Computational prediction and experimental verification of new MAP kinase docking sites and substrates including Gli transcription factors (Q28475319)

8

object named as

Pierre Baldi

0 references

author name string

Thomas C Whisenant

1

0 references

David T Ho

2

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Ryan W Benz

3

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Jeffrey S Rogers

4

0 references

Robyn M Kaake

5

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Elizabeth A Gordon

6

0 references

Lan Huang

PLOS Computational Biology

7

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language of work or name

English

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publication date

26 August 2010

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published in

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volume

6

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page(s)

e1000908

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issue

8

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copyright license

Creative Commons Attribution 4.0 International

start time

26 August 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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19 March 2017

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A conserved docking site in MEKs mediates high-affinity binding to MAP kinases and cooperates with a scaffold protein to enhance signal transmission

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19 March 2017

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Regulated interaction of protein kinase Cdelta with the heterogeneous nuclear ribonucleoprotein K protein

19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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A cytoplasmic inhibitor of the JNK signal transduction pathway

19 March 2017

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19 March 2017

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7 April 2017

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7 April 2017

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9 May 2017

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Characterization of cell cycle specific protein interaction networks of the yeast 26S proteasome complex by the QTAX strategy

29 September 2017

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29 September 2017

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Context-dependent regulation of the GLI code in cancer by HEDGEHOG and non-HEDGEHOG signals

29 September 2017

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Understanding protein phosphorylation on a systems level

29 September 2017

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29 September 2017

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The completion of the Mammalian Gene Collection (MGC).

29 September 2017

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29 September 2017

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Epidermal growth factor receptor signaling synergizes with Hedgehog/GLI in oncogenic transformation via activation of the MEK/ERK/JUN pathway

29 September 2017

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GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation

29 September 2017

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29 September 2017

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Phosphorylation of protein phosphatase 2Czeta by c-Jun NH2-terminal kinase at Ser92 attenuates its phosphatase activity

29 September 2017

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29 September 2017

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29 September 2017

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Understanding and exploiting substrate recognition by protein kinases

29 September 2017

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29 September 2017

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Substrate and docking interactions in serine/threonine protein kinases

29 September 2017

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29 September 2017

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Non-canonical activation of GLI transcription factors: implications for targeted anti-cancer therapy

29 September 2017

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Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways.

29 September 2017

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29 September 2017

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Fibroblast growth factor blocks Sonic hedgehog signaling in neuronal precursors and tumor cells.

29 September 2017

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MAP kinase pathways: the first twenty years

29 September 2017

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Uses for JNK: the many and varied substrates of the c-Jun N-terminal kinases

29 September 2017

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Mechanisms of MAPK signalling specificity

29 September 2017

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Heterogeneous nuclear ribonucleoprotein K is over expressed, aberrantly localised and is associated with poor prognosis in colorectal cancer

29 September 2017

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Analysis of mitogen-activated protein kinase activation and interactions with regulators and substrates

29 September 2017

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29 September 2017

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What you can learn from one gene: GLI3

29 September 2017

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Interaction of N-WASP with hnRNPK and its role in filopodia formation and cell spreading

29 September 2017

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29 September 2017

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GLI transcription factors: mediators of oncogenic Hedgehog signalling

29 September 2017

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The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions

29 September 2017

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hnRNP K: an HDM2 target and transcriptional coactivator of p53 in response to DNA damage

29 September 2017

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A MAPK/HNRPK pathway controls BCR/ABL oncogenic potential by regulating MYC mRNA translation

29 September 2017

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Substrate specificity of protein kinases and computational prediction of substrates

29 September 2017

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Hidden Markov Models, grammars, and biology: a tutorial

29 September 2017

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Kinomics: methods for deciphering the kinome

29 September 2017

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29 September 2017

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A conserved protein interaction network involving the yeast MAP kinases Fus3 and Kss1.

29 September 2017

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Glucocorticoid receptor-JNK interaction mediates inhibition of the JNK pathway by glucocorticoids.

29 September 2017

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Signalling specificity of Ser/Thr protein kinases through docking-site-mediated interactions

29 September 2017

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Docking sites on mitogen-activated protein kinase (MAPK) kinases, MAPK phosphatases and the Elk-1 transcription factor compete for MAPK binding and are crucial for enzymic activity

29 September 2017

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Modular structure of a docking surface on MAPK phosphatases

29 September 2017

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Regulation of MAP kinases by docking domains

29 September 2017

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Identification of new JNK substrate using ATP pocket mutant JNK and a corresponding ATP analogue.

29 September 2017

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ERK phosphorylation drives cytoplasmic accumulation of hnRNP-K and inhibition of mRNA translation

29 September 2017

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Applications of peptide arrays prepared by the SPOT-technology

29 September 2017

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The ternary complex factor Net contains two distinct elements that mediate different responses to MAP kinase signalling cascades

29 September 2017

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Docking domains and substrate-specificity determination for MAP kinases

29 September 2017

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29 September 2017

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29 September 2017

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Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase

29 September 2017

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Differential targeting of MAP kinases to the ETS-domain transcription factor Elk-1.

29 September 2017

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A structural basis for substrate specificities of protein Ser/Thr kinases: primary sequence preference of casein kinases I and II, NIMA, phosphorylase kinase, calmodulin-dependent kinase II, CDK5, and Erk1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928751

Hidden Markov models of biological primary sequence information

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928751

The K protein domain that recruits the interleukin 1-responsive K protein kinase lies adjacent to a cluster of c-Src and Vav SH3-binding sites. Implications that K protein acts as a docking platform

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928751

Oncogenic KRAS activates hedgehog signaling pathway in pancreatic cancer cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928751

Clustering of phosphorylation site recognition motifs can be exploited to predict the targets of cyclin-dependent kinase

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928751

Protein kinase C-delta and mitogen-activated protein/extracellular signal-regulated kinase-1 control GLI activation in hedgehog signaling

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928751

Dual degradation signals control Gli protein stability and tumor formation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928751

Cooperation between sonic hedgehog and fibroblast growth factor/MAPK signalling pathways in neocortical precursors

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928751

Signal transduction through MAP kinase cascades

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928751

The novel DNA glycosylase, NEIL1, protects mammalian cells from radiation-mediated cell death

2 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1000908

Hybrid modeling, HMM/NN architectures, and protein applications

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1000908

Docking sites on substrate proteins direct extracellular signal-regulated kinase to phosphorylate specific residues

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1000908

Protein modeling with hybrid Hidden Markov Model/neural network architectures.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928751

A profile hidden Markov model for signal peptides generated by HMMER

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20865152

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Regulation of the hedgehog signaling by the mitogen-activated protein kinase cascade in gastric cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20865152

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PCBI.1000908

1 reference

journals/ploscb/WhisenantHBRKGHBB10

2286728

DBLP publication ID

1 reference

DBLP Dataset 2021-01-02

28 January 2021

2286728

1 reference

1 reference

1 reference