Biochemical Analysis of Yeast Suppressor of Ty 4/5 (Spt4/5) Reveals the Importance of Nucleic Acid Interactions in the Prevention of RNA Polymerase II Arrest (Q27934868)

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English	Biochemical Analysis of Yeast Suppressor of Ty 4/5 (Spt4/5) Reveals the Importance of Nucleic Acid Interactions in the Prevention of RNA Polymerase II Arrest	scientific article

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scholarly article

1 reference

1 December 2016

Biochemical Analysis of Yeast Suppressor of Ty 4/5 (Spt4/5) Reveals the Importance of Nucleic Acid Interactions in the Prevention of RNA Polymerase II Arrest (English)

1 reference

1 December 2016

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Transcription elongation factor SPT5 YML010W

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GOA release 2020-03-11

Transcription elongation factor SPT4 YGR063C

1 reference

GOA release 2020-03-11

DNA-directed RNA polymerase II core subunit RPB2 YOR151C

1 reference

GOA release 2020-03-11

DNA-directed RNA polymerase II core subunit RPO21 YDL140C

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GOA release 2020-03-11

author name string

J Brooks Crickard

1

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Jianhua Fu

2

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Joseph C Reese

3

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language of work or name

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publication date

6 May 2016

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Journal of Biological Chemistry

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1 December 2016

291

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19

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9853-70

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describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4858988/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4858988/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Structural and biochemical insights into the DNA-binding mode of MjSpt4p:Spt5 complex at the exit tunnel of RNAPII

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

20 March 2017

The ratcheted and ratchetable structural states of RNA polymerase underlie multiple transcriptional functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

20 March 2017

Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

20 March 2017

The Spt4-Spt5 complex: a multi-faceted regulator of transcription elongation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

20 March 2017

Pol II CTD kinases Bur1 and Kin28 promote Spt5 CTR-independent recruitment of Paf1 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

20 March 2017

The transcription elongation factor Spt5 influences transcription by RNA polymerase I positively and negatively

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

20 March 2017

Yeast transcription elongation factor Spt5 associates with RNA polymerase I and RNA polymerase II directly.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

20 March 2017

The multifunctional Ccr4-Not complex directly promotes transcription elongation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

20 March 2017

Architecture of the RNA polymerase-Spt4/5 complex and basis of universal transcription processivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

20 March 2017

Structural basis of RNA polymerase II backtracking, arrest and reactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

20 March 2017

RNA polymerase and transcription elongation factor Spt4/5 complex structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

20 March 2017

Uniform transitions of the general RNA polymerase II transcription complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

20 March 2017

Spt4/5 stimulates transcription elongation through the RNA polymerase clamp coiled-coil motif

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

20 March 2017

The C-terminal repeat domain of Spt5 plays an important role in suppression of Rad26-independent transcription coupled repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

20 March 2017

Control of transcriptional elongation and cotranscriptional histone modification by the yeast BUR kinase substrate Spt5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

20 March 2017

Fcp1 directly recognizes the C-terminal domain (CTD) and interacts with a site on RNA polymerase II distinct from the CTD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

20 March 2017

CTD-dependent dismantling of the RNA polymerase II elongation complex by the pre-mRNA 3'-end processing factor, Pcf11.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

20 March 2017

Histone H2B ubiquitylation is associated with elongating RNA polymerase II

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

20 March 2017

Dual roles for Spt5 in pre-mRNA processing and transcription elongation revealed by identification of Spt5-associated proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

20 March 2017

Molecular evidence for a positive role of Spt4 in transcription elongation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

20 March 2017

RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

20 March 2017

Spt5 cooperates with human immunodeficiency virus type 1 Tat by preventing premature RNA release at terminator sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

20 March 2017

Structure and function of the human transcription elongation factor DSIF

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

20 March 2017

Evidence that P-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

20 March 2017

Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

20 March 2017

DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

20 March 2017

SPT5, an essential gene important for normal transcription in Saccharomyces cerevisiae, encodes an acidic nuclear protein with a carboxy-terminal repeat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

20 March 2017

Structure-function analysis of human Spt4: evidence that hSpt4 and hSpt5 exert their roles in transcriptional elongation as parts of the DSIF complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

20 March 2017

NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

20 March 2017

Transcription elongation factor SII (TFIIS) enables RNA polymerase II to elongate through a block to transcription in a human gene in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

20 March 2017

Distinction and relationship between elongation rate and processivity of RNA polymerase II in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

7 April 2017

Five intermediate complexes in transcription initiation by RNA polymerase II

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

7 April 2017

NusG Is a Sequence-specific RNA Polymerase Pause Factor That Binds to the Non-template DNA within the Paused Transcription Bubble

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

29 September 2017

Structures and Functions of the Multiple KOW Domains of Transcription Elongation Factor Spt5

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

29 September 2017

Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

29 September 2017

Ccr4-Not and TFIIS Function Cooperatively To Rescue Arrested RNA Polymerase II

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

29 September 2017

The Rpb4/7 module of RNA polymerase II is required for carbon catabolite repressor protein 4-negative on TATA (Ccr4-not) complex to promote elongation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

29 September 2017

RNA polymerase pausing and nascent-RNA structure formation are linked through clamp-domain movement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

29 September 2017

Insights into how Spt5 functions in transcription elongation and repressing transcription coupled DNA repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

29 September 2017

Cys-pair reporters detect a constrained trigger loop in a paused RNA polymerase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

29 September 2017

A nexus for gene expression-molecular mechanisms of Spt5 and NusG in the three domains of life

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

29 September 2017

The spt5 C-terminal region recruits yeast 3' RNA cleavage factor I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

29 September 2017

The β subunit gate loop is required for RNA polymerase modification by RfaH and NusG.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

29 September 2017

Functional analysis of Thermus thermophilus transcription factor NusG

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

29 September 2017

Interactions between DSIF (DRB sensitivity inducing factor), NELF (negative elongation factor), and the Drosophila RNA polymerase II transcription elongation complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

29 September 2017

E. coli NusG inhibits backtracking and accelerates pause-free transcription by promoting forward translocation of RNA polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

29 September 2017

Functional regions of the N-terminal domain of the antiterminator RfaH.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

29 September 2017

Phosphorylation of the transcription elongation factor Spt5 by yeast Bur1 kinase stimulates recruitment of the PAF complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

29 September 2017

Core structure of the yeast spt4-spt5 complex: a conserved module for regulation of transcription elongation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

29 September 2017

Analysis of factor interactions with RNA polymerase II elongation complexes using a new electrophoretic mobility shift assay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

29 September 2017

Single-molecule tracking of mRNA exiting from RNA polymerase II

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

29 September 2017

Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

29 September 2017

Functional topography of nascent RNA in elongation intermediates of RNA polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

29 September 2017

The unfolded protein response coordinates the production of endoplasmic reticulum protein and endoplasmic reticulum membrane

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

29 September 2017

Increased accommodation of nascent RNA in a product site on RNA polymerase II during arrest

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

29 September 2017

Escherichia coli NusG protein stimulates transcription elongation rates in vivo and in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

29 September 2017

DSIF contributes to transcriptional activation by DNA-binding activators by preventing pausing during transcription elongation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

2 June 2018

Studies on transcription of 3'-extended templates by mammalian RNA polymerase II. Parameters that affect the initiation and elongation reactions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858988

2 June 2018

A regulator of transcriptional elongation controls vertebrate neuronal development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.716001

21 January 2018

The recruitment of the Saccharomyces cerevisiae Paf1 complex to active genes requires a domain of Rtf1 that directly interacts with the Spt4-Spt5 complex

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https://api.crossref.org/works/10.1074%2FJBC.M116.716001

21 January 2018

The pST44 polycistronic expression system for producing protein complexes in Escherichia coli.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.716001

21 January 2018

Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.716001

21 January 2018

Stability, flexibility, and dynamic interactions of colliding RNA polymerase II elongation complexes

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https://api.crossref.org/works/10.1074%2FJBC.M116.716001

21 January 2018

RNA emerging from the active site of RNA polymerase II interacts with the Rpb7 subunit

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.716001

21 January 2018

The transcriptional regulator RfaH stimulates RNA chain synthesis after recruitment to elongation complexes by the exposed nontemplate DNA strand.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.716001

21 January 2018

The anchor-away technique: rapid, conditional establishment of yeast mutant phenotypes

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21 January 2018

Competing for the clamp: promoting RNA polymerase processivity and managing the transition from initiation to elongation

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https://api.crossref.org/works/10.1074%2FJBC.M116.716001

21 January 2018

Interactions between fission yeast mRNA capping enzymes and elongation factor Spt5.

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https://api.crossref.org/works/10.1074%2FJBC.M116.716001

21 January 2018

A Ratchet Mechanism of Transcription Elongation and Its Control

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21 January 2018

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21 January 2018

Elongation by Drosophila RNA polymerase II. Transcription of 3'-extended DNA templates.

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27 November 2018

The 8-nucleotide-long RNA:DNA hybrid is a primary stability determinant of the RNA polymerase II elongation complex

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12 December 2020

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A central role of the RNA polymerase trigger loop in active-site rearrangement during transcriptional pausing

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12 December 2020

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Studies of in vitro transcription by calf thymus RNA polymerase II using a novel duplex DNA template

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https://pubmed.ncbi.nlm.nih.gov/26945063

12 December 2020

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The Tudor tandem of 53BP1: a new structural motif involved in DNA and RG-rich peptide binding

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12 December 2020

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