Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation (Q24633548)

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Molecular Insights into the Function of RING Finger (RNF)-containing Proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent Ubiquitylation

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English	Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation	scientific article	Molecular Insights into the Function of RING Finger (RNF)-containing Proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent Ubiquitylation

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Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation (English)

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Stephen J Campbell

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Ross A Edwards

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Charles C Y Leung

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J N Mark Glover

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Sirano Dhe-Paganon

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15 May 2012

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Journal of Biological Chemistry

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23900-23910

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1 February 2020

Differential regulation of RNF8-mediated Lys48- and Lys63-based poly-ubiquitylation

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7 April 2017

Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1

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7 April 2017

PHENIX: a comprehensive Python-based system for macromolecular structure solution

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7 April 2017

HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes

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7 April 2017

RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins

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7 April 2017

The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage

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7 April 2017

Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase

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7 April 2017

RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly

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7 April 2017

RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

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7 April 2017

CCDC98 targets BRCA1 to DNA damage sites

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7 April 2017

Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response

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7 April 2017

Crystal structure of the ubiquitin binding domains of rabex-5 reveals two modes of interaction with ubiquitin

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MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks

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7 April 2017

Chaperoned ubiquitylation--crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex

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7 April 2017

Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13

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7 April 2017

Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair

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7 April 2017

Identification and preliminary characterization of a protein motif related to the zinc finger

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7 April 2017

The mechanism of OTUB1-mediated inhibition of ubiquitination

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7 April 2017

OTUB1 Co-opts Lys48-Linked Ubiquitin Recognition to Suppress E2 Enzyme Function

1 reference

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7 April 2017

Mechanism of ubiquitylation by dimeric RING ligase RNF4

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7 April 2017

E3 ligase Rad18 promotes monoubiquitination rather than ubiquitin chain formation by E2 enzyme Rad6

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7 April 2017

Crystal structure of UbcH5b~ubiquitin intermediate: insight into the formation of the self-assembled E2~Ub conjugates

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7 April 2017

Insights into Ubiquitin Transfer Cascades from a Structure of a UbcH5B∼Ubiquitin-HECTNEDD4L Complex

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7 April 2017

The structure of the UbcH8-ubiquitin complex shows a unique ubiquitin interaction site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390666

7 April 2017

Structural basis for specific recognition of Lys 63-linked polyubiquitin chains by tandem UIMs of RAP80

1 reference

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7 April 2017

E2 interaction and dimerization in the crystal structure of TRAF6

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7 April 2017

Structure of a conjugating enzyme-ubiquitin thiolester intermediate reveals a novel role for the ubiquitin tail

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7 April 2017

Structure of a BRCA1-BARD1 heterodimeric RING-RING complex

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7 April 2017

Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubc13 heterodimer

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7 April 2017

Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

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7 April 2017

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27 September 2017

The DNA Damage Response: Making It Safe to Play with Knives

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7 April 2017

Molecular replacement with MOLREP

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7 April 2017

Solving structures of protein complexes by molecular replacement with Phaser

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7 April 2017

Refinement of macromolecular structures by the maximum-likelihood method

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7 April 2017

Use of TLS parameters to model anisotropic displacements in macromolecular refinement

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7 April 2017

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27 September 2017

An NMR-based model of the ubiquitin-bound human ubiquitin conjugation complex Mms2.Ubc13. The structural basis for lysine 63 chain catalysis

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7 April 2017

Mms2-Ubc13 covalently bound to ubiquitin reveals the structural basis of linkage-specific polyubiquitin chain formation

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7 April 2017

More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance

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ARP/wARP and molecular replacement: the next generation

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27 September 2017

Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage

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27 September 2017

CCDC98 is a BRCA1-BRCT domain-binding protein involved in the DNA damage response

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27 September 2017

Structural basis for ubiquitin recognition and autoubiquitination by Rabex-5.

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27 September 2017

Sensitivity and selectivity of the DNA damage sensor responsible for activating p53-dependent G1 arrest

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27 September 2017

Noncovalent interaction between ubiquitin and the human DNA repair protein Mms2 is required for Ubc13-mediated polyubiquitination

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Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants

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The RING finger protein RNF8 recruits UBC13 for lysine 63-based self polyubiquitylation

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Detection of sequential polyubiquitylation on a millisecond timescale

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10.1074/JBC.M112.359653

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Consolidated OpenCitations Corpus – April 2017

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