Highlight: BRCA1 and BRCA2 proteins in breast cancer (Q24307401)

Microscopy Research and Technique

Europe PubMed Central

title

Highlight: BRCA1 and BRCA2 proteins in breast cancer (English)

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author name string

Dianne C Daniel

series ordinal

1

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language of work or name

English

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publication date

1 October 2002

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published in

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volume

59

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issue

1

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page(s)

68-83

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cites work

BRCA1 expression restores radiation resistance in BRCA1-defective cancer cells through enhancement of transcription-coupled DNA repair

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p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts

21 January 2018

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Heregulin induces phosphorylation of BRCA1 through phosphatidylinositol 3-Kinase/AKT in breast cancer cells

21 January 2018

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BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A

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Genetic susceptibility for breast cancer--risk assessment and counseling

21 January 2018

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BRCA1-associated growth arrest is RB-dependent

21 January 2018

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Tumor suppressor p53 is required to modulate BRCA1 expression

21 January 2018

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With the ends in sight: images from the BRCA1 tumor suppressor.

21 January 2018

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The BRCA1/BARD1 heterodimer, a tumor suppressor complex with ubiquitin E3 ligase activity

21 January 2018

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https://api.crossref.org/works/10.1002%2FJEMT.10178

Ras-induced colony formation and anchorage-independent growth inhibited by elevated expression of Puralpha in NIH3T3 cells.

21 January 2018

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https://api.crossref.org/works/10.1002%2FJEMT.10178

Synergistic actions of Rad51 and Rad52 in recombination and DNA repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Overexpression of BRCA2 gene in sporadic breast tumours.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Molecular profiling of breast cancer: portraits but not physiognomy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Structure of a BRCA1-BARD1 heterodimeric RING-RING complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Mammalian DNA mismatch repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Stabilization and activation of p53 by the coactivator protein TAFII31

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Reversal of terminal differentiation and control of DNA replication: cyclin A and Cdk2 specifically localize at subnuclear sites of DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

The second BRCT domain of BRCA1 proteins interacts with p53 and stimulates transcription from the p21WAF1/CIP1 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

The influence of familial and hereditary factors on the prognosis of breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Germline BRCA1/2 mutations and p27(Kip1) protein levels independently predict outcome after breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Clinico-pathological characteristics of BRCA1- and BRCA2-related breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Absence of methylation of CpG dinucleotides within the promoter of the breast cancer susceptibility gene BRCA2 in normal tissues and in breast and ovarian cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Mre11 protein complex prevents double-strand break accumulation during chromosomal DNA replication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Growth retardation, DNA repair defects, and lack of spermatogenesis in BRCA1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Dual immunofluorescence labeling with cell-specific markers localizes BRCA1 in both basal and luminal epithelial cells in primary outgrowth from noncancerous mammary ductal and alveolar preparations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Role of BRCA2 in control of the RAD51 recombination and DNA repair protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Distinct roles for E2F proteins in cell growth control and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Role of the tumor suppressor gene Brca1 in genetic stability and mammary gland tumor formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Structure and ligand of a histone acetyltransferase bromodomain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

BRG-1 is recruited to estrogen-responsive promoters and cooperates with factors involved in histone acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Decreased expression of BRCA2 mRNA predicts favorable response to docetaxel in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Repair of double-strand breaks by homologous recombination in mismatch repair-defective mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

p53 induction of heparin-binding EGF-like growth factor counteracts p53 growth suppression through activation of MAPK and PI3K/Akt signaling cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

21 January 2018

RING for destruction?

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

BRCA2 associates with acetyltransferase activity when bound to P/CAF

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

BRCA1 mutations in primary breast and ovarian carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

BRCA1 required for transcription-coupled repair of oxidative DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

hMSH2-hMSH6 forms a hydrolysis-independent sliding clamp on mismatched DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

DNA recombination: the replication connection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Recombination: a frank view of exchanges and vice versa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Linkage of early-onset familial breast cancer to chromosome 17q21

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Molecular mechanisms underlying ErbB2/HER2 action in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Rb function in cell-cycle regulation and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Gene-Expression Profiles in Hereditary Breast Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Protein regulation by monoubiquitin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Breast cancer: hormones and other risk factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

In vitro repression of Brca1-associated RING domain gene, Bard1, induces phenotypic changes in mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Cell cycle-dependent colocalization of BARD1 and BRCA1 proteins in discrete nuclear domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

BRCA1 activation of the GADD45 promoter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Sister chromatid gene conversion is a prominent double-strand break repair pathway in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Evidence for involvement of yeast proliferating cell nuclear antigen in DNA mismatch repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Apoptosis: a link between cancer genetics and chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Clinical management of BRCA1- and BRCA2-associated breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

DNA double strand break repair in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Protein-PCNA interactions: a DNA-scanning mechanism?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

New complexities for BRCA1 and BRCA2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

DNA double-strand breaks: signaling, repair and the cancer connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Tamoxifen and breast cancer incidence among women with inherited mutations in BRCA1 and BRCA2: National Surgical Adjuvant Breast and Bowel Project (NSABP-P1) Breast Cancer Prevention Trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

The BARD1-CstF-50 interaction links mRNA 3' end formation to DNA damage and tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Mammalian ubiquitin-conjugating enzyme Ubc9 interacts with Rad51 recombination protein and localizes in synaptonemal complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Molecular genetics of solid tumours: translating research into clinical practice. What we could do now: breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

BRCA2 mutations in primary breast and ovarian cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Radiation down-regulates replication origin activity throughout the S phase in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Mitotic checkpoint inactivation fosters transformation in cells lacking the breast cancer susceptibility gene, Brca2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

c-Cbl is a suppressor of the neu oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Binding of CtIP to the BRCT repeats of BRCA1 involved in the transcription regulation of p21 is disrupted upon DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Regulation of double-strand break-induced mammalian homologous recombination by UBL1, a RAD51-interacting protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

ATM binds to beta-adaptin in cytoplasmic vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Essential role of BETA2/NeuroD1 in development of the vestibular and auditory systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

CpG methylation within the 5' regulatory region of the BRCA1 gene is tumor specific and includes a putative CREB binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

SUMO-1 conjugation to human DNA topoisomerase II isozymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

SUMO-1 conjugation to topoisomerase I: A possible repair response to topoisomerase-mediated DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

BRCA1 suppresses insulin-like growth factor-I receptor promoter activity: potential interaction between BRCA1 and Sp1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

BRCA1 expression is not directly responsive to estrogen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

The BRCA2 gene product functionally interacts with p53 and RAD51

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

A human BRCA2 complex containing a structural DNA binding component influences cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Mre11 complex and DNA replication: linkage to E2F and sites of DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Mdm2-SUMO1: is bigger better?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

A mechanism for Rb/p130-mediated transcription repression involving recruitment of the CtBP corepressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Genes, chromatin, and breast cancer: an epigenetic tale

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

The BRCA2 activation domain associates with and is phosphorylated by a cellular protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

DNA damage-dependent nuclear dynamics of the Mre11 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Ubiquitination of RNA polymerase II large subunit signaled by phosphorylation of carboxyl-terminal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

BRCA1: exploring the links to transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Evidence for a transcriptional activation function of BRCA1 C-terminal region

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Brca1 controls homology-directed DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

BRCA2 is required for homology-directed repair of chromosomal breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

When the SWI/SNF complex remodels...the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

SUMO, ubiquitin's mysterious cousin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Breast cancer genetics: what we know and what we need

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

The Rb/E2F pathway and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Casein kinase 2 binds to and phosphorylates BRCA1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

BRCA1 regulates p53-dependent gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-gamma target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Preferential allelic expression can lead to reduced expression of BRCA1 in sporadic breast cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

CBP/p300 interact with and function as transcriptional coactivators of BRCA1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

21 January 2018

BRCA1 at a branch point

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Involvement of Brca2 in DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Direct DNA binding by Brca1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Breast carcinomas arising in carriers of mutations in BRCA1 or BRCA2: are they prognostically different?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Mechanisms underlying ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

THE GENETICS OF BREAST CANCER SUSCEPTIBILITY

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Ultraviolet radiation-induced ubiquitination and proteasomal degradation of the large subunit of RNA polymerase II. Implications for transcription-coupled DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Transcriptional repression of BRCA1 by aberrant cytosine methylation, histone hypoacetylation and chromatin condensation of the BRCA1 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Aberrant methylation of the BRCA1 CpG island promoter is associated with decreased BRCA1 mRNA in sporadic breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Megabase chromatin domains involved in DNA double-strand breaks in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

BRCA1 is a cell cycle-regulated nuclear phosphoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

BRCA1 is phosphorylated at serine 1497 in vivo at a cyclin-dependent kinase 2 phosphorylation site

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Cancer-predisposing mutations within the RING domain of BRCA1: loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Rad23 links DNA repair to the ubiquitin/proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Interactions between BRCA proteins and DNA structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

In search of the tumour-suppressor functions of BRCA1 and BRCA2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

DNA polymerase stalling, sister chromatid recombination and the BRCA genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Signaling networks that link cell proliferation and cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Identification of components of the murine histone deacetylase 6 complex: link between acetylation and ubiquitination signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Multiple functions of p27(Kip1) and its alterations in tumor cells: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Associations of UBE2I with RAD52, UBL1, p53, and RAD51 proteins in a yeast two-hybrid system

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

UBL1, a human ubiquitin-like protein associating with human RAD51/RAD52 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

ATM and ATR: networking cellular responses to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Allele losses in the region 17q12-21 in familial breast and ovarian cancer involve the wild-type chromosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

BRCA1 deficient embryonic stem cells display a decreased homologous recombination frequency and an increased frequency of non-homologous recombination that is corrected by expression of a brca1 transgene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

BRCA1 signals ARF-dependent stabilization and coactivation of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Truncated BRCA2 is cytoplasmic: implications for cancer-linked mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Role of covalent modifications of histones in regulating gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Acetylation of histones and transcription-related factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

The language of covalent histone modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Constitutive expression of the cyclin-dependent kinase inhibitor p21 is transcriptionally regulated by the tumor suppressor protein p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Regulation of the G2/M transition by p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

An important role for BRCA1 in breast cancer progression is indicated by its loss in a large proportion of non-familial breast cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

RING finger mutations that abolish c-Cbl-directed polyubiquitination and downregulation of the EGF receptor are insufficient for cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Gene expression profiling predicts clinical outcome of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Assessment of the need and appropriate method for testing for the human epidermal growth factor receptor-2 (HER2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Chromosome stability, DNA recombination and the BRCA2 tumour suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Cancer susceptibility and the functions of BRCA1 and BRCA2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

BRCA1 proteins are transported to the nucleus in the absence of serum and splice variants BRCA1a, BRCA1b are tyrosine phosphoproteins that associate with E2F, cyclins and cyclin dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

BRCA1 binds c-Myc and inhibits its transcriptional and transforming activity in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Regulation of BRCA1 expression by the Rb-E2F pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

21 January 2018

BRCA1 and cell signaling

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Adenosine nucleotide modulates the physical interaction between hMSH2 and BRCA1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

The retinoblastoma protein and cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Themes and variations on ubiquitylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

BRCA1 and BRCA2 and the genetics of breast and ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Insights into the functions of BRCA1 and BRCA2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Predicting the clinical status of human breast cancer by using gene expression profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Crystal structure of the BRCT repeat region from the breast cancer-associated protein BRCA1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Localization of human BRCA1 and its loss in high-grade, non-inherited breast carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

RAD51 interacts with the evolutionarily conserved BRC motifs in the human breast cancer susceptibility gene brca2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Characterization of a carboxy-terminal BRCA1 interacting protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Regulation of p53 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Identification of the breast cancer susceptibility gene BRCA2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Identification of a RING protein that can interact in vivo with the BRCA1 gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Effect of DNA damage on a BRCA1 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

mdm2: a bridge over the two tumour suppressors, p53 and Rb.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

BRCA1 interacts with components of the histone deacetylase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Nuclear localization and cell cycle-specific expression of CtIP, a protein that associates with the BRCA1 tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Regulation of Rad51 function by c-Abl in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Relationship of p215BRCA1 to tyrosine kinase signaling pathways and the cell cycle in normal and transformed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

BRCA1 physically associates with p53 and stimulates its transcriptional activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Ser727-dependent recruitment of MCM5 by Stat1alpha in IFN-gamma-induced transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

The retinoblastoma gene: a prototypic and multifunctional tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Lessons learned from BRCA1 and BRCA2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Sequence-specific transcriptional corepressor function for BRCA1 through a novel zinc finger protein, ZBRK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

The DNA damage response: putting checkpoints in perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

Transcriptional activation by BRCA1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

BRCA1 expression levels predict distant metastasis of sporadic breast cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

7 January 2021

The molecular and cellular biology of HER2/neu gene amplification/overexpression and the clinical development of herceptin (trastuzumab) therapy for breast cancer.

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

7 January 2021

The many interfaces of Mre11

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

7 January 2021

Signaling to p53: breaking the MDM2-p53 circuit

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

7 January 2021

RB regulates the stability and the apoptotic function of p53 via MDM2

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

7 January 2021

Myc requires distinct E2F activities to induce S phase and apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

7 January 2021

The DNA repair protein rad23 is a negative regulator of multi-ubiquitin chain assembly

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

7 January 2021

Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

7 January 2021

Cooperative tumorigenic effects of germline mutations in Rb and p53

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

7 January 2021

Methylation of the BRCA1 promoter region in sporadic breast and ovarian cancer: correlation with disease characteristics

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

7 January 2021

The cytokine hepatocyte growth factor/scatter factor inhibits apoptosis and enhances DNA repair by a common mechanism involving signaling through phosphatidyl inositol 3' kinase

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

7 January 2021

Immunolocalization of BRCA1 protein in normal breast tissue and sporadic invasive ductal carcinomas: a correlation with other biological parameters

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

7 January 2021

Activation of transcription in vitro by the BRCA1 carboxyl-terminal domain

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

7 January 2021

BRCA1 effects on the cell cycle and the DNA damage response are linked to altered gene expression

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

7 January 2021

Induction of the BRCA2 promoter by nuclear factor-kappa B

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

7 January 2021

The Mdm-2 amino terminus is required for Mdm2 binding and SUMO-1 conjugation by the E2 SUMO-1 conjugating enzyme Ubc9

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

7 January 2021

MyoD can induce cell cycle arrest but not muscle differentiation in the presence of dominant negative SWI/SNF chromatin remodeling enzymes

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

7 January 2021

Location of BRCA1 in human breast and ovarian cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

7 January 2021

Response: Location of BRCA1 in Human Breast and Ovarian Cancer Cells

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

7 January 2021

Ubiquitin-activating/conjugating activity of TAFII250, a mediator of activation of gene expression in Drosophila

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

7 January 2021

Hereditary breast cancer

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10178

7 January 2021