BRCA1 is phosphorylated at serine 1497 in vivo at a cyclin-dependent kinase 2 phosphorylation site (Q24554478)

2

W

Jiang

1 reference

29 November 2023

A G Craig

3

A G

Craig

1 reference

29 November 2023

T Hunter

4

T

Hunter

1 reference

29 November 2023

I M Verma

5

I M

Molecular and Cellular Biology

Verma

1 reference

29 November 2023

language of work or name

English

0 references

publication date

July 1999

0 references

published in

0 references

volume

19

0 references

page(s)

4843-54

0 references

issue

7

0 references

cites work

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BRCA1 proteins are transported to the nucleus in the absence of serum and splice variants BRCA1a, BRCA1b are tyrosine phosphoproteins that associate with E2F, cyclins and cyclin dependent kinases

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Localization of human BRCA1 and its loss in high-grade, non-inherited breast carcinomas

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BRCA1 required for transcription-coupled repair of oxidative DNA damage

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BRCA1 physically associates with p53 and stimulates its transcriptional activity.

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Cdc2-mediated phosphorylation of the gap junction protein, connexin43, during mitosis

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Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiP1.

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BRCA1 is a cell cycle-regulated nuclear phosphoprotein

27 September 2017

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Localization of BRCA1 and a splice variant identifies the nuclear localization signal

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The nuclear localization sequences of the BRCA1 protein interact with the importin-alpha subunit of the nuclear transport signal receptor

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Evidence for a transcriptional activation function of BRCA1 C-terminal region

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Inactivation of the mouse Brca1 gene leads to failure in the morphogenesis of the egg cylinder in early postimplantation development.

27 September 2017

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p53 in growth control and neoplasia

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Cell cycle regulation by the retinoblastoma family of growth inhibitory proteins

27 September 2017

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Cyclin dependent kinase regulation

27 September 2017

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Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities

27 September 2017

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Cyclins and cyclin-dependent kinases: take your partners

27 September 2017

1 reference

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27 September 2017

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Cyclin-dependent protein kinases: key regulators of the eukaryotic cell cycle

27 September 2017

1 reference

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The developmental pattern of Brca1 expression implies a role in differentiation of the breast and other tissues

27 September 2017

1 reference

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Driving the cell cycle: M phase kinase, its partners, and substrates

27 September 2017

1 reference

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Genetic analysis of breast cancer in the cancer and steroid hormone study

27 September 2017

1 reference

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Animal cell cycles and their control

27 September 2017

1 reference

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DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells

27 September 2017

1 reference

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Cell cycle regulation of BRCA1 messenger RNA in human breast epithelial cells

27 September 2017

1 reference

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Induction of apoptosis by the tumor suppressor protein BRCA1.

27 September 2017

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Aberrant subcellular localization of BRCA1 in breast cancer

27 September 2017

1 reference

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27 September 2017

1 reference

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Identification of a possible somatic BRCA1 mutation affecting translation efficiency in an early-onset sporadic breast cancer patient.

27 September 2017

1 reference

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Preferential allelic expression can lead to reduced expression of BRCA1 in sporadic breast cancers.

30 May 2018

1 reference

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Identification of a BRCA1-associated kinase with potential biological relevance.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84283

Relationship of p215BRCA1 to tyrosine kinase signaling pathways and the cell cycle in normal and transformed cells

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84283

Human, canine and murine BRCA1 genes: sequence comparison among species.

30 May 2018

1 reference

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BRCA1 protein products ... Functional motifs...

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84283

Loss of heterozygosity in human breast carcinomas in the ataxia telangiectasia, Cowden disease and BRCA1 gene regions

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84283

Mouse Brca1: localization sequence analysis and identification of evolutionarily conserved domains.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84283

BRCA1Mutations in a Population-Based Sample of Young Women with Breast Cancer

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84283

BRCA1 mutations in primary breast and ovarian carcinomas.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84283

Somatic mutations in the BRCA1 gene in sporadic ovarian tumours.

28 November 2018

1 reference

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Germ-line BRCA1 mutations in women with sporadic breast cancer: clinical correlations

28 November 2018

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Location of BRCA1 in human breast and ovarian cancer cells

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12 December 2020

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12 December 2020

Decreased BRCA1 expression levels may arrest the cell cycle through activation of p53 checkpoint in human sporadic breast tumors

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12 December 2020

Loss of heterozygosity in familial tumors from three BRCA1-linked kindreds

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12 December 2020

Identification of missense and truncating mutations in the BRCA1 gene in sporadic and familial breast and ovarian cancer

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12 December 2020

Genetic analysis of the BRCA1 region in a large breast/ovarian family: refinement of the minimal region containing BRCA1

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12 December 2020

Combined loss of BRCA1/BRCA2 in grade 3 breast carcinomas

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12 December 2020

Cellular substrates of p34cdc2 and its companion cyclin-dependent kinases

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12 December 2020

Response: Location of BRCA1 in Human Breast and Ovarian Cancer Cells

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12 December 2020

Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression

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12 December 2020

Osteopontin N-terminal domain contains a cryptic adhesive sequence recognized by alpha9beta1 integrin

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Crossref

https://api.crossref.org/works/10.1128%2FMCB.19.7.4843

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1128/MCB.19.7.4843

1 reference

release_cc2qmj5cbvfdpkf6vkucib6t7y

4564306

Fatcat ID

0 references

4564306

1 reference

1 reference

1 reference