Immunomodulatory Function of the Tumor Suppressor p53 in Host Immune Response and the Tumor Microenvironment (Q28071935)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27869779%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

review article

3 references

8 February 2021

31 July 2022

Immunomodulatory Function of the Tumor Suppressor p53 in Host Immune Response and the Tumor Microenvironment (English)

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27869779%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

1 reference

20 December 2019

tumor microenvironment

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8 September 2020

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14 September 2020

neoplastic gene expression regulation

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4 November 2020

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21 December 2020

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8 February 2021

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27869779%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

author name string

Gang Guo

series ordinal

2

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27869779%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

language of work or name

1 reference

19 November 2016

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3 April 2019

8 September 2019

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28 November 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27869779%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

8 September 2020

14 September 2020

4 November 2020

5 December 2020

21 December 2020

8 February 2021

31 July 2022

International Journal of Molecular Sciences

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3 April 2019

8 September 2019

17 September 2019

28 November 2019

11 December 2019

18 December 2019

19 December 2019

20 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27869779%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

8 September 2020

14 September 2020

4 November 2020

5 December 2020

21 December 2020

8 February 2021

31 July 2022

17

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27869779%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

page(s)

1942

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issue

11

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27869779%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution

27 March 2020

copyright license

15 references

3 April 2019

8 September 2019

17 September 2019

28 November 2019

11 December 2019

18 December 2019

19 December 2019

20 December 2019

8 September 2020

14 September 2020

4 November 2020

5 December 2020

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8 February 2021

31 July 2022

0 references

on focus list of Wikimedia project

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IL-17 promotes tumor development through the induction of tumor promoting microenvironments at tumor sites and myeloid-derived suppressor cells

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Mutant p53 drives invasion by promoting integrin recycling

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Short-term inhibition of p53 combined with keratinocyte growth factor improves thymic epithelial cell recovery and enhances T-cell reconstitution after murine bone marrow transplantation

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Pharmacological activation of the p53 pathway in haematological malignancies

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Inflammation and cancer: interweaving microRNA, free radical, cytokine and p53 pathways

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IKK/NF-kappaB and STAT3 pathways: central signalling hubs in inflammation-mediated tumour promotion and metastasis

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29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133937

IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133937

The common mechanisms of transformation by the small DNA tumor viruses: The inactivation of tumor suppressor gene products: p53.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133937

p53 regulates Toll-like receptor 3 expression and function in human epithelial cell lines

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133937

Development of multi-epitope vaccines targeting wild-type sequence p53 peptides

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133937

The anticancer immune response: indispensable for therapeutic success?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133937

Immunological aspects of cancer chemotherapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133937

Genomic instability within tumor stroma and clinicopathological characteristics of sporadic primary invasive breast carcinoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133937

p53 alterations in human cancer: more questions than answers.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133937

Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133937

Modeling the therapeutic efficacy of p53 restoration in tumors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133937

p53 Attenuates cancer cell migration and invasion through repression of SDF-1/CXCL12 expression in stromal fibroblasts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133937

Immune resistance orchestrated by the tumor microenvironment

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133937

Stromal fibroblasts in cancer: a novel tumor-promoting cell type

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133937

The DNA damage response arouses the immune system

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133937

Lymphoid neogenesis in chronic inflammatory diseases.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133937

Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133937

The p53 tumor suppressor network is a key responder to microenvironmental components of chronic inflammatory stress.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133937

Role of Stat3 in regulating p53 expression and function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133937

Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133937

Regional analysis of p53 mutations in rheumatoid arthritis synovium

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133937

Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133937

Regulation of joint destruction and inflammation by p53 in collagen-induced arthritis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133937

Rheumatoid arthritis and p53: how oxidative stress might alter the course of inflammatory diseases.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133937

Sequential expression of protooncogenes during lectin-stimulated mitogenesis of normal human lymphocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133937

Multiple roles of p53-related pathways in somatic cell reprogramming and stem cell differentiation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133937

Increased p53 mutation load in noncancerous colon tissue from ulcerative colitis: a cancer-prone chronic inflammatory disease

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133937

SV40 T antigen abrogates p53-mediated transcriptional activity.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133937

p53 inactivation by HPV16 E6 results in increased mutagenesis in human cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133937

Differential regulation of the tumor suppressor molecules, retinoblastoma susceptibility gene product (Rb) and p53, during cell cycle progression of normal human T cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133937

MUT-TP53 2.0: a novel versatile matrix for statistical analysis of TP53 mutations in human cancer.

2 June 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS17111942

Trp53 inactivation in the tumor microenvironment promotes tumor progression by expanding the immunosuppressive lymphoid-like stromal network.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS17111942

p53 is a suppressor of inflammatory response in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS17111942

Evidence for nonautonomous effect of p53 tumor suppressor in carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS17111942

Gene transfer of p53 to arthritic joints stimulates synovial apoptosis and inhibits inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS17111942

Loss of p53 in enterocytes generates an inflammatory microenvironment enabling invasion and lymph node metastasis of carcinogen-induced colorectal tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS17111942

Peripheral antigen display by lymph node stroma promotes T cell tolerance to intestinal self

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS17111942

Inflammation recapitulates the ontogeny of lymphoid stromal cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS17111942

Selective evolution of stromal mesenchyme with p53 loss in response to epithelial tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS17111942

Activated p53 induces NF-kappaB DNA binding but suppresses its transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS17111942

p53 regulates glucose metabolism through an IKK-NF-kappaB pathway and inhibits cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS17111942

Breast-Cancer Stromal Cells withTP53Mutations and Nodal Metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS17111942

p53 tumor suppressor gene: at the crossroads of molecular carcinogenesis, molecular epidemiology, and human risk assessment.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133937

Regulatory role of p53 in experimental autoimmune encephalomyelitis

27 November 2018

1 reference

12 December 2020

Lymphoma development in Sjögren's syndrome: novel p53 mutations

1 reference

12 December 2020

Heterogeneity of stromal fibroblasts in tumors

1 reference

12 December 2020

Macrophage migration inhibitory factor: a probable link between inflammation and cancer

1 reference

12 December 2020

The MDM2 inhibitor Nutlin-3 modulates dendritic cell–induced T cell proliferation

1 reference

12 December 2020

Tumor suppressor p53 inhibits systemic autoimmune diseases by inducing regulatory T cells

1 reference

12 December 2020

Tumor suppressor p53 inhibits autoimmune inflammation and macrophage function.

1 reference

12 December 2020

Immunogenic cell death and cross-priming are reaching the clinical immunotherapy arena

1 reference

12 December 2020

TCR-mediated death of mature T lymphocytes occurs in the absence of p53

1 reference

12 December 2020

Identifiers

DOI

10.3390/IJMS17111942

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27869779%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27869779%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

2 references