A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis (Q28292871)

X-ray repair complementing defective repair in Chinese hamster cells 4

GOA release 2020-03-11

1 reference

Ligase IV, DNA, ATP-dependent

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

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Y Gao

1

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Y Sun

2

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K M Frank

3

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P Dikkes

4

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Y Fujiwara

5

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K J Seidl

6

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J M Sekiguchi

7

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G A Rathbun

8

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W Swat

9

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J Wang

10

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R T Bronson

11

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B A Malynn

12

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M Bryans

13

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C Zhu

14

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J Chaudhuri

15

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L Davidson

16

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R Ferrini

17

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T Stamato

18

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S H Orkin

19

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M E Greenberg

20

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F W Alt

Bcl-x and the regulation of survival in the immune system.

21

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language of work or name

English

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publication date

23 December 1998

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published in

Cell

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volume

95

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page(s)

891-902

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issue

7

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cites work

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Programmed cell death is a universal feature of embryonic and postnatal neuroproliferative regions throughout the central nervous system.

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Ku80 is required for immunoglobulin isotype switching

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Development of B cells in scid mice with immunoglobulin transgenes: implications for the control of V(D)J recombination

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Double strand break repair

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The recombination activating gene-1 (RAG-1) transcript is present in the murine central nervous system

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Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV

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Ku86 defines the genetic defect and restores X-ray resistance and V(D)J recombination to complementation group 5 hamster cell mutants

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Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV

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A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination

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Recent advances in understanding V(D)J recombination.

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Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells

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DNA ligase IV is essential for V(D)J recombination and DNA double-strand break repair in human precursor lymphocytes

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Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination

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Growth retardation and leaky SCID phenotype of Ku70-deficient mice.

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Saccharomyces cerevisiae LIF1: a function involved in DNA double-strand break repair related to mammalian XRCC4.

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Generation and analysis of interleukin-4 deficient mice

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Efficient in vivo manipulation of mouse genomic sequences at the zygote stage

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The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination

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Ku70: a candidate tumor suppressor gene for murine T cell lymphoma

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Genes in the RB pathway and their knockout in mice

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The scid defect affects the final step of the immunoglobulin VDJ recombinase mechanism

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Ku70 is required for late B cell development and immunoglobulin heavy chain class switching

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Bcl-2 gene family in the nervous system

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Molecular genetic characterization of XRCC4 function

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RAG-1-deficient mice have no mature B and T lymphocytes

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Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

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Neurogenesis in spinal cord of mouse: an autoradiographic analysis

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Requirement for Ku80 in growth and immunoglobulin V(D)J recombination

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Ku70 is required for DNA repair but not for T cell antigen receptor gene recombination In vivo

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A newly identified DNA ligase of Saccharomyces cerevisiae involved in RAD52-independent repair of DNA double-strand breaks

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7 January 2021

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

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The end-joining reaction in V(D)J recombination

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Isolation of cell cycle-dependent gamma ray-sensitive Chinese hamster ovary cell

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7 January 2021

Two methods for assaying DNA double-strand break repair in mammalian cells by asymmetric field inversion gel electrophoresis

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Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity

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7 January 2021

Identification of Saccharomyces cerevisiae DNA ligase IV: involvement in DNA double-strand break repair

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T cell receptor (TCR)-beta gene recombination: dissociation from cell cycle regulation and developmental progression during T cell ontogeny

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7 January 2021

Yeast DNA ligase IV mediates non-homologous DNA end joining

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Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates

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7 January 2021