramatically during normal development and determines radiation and drug sensitivity in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

Cancer. p53, guardian of the genome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

Promoter specificity and stability control of the p53-related protein p73

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

p53, the cellular gatekeeper for growth and division

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

Delayed Initiation of DNA Synthesis in Irradiated Human Diploid Cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

p53 is required for radiation-induced apoptosis in mouse thymocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

Negative control of p53 by Sir2alpha promotes cell survival under stress

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

Deacetylation of p53 modulates its effect on cell growth and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

Evidence of the involvement of p53 in gamma-radiation-induced DNA repair in human lymphoblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

Apoptosis in small intestinal epithelial from p53-null mice: evidence for a delayed, p53-independent G2/M-associated cell death after gamma-irradiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

Parc: a cytoplasmic anchor for p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

The onset of p53-dependent DNA repair or apoptosis is determined by the level of accumulated damaged DNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

When checkpoints fail

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

A model for p53-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

Defying death after DNA damage.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

The cellular response to p53: the decision between life and death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

Regulation of the G2/M transition by p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

Radiation-induced phosphorylation of Chk1 at S345 is associated with p53-dependent cell cycle arrest pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

Activation of p53 transcriptional activity requires ATM's kinase domain and multiple N-terminal serine residues of p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

53BP1, a mediator of the DNA damage checkpoint

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

Induction of the TRAIL receptor KILLER/DR5 in p53-dependent apoptosis but not growth arrest

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53-regulated protein Gadd45

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

The DNA damage response: putting checkpoints in perspective

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206677

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1206677

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Dimensions Publication ID

7 August 2017

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