Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory (Q28202553)

The gene encoding DRAP (BACE2), a glycosylated transmembrane protein of the aspartic protease family, maps to the down critical region

Europe PubMed Central

title

Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory (English)

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4

Wickliffe C Abraham

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Warren Tate

series ordinal

3

object named as

Warren P Tate

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author name string

Paul R Turner

series ordinal

1

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Kate O'Connor

series ordinal

2

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language of work or name

English

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publication date

May 2003

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published in

Progress in Neurobiology

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volume

70

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page(s)

1-32

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issue

1

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cites work

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A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

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7 January 2021

Demonstration by fluorescence resonance energy transfer of two sites of interaction between the low-density lipoprotein receptor-related protein and the amyloid precursor protein: role of the intracellular adapter protein Fe65.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Direct visualization of the gamma secretase-generated carboxyl-terminal domain of the amyloid precursor protein: association with Fe65 and translocation to the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

The gamma secretase-generated carboxyl-terminal domain of the amyloid precursor protein induces apoptosis via Tip60 in H4 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Glutamate-stimulated secretion of amyloid precursor protein from cortical rat brain slices.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Ontogenetic changes in protein level of amyloid precursor protein (APP) in growth cones and synaptosomes from rat brain and prenatal expression pattern of APP mRNA isoforms in developing rat embryo.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Targeting small Abeta oligomers: the solution to an Alzheimer's disease conundrum?

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Cell surface APP751 forms complexes with protease nexin 2 ligands and is internalized via the low density lipoprotein receptor-related protein (LRP).

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Membrane-anchored metalloprotease MDC9 has an alpha-secretase activity responsible for processing the amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Reversible memory loss in a mouse transgenic model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Altered synaptic plasticity in hippocampal CA1 area of apolipoprotein E deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Site-directed antisense oligonucleotide decreases the expression of amyloid precursor protein and reverses deficits in learning and memory in aged SAMP8 mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Decreased alpha-secretase-cleaved amyloid precursor protein as a diagnostic marker for Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Alterations in synaptic transmission and long-term potentiation in hippocampal slices from young and aged PDAPP mice

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Presenilin 1 is required for maturation and cell surface accumulation of nicastrin

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Candidate gene for the chromosome 1 familial Alzheimer's disease locus

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Neuronal-glial interactions mediated by interleukin-1 enhance neuronal acetylcholinesterase activity and mRNA expression.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Constitutive alpha-secretase cleavage of the beta-amyloid precursor protein in the furin-deficient LoVo cell line: involvement of the pro-hormone convertase 7 and the disintegrin metalloprotease ADAM10.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Comprehensive theory of Alzheimer's disease. The effects of cholesterol on membrane receptor trafficking.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Hippocampal injections of amyloid beta-peptide 1-40 impair subsequent one-trial/day reward learning.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

A novel carboxypeptidase B that processes native beta-amyloid precursor protein is present in human hippocampus

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

CNS synaptogenesis promoted by glia-derived cholesterol

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

The neurotoxicity of amyloid beta protein in aged primates.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Neuroplasticity failure in Alzheimer's disease: bridging the gap between plaques and tangles

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

A plasticity-based theory of the pathogenesis of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Memory-enhancing effects of secreted forms of the beta-amyloid precursor protein in normal and amnestic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Mitogen-activated protein kinase is involved in N-methyl-D-aspartate receptor regulation of amyloid precursor protein cleavage

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Expression and analysis of heparin-binding regions of the amyloid precursor protein of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Goprotein as signal transducer in the pertussis toxin-sensitive phosphatidylinositol pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Alzheimer's disease: beta-Amyloid protein and tau.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Beta-amyloid precursor polypeptide in SAMP8 mice affects learning and memory.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Antibody to amyloid beta protein alleviates impaired acquisition, retention, and memory processing in SAMP8 mice

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

The amyloid precursor protein is developmentally regulated and correlated with synaptogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Synaptotrophic effects of human amyloid β protein precursors in the cortex of transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Neurotrophic and neuroprotective effects of hAPP in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

The effect of age on the response of the rat brains to continuous beta-amyloid infusion.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Growth-associated protein GAP-43 is expressed selectively in associative regions of the adult human brain

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Alzheimer's disease: a re-examination of the amyloid hypothesis

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Synaptic activity modulates the induction of bidirectional synaptic changes in adult mouse hippocampus.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Alzheimer amyloid protein precursor complexes with brain GTP-binding protein G(o)

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Release of amyloid beta-protein precursor derivatives by electrical depolarization of rat hippocampal slices

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Metabotropic glutamate receptor subtype mGluR1alpha stimulates the secretion of the amyloid beta-protein precursor ectodomain.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Regulation of APP cleavage by alpha-, beta- and gamma-secretases

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Endogenous GLP-1 is involved in beta-amyloid protein-induced memory impairment and hippocampal neuronal death in rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Ligand-dependent G protein coupling function of amyloid transmembrane precursor

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Intrinsic signaling function of APP as a novel target of three V642 mutations linked to familial Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Reversible and irreversible acetylcholinesterase inhibitors cause changes in neuronal amyloid precursor protein processing and protein kinase C level in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Synaptic transmission and hippocampal long-term potentiation in transgenic mice expressing FAD-linked presenilin 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Alzheimer's amyloid precursor protein alpha-secretase is inhibited by hydroxamic acid-based zinc metalloprotease inhibitors: similarities to the angiotensin converting enzyme secretase

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Cleavage of Alzheimer's amyloid precursor protein by alpha-secretase occurs at the surface of neuronal cells

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

The beta-amyloid precursor protein of Alzheimer's disease enhances neuron viability and modulates neuronal polarity

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

beta-Amyloid(1-42) peptide directly modulates nicotinic receptors in the rat hippocampal slice.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

No hippocampal neuron or synaptic bouton loss in learning-impaired aged beta-amyloid precursor protein-null mice

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Aggregation of secreted amyloid beta-protein into sodium dodecyl sulfate-stable oligomers in cell culture

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Identification of a novel family of presenilin homologues

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

NMDA receptor regulation by amyloid-beta does not account for its inhibition of LTP in rat hippocampus

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: implications for Alzheimer's disease therapeutics

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Increase of synaptic density and memory retention by a peptide representing the trophic domain of the amyloid beta/A4 protein precursor

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Metalloprotease-disintegrin MDC9: intracellular maturation and catalytic activity

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Cell-specific expression of beta-amyloid precursor protein isoform mRNAs and proteins in neurons and astrocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Constitutive overactivation of protein kinase C in guinea pig brain increases alpha-secretory APP processing without decreasing beta-amyloid generation

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Nicotinic Stimulation of [3H]Acetylcholine Release from Mouse Cerebral Cortical Synaptosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Fe65 and the protein network centered around the cytosolic domain of the Alzheimer's beta-amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

SB203580, the p38 mitogen-activated protein kinase inhibitor blocks the inhibitory effect of beta-amyloid on long-term potentiation in the rat hippocampus

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Secreted forms of the amyloid-beta precursor protein are ligands for the class A scavenger receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Evidence That Intramolecular Associations between Presenilin Domains Are Obligatory for Endoproteolytic Processing

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Jun NH2-terminal kinase (JNK) interacting protein 1 (JIP1) binds the cytoplasmic domain of the Alzheimer's beta-amyloid precursor protein (APP).

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Intracellular maturation and localization of the tumour necrosis factor alpha convertase (TACE)

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Localization of Alzheimer beta A4 amyloid precursor protein at central and peripheral synaptic sites.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Mechanisms contributing to the deficits in hippocampal synaptic plasticity in mice lacking amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Normal and abnormal biology of the beta-amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Levels of alpha- and beta-secretase cleaved amyloid precursor protein in the cerebrospinal fluid of Alzheimer's disease patients

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Alzheimer's disease associated with mutations in presenilin 2 is rare and variably penetrant.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Localization of amyloid precursor protein in selective postsynaptic densities of rat cortical neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

One exon of the human LSF gene includes conserved regions involved in novel DNA-binding and dimerization motifs

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Beta-amyloid precursor protein cleavage by a membrane-bound protease

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Identification and transport of full-length amyloid precursor proteins in rat peripheral nervous system.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Gamma-secretase: never more enigmatic

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Alzheimer's disease and Abeta toxicity: from top to bottom

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Amyloid-beta aggregation: selective inhibition of aggregation in mixtures of amyloid with different chain lengths

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Generation of aggregated beta-amyloid in the rat hippocampus impairs synaptic transmission and plasticity and causes memory deficits

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Alzheimer's disease amyloid precursor protein on the surface of cortical neurons in primary culture co-localizes with adhesion patch components

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Amyloid precursor protein of Alzheimer's disease: evidence for a stable, full-length, trans-membrane pool in primary neuronal cultures.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Tissue-Specific expression of rat kininogen mRNAs

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Tissue-specific expression of three types of beta-protein precursor mRNA: enhancement of protease inhibitor-harboring types in Alzheimer's disease brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Environmental conditions influence hippocampus-dependent behaviours and brain levels of amyloid precursor protein in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Long-term depression in the adult hippocampus in vivo involves activation of extracellular signal-regulated kinase and phosphorylation of Elk-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Ultrastructural localization of amyloid protein precursor in the normal and postischemic gerbil brain

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

alpha- and beta-secretase: profound changes in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Amyloid beta -peptide inhibition of the PKA/CREB pathway and long-term potentiation: reversibility by drugs that enhance cAMP signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

The oligomerization of amyloid beta-protein begins intracellularly in cells derived from human brain

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Amyloid-beta oligomers: their production, toxicity and therapeutic inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

beta-Amyloid(1-42) binds to alpha7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer's disease pathology

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Amyloid peptide Abeta(1-42) binds selectively and with picomolar affinity to alpha7 nicotinic acetylcholine receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Soluble oligomers of beta amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Formation of stable complexes between two Alzheimer's disease gene products: presenilin-2 and beta-amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Requirement of the JIP1 scaffold protein for stress-induced JNK activation

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Plaques, tangles and dementia. A quantitative study.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Presenilins are not required for A beta 42 production in the early secretory pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Are presenilins intramembrane-cleaving proteases? Implications for the molecular mechanism of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

beta-Amyloid selectively augments NMDA receptor-mediated synaptic transmission in rat hippocampus.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Interaction between amyloid precursor protein and presenilins in mammalian cells: implications for the pathogenesis of Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

The mutation in amyloid precursor protein inhibits both alpha- and beta-secretion.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

G protein-mediated neuronal DNA fragmentation induced by familial Alzheimer's disease-associated mutants of APP.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Suppressive action produced by beta-amyloid peptide fragment 31-35 on long-term potentiation in rat hippocampus is N-methyl-D-aspartate receptor-independent: it's offset by (-)huperzine A

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Evidence that A beta 42 is the real culprit in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

APP processing and synaptic plasticity in presenilin-1 conditional knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Nicotine and its interaction with beta-amyloid protein: a short review

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

The Fe65 adaptor protein interacts through its PID1 domain with the transcription factor CP2/LSF/LBP1

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Activation of tumor necrosis factor-alpha-converting enzyme-mediated ectodomain shedding by nitric oxide

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Reactive oxygen species mediate tumor necrosis factor alpha-converting, enzyme-dependent ectodomain shedding induced by phorbol myristate acetate

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Amyloid beta peptide induces tau phosphorylation and loss of cholinergic neurons in rat primary septal cultures

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

Role of Tissue Plasminogen Activator Receptor LRP in Hippocampal Long-Term Potentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900089-3

7 January 2021

10.1016/S0301-0082(03)00089-3

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

3809522

3809522

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference