Involvement of Noxa in cellular apoptotic responses to interferon, double-stranded RNA, and virus infection (Q24294698)

Phorbol-12-myristate-13-acetate-induced protein 1

GOA release 2020-03-11

1 reference

positive regulation of extrinsic apoptotic signaling pathway via death domain receptors

GOA release 2020-03-11

1 reference

Journal of Biological Chemistry

GOA release 2020-03-11

author name string

Yaping Sun

series ordinal

1

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Douglas W Leaman

series ordinal

2

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language of work or name

English

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publication date

22 April 2005

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published in

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volume

280

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issue

16

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page(s)

15561-8

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cites work

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Apoptosis is promoted by the dsRNA-activated factor (DRAF1) during viral infection independent of the action of interferon or p53.

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Activation of the dsRNA-dependent protein kinase, PKR, induces apoptosis through FADD-mediated death signaling

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The 2-5A system in viral infection and apoptosis

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Identification of X-linked inhibitor of apoptosis-associated factor-1 as an interferon-stimulated gene that augments TRAIL Apo2L-induced apoptosis

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Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

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Analysis of the ultraviolet B response in primary human keratinocytes using oligonucleotide microarrays

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Integral role of Noxa in p53-mediated apoptotic response

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BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alpha

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The Molecular Mechanism of Noxa-induced Mitochondrial Dysfunction in p53-Mediated Cell Death

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BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

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BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

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Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays

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Novel growth and death related interferon-stimulated genes (ISGs) in melanoma: greater potency of IFN-beta compared with IFN-alpha2.

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Regulation of gene expression by pegylated IFN-alpha2b and IFN-alpha2b in human peripheral blood mononuclear cells

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Ectopic expression of toll-like receptor-3 (TLR-3) overcomes the double-stranded RNA (dsRNA) signaling defects of P2.1 cells

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Use of genetic suppressor elements to dissect distinct biological effects of separate p53 domains

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Transcriptional profiling of interferon regulatory factor 3 target genes: direct involvement in the regulation of interferon-stimulated genes

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The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction

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Adenoviral-mediated p53 transgene expression sensitizes both wild-type and null p53 prostate cancer cells in vitro to radiation

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IFNalpha sensitizes ME-180 human cervical cancer cells to TNFalpha-induced apoptosis by inhibiting cytoprotective NF-kappaB activation

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Interferon-gamma induces Ice gene expression and enhances cellular susceptibility to apoptosis in the U937 leukemia cell line

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IFN-alpha sensitizes human umbilical vein endothelial cells to apoptosis induced by double-stranded RNA.

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Apoptosis: an innate immune response to virus infection

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p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

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How cells respond to interferons

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Combinatorial association and abundance of components of interferon-stimulated gene factor 3 dictate the selectivity of interferon responses.

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Toll-like receptor 3: a link between toll-like receptor, interferon and viruses

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Interferon regulatory factor 3 and CREB-binding protein/p300 are subunits of double-stranded RNA-activated transcription factor DRAF1.

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Identification of the in vivo role of a viral bcl-2

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JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis

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Phosphorylation of the pro-apoptotic protein BIK: mapping of phosphorylation sites and effect on apoptosis

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Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

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BID: a novel BH3 domain-only death agonist

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Identification of novel isoforms of the BH3 domain protein Bim which directly activate Bax to trigger apoptosis

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Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

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Apo2L/TRAIL and Bcl-2-related proteins regulate type I interferon-induced apoptosis in multiple myeloma

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Tipping the balance between necrosis and apoptosis in human and murine cells treated with interferon and dsRNA.

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Downregulation of Bcl-2 sensitises interferon-resistant renal cancer cells to Fas.

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Interferon-alpha-induced apoptosis in U266 cells is associated with activation of the proapoptotic Bcl-2 family members Bak and Bax.

21 January 2018

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Viral Bcl-2 homologs and their role in virus replication and associated diseases

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p53 triggers apoptosis in oncogene-expressing fibroblasts by the induction of Noxa and mitochondrial Bax translocation

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7 January 2021

Transcriptional Induction by Double-stranded RNA Is Mediated by Interferon-stimulated Response Elements without Activation of Interferon-stimulated Gene Factor 3

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7 January 2021

A Specific Isozyme of 2′-5′ Oligoadenylate Synthetase Is a Dual Function Proapoptotic Protein of the Bcl-2 Family

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7 January 2021

Regulation of STAT-dependent pathways by growth factors and cytokines.

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7 January 2021

Molecular cloning and characterization of a cDNA for a novel phorbol-12-myristate-13-acetate-responsive gene that is highly expressed in an adult T-cell leukemia cell line

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7 January 2021