Transcriptional control of human p53-regulated genes (Q29617650)

Europe PubMed Central

title

Transcriptional control of human p53-regulated genes (English)

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30 April 2017

author name string

Riley T

1

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30 April 2017

Sontag E

2

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30 April 2017

Chen P

3

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30 April 2017

Levine A

4

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30 April 2017

language of work or name

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30 April 2017

publication date

May 2008

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Nature Reviews Molecular Cell Biology

30 April 2017

published in

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volume

9

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page(s)

402-12

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issue

5

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NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription

30 April 2017

cites work

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The regulation of AMPK beta1, TSC2, and PTEN expression by p53: stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways

31 March 2020

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A transcriptionally active DNA-binding site for human p53 protein complexes

31 March 2020

1 reference

Definition of a consensus binding site for p53

31 March 2020

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Oncogenic forms of p53 inhibit p53-regulated gene expression

31 March 2020

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Further characterisation of the p53 responsive element--identification of new candidate genes for trans-activation by p53

31 March 2020

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p53 Binds and activates the xeroderma pigmentosum DDB2 gene in humans but not mice.

31 March 2020

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Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment.

31 March 2020

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Regulation of the human p21(waf1/cip1) gene promoter via multiple binding sites for p53 and the vitamin D3 receptor.

31 March 2020

1 reference

31 March 2020

Surfing the p53 network

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The P53 pathway: what questions remain to be explored?

31 March 2020

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p53, the cellular gatekeeper for growth and division

31 March 2020

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p53 and apoptosis: it's not just in the nucleus anymore

31 March 2020

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IL-6 rescues enterocytes from hemorrhage induced apoptosis in vivo and in vitro by a bcl-2 mediated mechanism

31 March 2020

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Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

31 March 2020

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The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis

31 March 2020

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The p53 pathway: positive and negative feedback loops

31 March 2020

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The coordinate regulation of the p53 and mTOR pathways in cells

31 March 2020

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The regulation of exosome secretion: a novel function of the p53 protein

31 March 2020

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Targets and mechanisms for the regulation of translation in malignant transformation

31 March 2020

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The ribosomal 5.8S RNA as a target site for p53 protein in cell differentiation and oncogenesis.

31 March 2020

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Translational control of gene expression: role of IRESs and consequences for cell transformation and angiogenesis

31 March 2020

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Cytoplasmic complex of p53 and eEF2

31 March 2020

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Repression of hsp90beta gene by p53 in UV irradiation-induced apoptosis of Jurkat cells

31 March 2020

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Regulation of the human hsp70 promoter by p53

31 March 2020

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Transcriptional activation of the human proliferating-cell nuclear antigen promoter by p53.

31 March 2020

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A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage

31 March 2020

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Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen

31 March 2020

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p53 tumor suppressor protein regulates the levels of huntingtin gene expression

31 March 2020

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p53 regulates maternal reproduction through LIF

31 March 2020

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Functional interaction between p53, the TATA-binding protein (TBP), andTBP-associated factors in vivo.

31 March 2020

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p53 transcriptional activation mediated by coactivators TAFII40 and TAFII60

31 March 2020

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Synergistic activation of transcription by CBP and p53

31 March 2020

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Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

31 March 2020

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p53-mediated repression of alpha-fetoprotein gene expression by specific DNA binding

31 March 2020

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p53 suppresses the activation of the Bcl-2 promoter by the Brn-3a POU family transcription factor

31 March 2020

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p53 binds and represses the HBV enhancer: an adjacent enhancer element can reverse the transcription effect of p53

31 March 2020

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Gain of function of mutant p53: the mutant p53/NF-Y protein complex reveals an aberrant transcriptional mechanism of cell cycle regulation

31 March 2020

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DNA damage promotes histone deacetylase 4 nuclear localization and repression of G2/M promoters, via p53 C-terminal lysines

31 March 2020

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Repression of new p53 targets revealed by ChIP on chip experiments.

31 March 2020

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Transcription repression of a CCAAT-binding transcription factor CBF/HSP70 by p53.

31 March 2020

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Direct p53 transcriptional repression: in vivo analysis of CCAAT-containing G2/M promoters.

31 March 2020

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p53 negatively regulates cdc2 transcription via the CCAAT-binding NF-Y transcription factor

31 March 2020

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p53 and its homologues, p63 and p73, induce a replicative senescence through inactivation of NF-Y transcription factor

31 March 2020

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Negative regulation of Chk2 expression by p53 is dependent on the CCAAT-binding transcription factor NF-Y.

31 March 2020

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Inhibition of cyclooxygenase-2 gene expression by p53.

31 March 2020

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p53 is a NF-Y- and p21-independent, Sp1-dependent repressor of cyclin B1 transcription

31 March 2020

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p53 represses CAAT enhancer-binding protein (C/EBP)-dependent transcription of the albumin gene. A molecular mechanism involved in viral liver infection with implications for hepatocarcinogenesis.

31 March 2020

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P53 down-regulates matrix metalloproteinase-1 by targeting the communications between AP-1 and the basal transcription complex

31 March 2020

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Wild-type p53 binds to the TATA-binding protein and represses transcription

31 March 2020

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Transcriptional repression by p53 involves molecular interactions distinct from those with the TATA box binding protein

31 March 2020

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Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a.

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Histone deacetylase 2 modulates p53 transcriptional activities through regulation of p53-DNA binding activity

31 March 2020

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p21/CDKN1A mediates negative regulation of transcription by p53.

31 March 2020

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Transcriptional repression of the anti-apoptotic survivin gene by wild type p53.

31 March 2020

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Transcriptional repression by p53 through direct binding to a novel DNA element

31 March 2020

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p53 regulates caveolin gene transcription, cell cholesterol, and growth by a novel mechanism

31 March 2020

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Acetylation of p53 augments its site-specific DNA binding both in vitro and in vivo

31 March 2020

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Regulation of p53 activity through lysine methylation

31 March 2020

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Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases

31 March 2020

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Efficient specific DNA binding by p53 requires both its central and C-terminal domains as revealed by studies with high-mobility group 1 protein

31 March 2020

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Comparative binding of p53 to its promoter and DNA recognition elements.

31 March 2020

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p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

31 March 2020

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p53-dependent transcriptional regulation of the APC promoter in colon cancer cells treated with DNA alkylating agents

31 March 2020

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Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer

31 March 2020

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Wild-type p53 adopts a 'mutant'-like conformation when bound to DNA.

31 March 2020

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Differential recognition of response elements determines target gene specificity for p53 and p63

31 March 2020

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Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

31 March 2020

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Differential transactivation by the p53 transcription factor is highly dependent on p53 level and promoter target sequence.

31 March 2020

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Atomic force microscopy reveals kinks in the p53 response element DNA

31 March 2020

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DNA sequence-dependent deformability deduced from protein-DNA crystal complexes

31 March 2020

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AMID is a p53-inducible gene downregulated in tumors

31 March 2020

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A polymorphic microsatellite that mediates induction of PIG3 by p53.

31 March 2020

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A conserved intronic response element mediates direct p53-dependent transcriptional activation of both the human and murine bax genes

31 March 2020

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Physical and functional interactions between members of the tumour suppressor p53 and the Sp families of transcription factors: importance for the regulation of genes involved in cell-cycle arrest and apoptosis

31 March 2020

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The tumor suppressor protein p53 requires a cofactor to activate transcriptionally the human BAX promoter

31 March 2020

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p53 oligomerization and DNA looping are linked with transcriptional activation

31 March 2020

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A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans

31 March 2020

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Silencing of the novel p53 target gene Snk/Plk2 leads to mitotic catastrophe in paclitaxel (taxol)-exposed cells

31 March 2020

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Interaction of p53 with its consensus DNA-binding site

31 March 2020

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p53 tagged sites from human genomic DNA.

31 March 2020

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p63 and p73 are required for p53-dependent apoptosis in response to DNA damage

31 March 2020

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A global map of p53 transcription-factor binding sites in the human genome

31 March 2020

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The p53MH algorithm and its application in detecting p53-responsive genes

31 March 2020

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A biophysical approach to transcription factor binding site discovery

31 March 2020

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Specificity, free energy and information content in protein-DNA interactions

31 March 2020

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Assessing computational tools for the discovery of transcription factor binding sites

31 March 2020

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Applied bioinformatics for the identification of regulatory elements

31 March 2020

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Maximum entropy modeling of short sequence motifs with applications to RNA splicing signals.

31 March 2020

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Hidden Markov models in computational biology. Applications to protein modeling

31 March 2020

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Profile hidden Markov models

31 March 2020

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DNA binding sites: representation and discovery

31 March 2020

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Sequence logos: a new way to display consensus sequences

31 March 2020

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=18431400

31 March 2020

Identifiers

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30 April 2017

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

1439076

1047902014

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1439076

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Consolidated OpenCitations Corpus – April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=18431400

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30 April 2017

Consolidated OpenCitations Corpus – April 2017