Purinergic regulation of the immune system (Q38753350)

6 September 2017

Purinergic regulation of the immune system (English)

1 reference

6 September 2017

Caglar Cekic

1

1 reference

PubMed ID

26922909

6 September 2017

Joel Linden

series ordinal

2

1 reference

6 September 2017

1 February 2016

1 reference

Nature Reviews Immunology

6 September 2017

1 reference

6 September 2017

16

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6 September 2017

177-192

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6 September 2017

3

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Formamide-based synthesis of nucleobases by metal(II) octacyanomolybdate(IV): implication in prebiotic chemistry.

6 September 2017

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Biology of purinergic signalling: its ancient evolutionary roots, its omnipresence and its multiple functional significance.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Signaling at purinergic P2X receptors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Structure-based approaches to ligands for G-protein-coupled adenosine and P2Y receptors, from small molecules to nanoconjugates.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Pannexin 1 channels mediate 'find-me' signal release and membrane permeability during apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

The P2X(7) receptor-pannexin connection to dye uptake and IL-1beta release

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Unexpected link between an antibiotic, pannexin channels and apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Raised tone reveals ATP as a sympathetic neurotransmitter in the porcine mesenteric arterial bed

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

P2Y12 ADP receptor-dependent tyrosine phosphorylation of proteins of 27 and 31 kDa in thrombin-stimulated human platelets

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

The role of P2Y(14) and other P2Y receptors in degranulation of human LAD2 mast cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

C3a modulates IL-1β secretion in human monocytes by regulating ATP efflux and subsequent NLRP3 inflammasome activation.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

ATP release from dying autophagic cells and their phagocytosis are crucial for inflammasome activation in macrophages

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Immune cell regulation by autocrine purinergic signalling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

A CD38/CD203a/CD73 ectoenzymatic pathway independent of CD39 drives a novel adenosinergic loop in human T lymphocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Distribution of ectonucleotidases in the rodent brain revisited

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Inosine binds to A3 adenosine receptors and stimulates mast cell degranulation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

The equilibrative nucleoside transporter family, SLC29

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

The concentrative nucleoside transporter family, SLC28

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Central role of Sp1-regulated CD39 in hypoxia/ischemia protection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Inhibition of the ATP-gated P2X7 receptor promotes axonal growth and branching in cultured hippocampal neurons.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

P2X receptors, sensory neurons and pain

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Extracellular ATP and other nucleotides-ubiquitous triggers of intercellular messenger release

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Pannexin 1, an ATP release channel, is activated by caspase cleavage of its pore-associated C-terminal autoinhibitory region

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Alanine-(87)-threonine polymorphism impairs signaling and internalization of the human P2Y11 receptor, when co-expressed with the P2Y1 receptor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

A selective high-affinity antagonist of the P2Y14 receptor inhibits UDP-glucose-stimulated chemotaxis of human neutrophils.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Identification of hypoxia-inducible factor HIF-1A as transcriptional regulator of the A2B adenosine receptor during acute lung injury.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Myeloid-derived suppressor cells contribute to A2B adenosine receptor-induced VEGF production and angiogenesis in a mouse melanoma model

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Distinct roles for the A2B adenosine receptor in acute and chronic stages of bleomycin-induced lung injury.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

The A2B adenosine receptor promotes Th17 differentiation via stimulation of dendritic cell IL-6

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Insights into thymic purine metabolism and adenosine deaminase deficiency revealed by transgenic mice overexpressing ecto-5'-nucleotidase (CD73).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

ATP-induced apoptosis of thymocytes is mediated by activation of P2 X 7 receptor and involves de novo ceramide synthesis and mitochondria

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Extracellular adenosine regulates naive T cell development and peripheral maintenance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Pannexin-1 hemichannel-mediated ATP release together with P2X1 and P2X4 receptors regulate T-cell activation at the immune synapse

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

P2 receptor mRNA expression profiles in human lymphocytes, monocytes and CD34+ stem and progenitor cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Extracellular purine metabolism and signaling of CD73-derived adenosine in murine Treg and Teff cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Activation of the COOH-terminal Src kinase (Csk) by cAMP-dependent protein kinase inhibits signaling through the T cell receptor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Adenosine regulates CD8 T-cell priming by inhibition of membrane-proximal T-cell receptor signalling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Inhibition of cytokine production and cytotoxic activity of human antimelanoma specific CD8+ and CD4+ T lymphocytes by adenosine-protein kinase A type I signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Receptor desensitization and blockade of the suppressive effects of prostaglandin E(2) and adenosine on the cytotoxic activity of human melanoma-infiltrating T lymphocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

The specific type IV phosphodiesterase inhibitor rolipram combined with adenosine reduces tumor necrosis factor-alpha-primed neutrophil oxidative activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Phosphodiesterase 4 inhibition in the treatment of psoriasis, psoriatic arthritis and other chronic inflammatory diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Selective inhibition of KCa3.1 channels mediates adenosine regulation of the motility of human T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Adenosine acts through A2 receptors to inhibit IL-2-induced tyrosine phosphorylation of STAT5 in T lymphocytes: role of cyclic adenosine 3',5'-monophosphate and phosphatases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Adenosine inhibits activation-induced T cell expression of CD2 and CD28 co-stimulatory molecules: role of interleukin-2 and cyclic AMP signaling pathways

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Fine tuning T lymphocytes: a role for the lipid phosphatase SHIP-1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Suppressors of cytokine signaling (SOCS) in T cell differentiation, maturation, and function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Adenosine-mediated inhibition of cytotoxic activity and cytokine production by IL-2/NKp46-activated NK cells: involvement of protein kinase A isozyme I (PKA I).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

ATP inhibits the generation and function of regulatory T cells through the activation of purinergic P2X receptors.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Mast cells counteract regulatory T-cell suppression through interleukin-6 and OX40/OX40L axis toward Th17-cell differentiation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Extracellular adenosine-mediated modulation of regulatory T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Autocrine adenosine signaling promotes regulatory T cell-mediated renal protection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

CD73 expression on extracellular vesicles derived from CD4+ CD25+ Foxp3+ T cells contributes to their regulatory function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Mesenchymal stromal cells up-regulate CD39 and increase adenosine production to suppress activated T-lymphocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Isolation of functional human regulatory T cells (Treg) from the peripheral blood based on the CD39 expression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

CD39/adenosine pathway is involved in AIDS progression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Expression of CD39 by human peripheral blood CD4+ CD25+ T cells denotes a regulatory memory phenotype.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Regulatory T cells negatively affect IL-2 production of effector T cells through CD39/adenosine pathway in HIV infection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Cytokine dependent and independent iNKT cell activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Synthetic glycolipid ligands for human iNKT cells as potential therapeutic agents for immunotherapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Natural killer T cell dysfunction in CD39-null mice protects against concanavalin A-induced hepatitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Adenosine A2A receptor activation reduces hepatic ischemia reperfusion injury by inhibiting CD1d-dependent NKT cell activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Regulation of lymphocyte function by adenosine

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Pulmonary natural killer T cells play an essential role in mediating hyperoxic acute lung injury

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Activation of iNKT cells by a distinct constituent of the endogenous glucosylceramide fraction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

NKT cells mediate pulmonary inflammation and dysfunction in murine sickle cell disease through production of IFN-gamma and CXCR3 chemokines

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

The activity of adenosine deaminase and the level of nitric oxide in spinal cord of methotrexate administered rats: protective effect of caffeic acid phenethyl ester

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

The A2aR adenosine receptor controls cytokine production in iNKT cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Preactivation of NKT cells with alpha-GalCer protects against hepatic ischemia-reperfusion injury in mouse by a mechanism involving IL-13 and adenosine A2A receptor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Adenosine A2A receptors induced on iNKT and NK cells reduce pulmonary inflammation and injury in mice with sickle cell disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Sickle cell vaso-occlusion causes activation of iNKT cells that is decreased by the adenosine A2A receptor agonist regadenoson

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Tumor cell death and ATP release prime dendritic cells and efficient anticancer immunity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Adenosine modulates HIF-1{alpha}, VEGF, IL-8, and foam cell formation in a human model of hypoxic foam cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Effect of A2B adenosine receptor gene ablation on adenosine-dependent regulation of proinflammatory cytokines

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Myeloid expression of adenosine A2A receptor suppresses T and NK cell responses in the solid tumor microenvironment

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

The adenosine-dependent angiogenic switch of macrophages to an M2-like phenotype is independent of interleukin-4 receptor alpha (IL-4Rα) signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Adenosine A2A receptor activation and macrophage-mediated experimental glomerulonephritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Adenosine suppresses activation of nuclear factor-kappaB selectively induced by tumor necrosis factor in different cell types

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Adenosine receptors control HIV-1 Tat-induced inflammatory responses through protein phosphatase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Induction of murine adenosine A(2A) receptor expression by LPS: analysis of the 5' upstream promoter.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

A feedback loop in PPARγ-adenosine A2A receptor signaling inhibits inflammation and attenuates lung damages in a mouse model of LPS-induced acute lung injury

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Lipopolysaccharide rapidly modifies adenosine receptor transcripts in murine and human macrophages: role of NF-kappaB in A(2A) adenosine receptor induction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Adenosine A2A Receptor Upregulation in Human PMNs Is Controlled by miRNA-214, miRNA-15, and miRNA-16

31 March 2020

2 references

https://api.crossref.org/works/10.1038%2FNRI.2016.4

31 March 2020

12 December 2020

Adenosine A3 receptors negatively regulate the engulfment-dependent apoptotic cell suppression of inflammation

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Dendritic cells tolerized with adenosine A₂AR agonist attenuate acute kidney injury

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Adenosine A2A receptor, a potential valuable target for controlling reoxygenated DCs-triggered inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Adenosine affects expression of membrane molecules, cytokine and chemokine release, and the T-cell stimulatory capacity of human dendritic cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Regulatory T cell-derived adenosine induces dendritic cell migration through the Epac-Rap1 pathway.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Adenosine slows migration of dendritic cells but does not affect other aspects of dendritic cell maturation.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Expression and function of adenosine receptors in human dendritic cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Role of adenosine receptors in regulating chemotaxis and cytokine production of plasmacytoid dendritic cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Adenosine receptors in regulation of dendritic cell differentiation and function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Modulation of murine dendritic cell function by adenine nucleotides and adenosine: involvement of the A(2B) receptor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Leishmania amazonensisimpairs DC function by inhibiting CD40 expression via A2Badenosine receptor activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

The A2B adenosine receptor impairs the maturation and immunogenicity of dendritic cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

HIF-dependent induction of adenosine receptor A2b skews human dendritic cells to a Th2-stimulating phenotype under hypoxia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Adenosine deaminase potentiates the generation of effector, memory, and regulatory CD4+ T cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

CD26, adenosine deaminase, and adenosine receptors mediate costimulatory signals in the immunological synapse.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Pollen metabolome analysis reveals adenosine as a major regulator of dendritic cell–primed TH cell responses

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Adenosine A2B receptor blockade slows growth of bladder and breast tumors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

An A2A adenosine receptor agonist, ATL313, reduces inflammation and improves survival in murine sepsis models

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

IL-17 and TNF-α sustain neutrophil recruitment during inflammation through synergistic effects on endothelial activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Therapeutic anti-inflammatory effects of myeloid cell adenosine receptor A2a stimulation in lipopolysaccharide-induced lung injury

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Cyclic AMP-dependent inhibition of human neutrophil oxidative activity by substituted 2-propynylcyclohexyl adenosine A(2A) receptor agonists

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Activation of A2A adenosine receptors inhibits expression of alpha 4/beta 1 integrin (very late antigen-4) on stimulated human neutrophils

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

The role of adenosine receptors A2A and A2B signaling in renal fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Blockade of A2B adenosine receptor reduces left ventricular dysfunction and ventricular arrhythmias 1 week after myocardial infarction in the rat model

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Increased adenosine contributes to penile fibrosis, a dangerous feature of priapism, via A2B adenosine receptor signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

PD 81,723, an allosteric enhancer of the A1 adenosine receptor, lowers the threshold for ischemic preconditioning in dogs

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Evidence that the acute phase of ischemic preconditioning does not require signaling by the A 2B adenosine receptor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Infarct-sparing effect of A2A-adenosine receptor activation is due primarily to its action on lymphocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Myocardial infarct-sparing effect of adenosine A2A receptor activation is due to its action on CD4+ T lymphocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

The infarct-sparing effect of IB-MECA against myocardial ischemia/reperfusion injury in mice is mediated by sequential activation of adenosine A3 and A 2A receptors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Improvement in microvascular reflow and reduction of infarct size with adenosine in patients undergoing primary coronary stenting

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Autoimmunity in CD73/Ecto-5'-nucleotidase deficient mice induces renal injury

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

A1 adenosine receptor allosteric enhancer PD-81723 protects against renal ischemia-reperfusion injury

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Kidney-specific reconstitution of the A1 adenosine receptor in A1 adenosine receptor knockout mice reduces renal ischemia-reperfusion injury

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

A1 adenosine receptor activation inhibits inflammation, necrosis, and apoptosis after renal ischemia-reperfusion injury in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Adenosine A(2A) receptor activation prevents progressive kidney fibrosis in a model of immune-associated chronic inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Adenosine A2A receptor activation attenuates inflammation and injury in diabetic nephropathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Extracellular adenine nucleotides inhibit the activation of human CD4+ T lymphocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Adora2b adenosine receptor signaling protects during acute kidney injury via inhibition of neutrophil-dependent TNF-α release

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

The reno-vascular A2B adenosine receptor protects the kidney from ischemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Acute and delayed renal protection against renal ischemia and reperfusion injury with A1 adenosine receptors.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

The adenosine 2A receptor agonist GW328267C improves lung function after acute lung injury in rats.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Activation of A1, A2A, or A3 adenosine receptors attenuates lung ischemia-reperfusion injury

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Signaling through the A2B adenosine receptor dampens endotoxin-induced acute lung injury

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

In vitro induction of T cells that are resistant to A2 adenosine receptor-mediated immunosuppression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Adenosine A2A receptor activation on CD4+ T lymphocytes and neutrophils attenuates lung ischemia-reperfusion injury

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Adenosine A2B receptor and hyaluronan modulate pulmonary hypertension associated with chronic obstructive pulmonary disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

A2B adenosine receptor expression by myeloid cells is proinflammatory in murine allergic-airway inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Cross-talk between G(s)- and G(q)-coupled pathways in regulation of interleukin-4 by A(2B) adenosine receptors in human mast cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Deletion of ADORA2B from myeloid cells dampens lung fibrosis and pulmonary hypertension

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Blockade of IL-6 Trans signaling attenuates pulmonary fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Effect of the purinergic inhibitor oxidized ATP in a model of islet allograft rejection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Oxidized ATP inhibits T-cell-mediated autoimmunity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

The development and immunosuppressive functions of CD4(+) CD25(+) FoxP3(+) regulatory T cells are under influence of the adenosine-A2A adenosine receptor pathway.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Extracellular adenosine regulates colitis through effects on lymphoid and nonlymphoid cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Cutting edge: Critical role for A2A adenosine receptors in the T cell-mediated regulation of colitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Activation of A2A adenosine receptor attenuates intestinal inflammation in animal models of inflammatory bowel disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Adenosine A₂A receptor agonist-mediated increase in donor-derived regulatory T cells suppresses development of graft-versus-host disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Adenosine 2A receptor is protective against renal injury in MRL/lpr mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

CD73 is required for efficient entry of lymphocytes into the central nervous system during experimental autoimmune encephalomyelitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Anti-inflammatory or proinflammatory effect of an adenosine receptor agonist on the Th17 autoimmune response is inflammatory environment-dependent

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Roles of the adenosine receptor and CD73 in the regulatory effect of γδ T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Both MC5r and A2Ar are required for protective regulatory immunity in the spleen of post-experimental autoimmune uveitis in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

A2A adenosine receptor signaling in lymphocytes and the central nervous system regulates inflammation during experimental autoimmune encephalomyelitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Blocking A2B adenosine receptor alleviates pathogenesis of experimental autoimmune encephalomyelitis via inhibition of IL-6 production and Th17 differentiation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Blockade of A2A receptors potently suppresses the metastasis of CD73+ tumors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Immunological mechanisms of the antitumor effects of supplemental oxygenation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Antimetastatic effects of blocking PD-1 and the adenosine A2A receptor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

A2aR antagonists: Next generation checkpoint blockade for cancer immunotherapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Enhancement of tumor immunotherapy by deletion of the A2A adenosine receptor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Adenosine Receptor 2A Blockade Increases the Efficacy of Anti-PD-1 through Enhanced Antitumor T-cell Responses

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Growth and metastasis of B16-F10 melanoma cells is not critically dependent on host CD73 expression in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Bone marrow-derived mesenchymal stromal cells harness purinergenic signaling to tolerize human Th1 cells in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Inhibition of T-cell proliferation by murine multipotent mesenchymal stromal cells is mediated by CD39 expression and adenosine generation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Ectonucleotidases CD39 and CD73 on OvCA cells are potent adenosine-generating enzymes responsible for adenosine receptor 2A-dependent suppression of T cell function and NK cell cytotoxicity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

CD73-generated adenosine restricts lymphocyte migration into draining lymph nodes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Cancer exosomes express CD39 and CD73, which suppress T cells through adenosine production.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Targeting CD73 and downstream adenosine receptor signaling in triple-negative breast cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

A2A adenosine receptor protects tumors from antitumor T cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Adenosine A2A receptors intrinsically regulate CD8+ T cells in the tumor microenvironment

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Melanoma progression despite infiltration by in vivo-primed TRP-2-specific T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

High-avidity T cells are preferentially tolerized in the tumor microenvironment

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

An adenosine-mediated signaling pathway suppresses prenylation of the GTPase Rap1B and promotes cell scattering

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Accelerated Tumor Progression in Mice Lacking the ATP Receptor P2X7

31 March 2020

2 references

https://api.crossref.org/works/10.1038%2FNRI.2016.4

31 March 2020

12 December 2020

Purines, purinergic receptors, and cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

A functional landscape of resistance to ALK inhibition in lung cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

A2 Adenosine Receptors in Neutrophils from Health Volunteers and Patients with Rheumatic Disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Pharmacological and biochemical characterization of purified A2a adenosine receptors in human platelet membranes by [3H]-CGS 21680 binding

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Adenosine receptors: therapeutic aspects for inflammatory and immune diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Canine mast cell adenosine receptors: cloning and expression of the A3 receptor and evidence that degranulation is mediated by the A2B receptor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Activation of the A(3) adenosine receptor suppresses superoxide production and chemotaxis of mouse bone marrow neutrophils

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Neutrophil A2A adenosine receptor inhibits inflammation in a rat model of meningitis: synergy with the type IV phosphodiesterase inhibitor, rolipram

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Brief Report: Methotrexate Prevents Wear Particle-Induced Inflammatory Osteolysis in Mice Via Activation of Adenosine A2A Receptor.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

The role of plasma adenosine deaminase in chemoattractant-stimulated oxygen radical production in neutrophils

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Detection of P2X purinergic receptors on human B lymphocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Activation of the P2X7 receptor induces the rapid shedding of CD23 from human and murine B cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

ATP induces P2X7 receptor-independent cytokine and chemokine expression through P2X1 and P2X3 receptors in murine mast cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

P2X4 receptors expressed on microglial cells in post-ischemic inflammation of brain ischemic injury

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Functional evidence for the expression of P2X1, P2X4 and P2X7 receptors in human lung mast cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Expression of P2X5 in lymphoid malignancies results in LRH-1-specific cytotoxic T-cell-mediated lysis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

A truncation variant of the cation channel P2RX5 is upregulated during T cell activation.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Blockade of murine T cell activation by antagonists of P2Y6 and P2X7 receptors.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Expression of P2X6 receptors in the enteric nervous system of the rat gastrointestinal tract

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Expression of P2X receptors on immune cells in the rat liver during postnatal development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

P2X7 receptor differentially couples to distinct release pathways for IL-1beta in mouse macrophage

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

TLR agonists stimulate Nlrp3-dependent IL-1β production independently of the purinergic P2X7 receptor in dendritic cells and in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

IL-1β production is dependent on the activation of purinergic receptors and NLRP3 pathway in human macrophages

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

The relative importance of the ADP receptors, P2Y12 and P2Y1, in thrombin-induced platelet activation.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

P2Y4 receptor-mediated pinocytosis contributes to amyloid beta-induced self-uptake by microglia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Distribution of P2Y receptor subtypes on haematopoietic cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Responses of macrophages to the danger signals released from necrotic cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

NAADP+ is an agonist of the human P2Y11 purinergic receptor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

ADP acting on P2Y13 receptors is a negative feedback pathway for ATP release from human red blood cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

Purinergic P2X receptors: structural models and analysis of ligand-target interaction.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.4

ADP-ribosylation of P2X7: a matter of life and death for regulatory T cells and natural killer T cells.

31 March 2020

1 reference

12 December 2020

Expression of ecto-adenosine deaminase and CD26 in human T cells triggered by the TCR-CD3 complex. Possible role of adenosine deaminase as costimulatory molecule

1 reference

12 December 2020

Selective A2A adenosine receptor activation reduces ischemia-reperfusion injury in rat kidney

1 reference

12 December 2020

A3 and P2Y2 receptors control the recruitment of neutrophils to the lungs in a mouse model of sepsis

1 reference

12 December 2020

The A3 adenosine receptor is the unique adenosine receptor which facilitates release of allergic mediators in mast cells

1 reference

12 December 2020

ALK inhibitors in non-small cell lung cancer: crizotinib and beyond

1 reference

12 December 2020

Characterization of human A(2B) adenosine receptors: radioligand binding, western blotting, and coupling to G(q) in human embryonic kidney 293 cells and HMC-1 mast cells

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRI.2016.4

1 reference

6 September 2017

1 reference

PubMed ID

26922909