Transcription elongation factor SPT4 YGR063C (Q27553019)

RNA polymerase subunit RPABC4/transcription elongation factor Spt4

1 reference

Spt4 superfamily

1 reference

Spt4/RpoE2 zinc finger, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

RNA polymerase II elongation factors Spt4p and Spt5p play roles in transcription elongation by RNA polymerase I and rRNA processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32914

zinc ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32914

1 reference

14 February 2019

RNA polymerase II complex binding

1 reference

5 June 2018

Biochemical Analysis of Yeast Suppressor of Ty 4/5 (Spt4/5) Reveals the Importance of Nucleic Acid Interactions in the Prevention of RNA Polymerase II Arrest

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32914&geneProductId=UniProtKB:P32914

RNA polymerase I general transcription initiation factor activity

IC

1 reference

14 February 2019

RNA polymerase II elongation factors Spt4p and Spt5p play roles in transcription elongation by RNA polymerase I and rRNA processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32914

IC

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32914

1 reference

14 February 2019

single-stranded RNA binding

1 reference

5 June 2018

The yeast transcription elongation factor Spt4/5 is a sequence-specific RNA binding protein

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32914&geneProductId=UniProtKB:P32914

protein binding

7 references

14 February 2019

RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32914

14 February 2019

Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32914

14 February 2019

Core structure of the yeast spt4-spt5 complex: a conserved module for regulation of transcription elongation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32914

14 February 2019

A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32914

14 February 2019

A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32914

14 February 2019

Proteome survey reveals modularity of the yeast cell machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32914

14 February 2019

Functional Dissection of Yeast Hir1p, a WD Repeat–Containing Transcriptional Corepressor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32914

DNA-binding transcription factor activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32914&geneProductId=UniProtKB:P32914

1 reference

5 June 2018

protein-containing complex binding

IBA

1 reference

14 February 2019

Biochemical Analysis of Yeast Suppressor of Ty 4/5 (Spt4/5) Reveals the Importance of Nucleic Acid Interactions in the Prevention of RNA Polymerase II Arrest

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32914

RNA polymerase II complex binding

IBA

single-stranded RNA binding

1 reference

5 June 2018

Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32914&geneProductId=UniProtKB:P32914

chromosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32914

1 reference

14 February 2019

nucleus

2 references

kinetochore

1 reference

14 February 2019

Functional roles for evolutionarily conserved Spt4p at centromeres and heterochromatin in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32914

mating-type region heterochromatin

1 reference

14 February 2019

Functional roles for evolutionarily conserved Spt4p at centromeres and heterochromatin in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32914

rDNA heterochromatin

1 reference

14 February 2019

RNA polymerase II elongation factors Spt4p and Spt5p play roles in transcription elongation by RNA polymerase I and rRNA processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32914

chromosome, centromeric region

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32914

1 reference

14 February 2019

DSIF complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32914

1 reference

14 February 2019

chromosome segregation

1 reference

14 February 2019

Faithful chromosome transmission requires Spt4p, a putative regulator of chromatin structure in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32914

positive regulation of transcription elongation from RNA polymerase II promoter

positive regulation of DNA-templated transcription, elongation

2 references

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32914

1 reference

14 February 2019

transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32914&geneProductId=UniProtKB:P32914

1 reference

5 June 2018

7-methylguanosine mRNA capping

1 reference

14 February 2019

Dual roles for Spt5 in pre-mRNA processing and transcription elongation revealed by identification of Spt5-associated proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32914

positive regulation of transcription elongation from RNA polymerase I promoter

1 reference

14 February 2019

RNA polymerase II elongation factors Spt4p and Spt5p play roles in transcription elongation by RNA polymerase I and rRNA processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32914

chromatin organization

1 reference

5 June 2018

Functional roles for evolutionarily conserved Spt4p at centromeres and heterochromatin in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32914&geneProductId=UniProtKB:P32914

negative regulation of transcription elongation by RNA polymerase I

1 reference

14 February 2019

The Transcription Elongation Factor Spt5 Influences Transcription by RNA Polymerase I Positively and Negatively

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32914

intracellular mRNA localization

1 reference

14 February 2019

Cotranscriptional recruitment of She2p by RNA pol II elongation factor Spt4-Spt5/DSIF promotes mRNA localization to the yeast bud.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32914

regulation of transcription-coupled nucleotide-excision repair

1 reference

14 February 2019

The C-terminal repeat domain of Spt5 plays an important role in suppression of Rad26-independent transcription coupled repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32914

regulation of rRNA processing

1 reference

14 February 2019

A functional interface at the rDNA connects rRNA synthesis, pre-rRNA processing and nucleolar surveillance in budding yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32914

mRNA splicing, via spliceosome

1 reference

14 February 2019

Dual roles for Spt5 in pre-mRNA processing and transcription elongation revealed by identification of Spt5-associated proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32914

chromatin organization

IBA

transcription by RNA polymerase I

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32914

has part(s)

Spt4/RpoE2 zinc finger

1 reference

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference