Induction of the BRCA2 promoter by nuclear factor-kappa B (Q74232945)

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9 November 2019

title

Induction of the BRCA2 promoter by nuclear factor-kappa B (English)

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9 November 2019

5

Couch FJ

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9 November 2019

author name string

Wu K

1

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9 November 2019

Jiang SW

2

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9 November 2019

Thangaraju M

3

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9 November 2019

Wu G

4

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9 November 2019

language of work or name

English

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publication date

1 November 2000

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Journal of Biological Chemistry

9 November 2019

published in

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9 November 2019

volume

275

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9 November 2019

issue

45

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9 November 2019

page(s)

35548-35556

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Identification of the breast cancer susceptibility gene BRCA2

9 November 2019

cites work

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The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds

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Population-based study of risk of breast cancer in carriers of BRCA2 mutation

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Breast cancer genes--what are the real risks?

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RAB22 and RAB163/mouse BRCA2: proteins that specifically interact with the RAD51 protein

21 January 2018

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RAD51 interacts with the evolutionarily conserved BRC motifs in the human breast cancer susceptibility gene brca2

21 January 2018

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Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos

21 January 2018

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Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

21 January 2018

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Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation

21 January 2018

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Involvement of Brca2 in DNA repair

21 January 2018

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The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment

21 January 2018

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Isolation and initial characterization of the BRCA2 promoter

21 January 2018

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Developmental expression of Brca2 colocalizes with Brca1 and is associated with proliferation and differentiation in multiple tissues.

21 January 2018

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Mitotic checkpoint inactivation fosters transformation in cells lacking the breast cancer susceptibility gene, Brca2.

21 January 2018

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Patterns of loss of heterozygosity at loci from chromosome arm 13q suggests a possible involvement of BRCA2 in sporadic breast tumors

21 January 2018

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Prognostic value of loss of heterozygosity at BRCA2 in human breast carcinoma

21 January 2018

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Low incidence of BRCA2 mutations in breast carcinoma and other cancers

21 January 2018

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BRCA2 mutations in primary breast and ovarian cancers

21 January 2018

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Absence of methylation of CpG dinucleotides within the promoter of the breast cancer susceptibility gene BRCA2 in normal tissues and in breast and ovarian cancers

21 January 2018

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Overexpression of BRCA2 gene in sporadic breast tumours.

21 January 2018

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Generation of an integrated transcription map of the BRCA2 region on chromosome 13q12-q13

21 January 2018

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Loss of USF transcriptional activity in breast cancer cell lines.

21 January 2018

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Cell-type-dependent activity of the ubiquitous transcription factor USF in cellular proliferation and transcriptional activation

21 January 2018

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Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation

21 January 2018

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Transcriptional activation functions in BRCA2

21 January 2018

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The BRCA2 is a histone acetyltransferase

21 January 2018

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The BRCA2 gene product functionally interacts with p53 and RAD51

21 January 2018

1 reference

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A c-erbB-2 promoter-specific nuclear matrix protein from human breast tumor tissues mediates NF-kappaB DNA binding activity.

21 January 2018

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Aberrant nuclear factor-kappaB/Rel expression and the pathogenesis of breast cancer

21 January 2018

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The cellular transcription factor USF cooperates with varicella-zoster virus immediate-early protein 62 to symmetrically activate a bidirectional viral promoter

21 January 2018

1 reference

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Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region.

21 January 2018

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The helix-loop-helix containing transcription factor USF binds to and transactivates the promoter of the p53 tumor suppressor gene

21 January 2018

1 reference

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Transcription of the transforming growth factor-beta2 gene is dependent on an E-box located between an essential cAMP response element/activating transcription factor motif and the TATA box of the gene

21 January 2018

1 reference

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Upstream stimulatory factor regulates expression of the cell cycle-dependent cyclin B1 gene promoter

21 January 2018

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Functional domains of the transcription factor USF2: atypical nuclear localization signals and context-dependent transcriptional activation domains

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M004390200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10961992%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference