Genome of the human hookworm Necator americanus (Q22122067)

6 February 2023

29

Makedonka Mitreva

Makedonka

Mitreva

1 reference

6 February 2023

11

Patrick Minx

Patrick

Minx

1 reference

6 February 2023

6

John Martin

John

Martin

1 reference

6 February 2023

Rahul Tyagi

7

Rahul

Tyagi

1 reference

6 February 2023

Jason Mulvenna

19

Jason

Mulvenna

1 reference

6 February 2023

Javier Sotillo

20

Javier

Sotillo

1 reference

6 February 2023

John M Hawdon

26

John M

Hawdon

1 reference

6 February 2023

Shoba Ranganathan

21

Shoba

Ranganathan

1 reference

6 February 2023

Robin B Gasser

27

Robin B

Gasser

1 reference

6 February 2023

16

Paul W Sternberg

Paul W

Sternberg

1 reference

6 February 2023

13

Qi Wang

Qi

Wang

1 reference

6 February 2023

3

Bruce A Rosa

Bruce A

Rosa

1 reference

6 February 2023

12

Wesley C Warren

Wesley C

Warren

1 reference

6 February 2023

Élida Mara Leite Rabelo

Elida M Rabelo

22

Elida M

Rabelo

1 reference

16 August 2023

Yat T Tang

1

Yat T

Tang

1 reference

6 February 2023

Xin Gao

2

Xin

Gao

1 reference

6 February 2023

Sahar Abubucker

4

Sahar

Abubucker

1 reference

6 February 2023

Kymberlie Hallsworth-Pepin

5

Kymberlie

Hallsworth-Pepin

1 reference

6 February 2023

Esley Heizer

8

Esley

Heizer

1 reference

6 February 2023

Xu Zhang

9

Xu

Zhang

1 reference

6 February 2023

Veena Bhonagiri-Palsikar

10

Veena

Bhonagiri-Palsikar

1 reference

6 February 2023

Bin Zhan

14

Bin

Zhan

1 reference

6 February 2023

Annette Dougall

17

Annette

Dougall

1 reference

6 February 2023

Soraya Torres Gaze

18

Soraya Torres

Gaze

1 reference

6 February 2023

Richard K Wilson

23

Richard K

Wilson

1 reference

6 February 2023

Philip L Felgner

24

Philip L

Felgner

1 reference

6 February 2023

Jeffrey Bethony

25

Jeffrey

Bethony

1 reference

6 February 2023

Alex Loukas

28

Alex

Loukas

1 reference

Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported

6 February 2023

language of work or name

English

0 references

publication date

March 2014

0 references

published in

Nature Genetics

0 references

volume

46

0 references

page(s)

261-9

0 references

issue

3

0 references

copyright license

start time

19 January 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

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KEGG for representation and analysis of molecular networks involving diseases and drugs

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Fast and accurate short read alignment with Burrows-Wheeler transform

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Jalview Version 2--a multiple sequence alignment editor and analysis workbench

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JASPAR, the open access database of transcription factor-binding profiles: new content and tools in the 2008 update

19 March 2017

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RNAmmer: consistent and rapid annotation of ribosomal RNA genes

19 March 2017

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TRANSFAC and its module TRANSCompel: transcriptional gene regulation in eukaryotes

19 March 2017

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Genome sequencing in microfabricated high-density picolitre reactors

19 March 2017

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InterProScan: protein domains identifier

19 March 2017

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Gene finding in novel genomes

19 March 2017

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MUSCLE: multiple sequence alignment with high accuracy and high throughput

19 March 2017

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Rfam: an RNA family database

19 March 2017

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Gene ontology: tool for the unification of biology

19 March 2017

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tRNAscan-SE: a program for improved detection of transfer RNA genes in genomic sequence

19 March 2017

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Ascaris suum draft genome

19 March 2017

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Discovery of anthelmintic drug targets and drugs using chokepoints in nematode metabolic pathways

19 March 2017

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Using existing drugs as leads for broad spectrum anthelmintics targeting protein kinases

19 March 2017

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Principles of activation and permeation in an anion-selective Cys-loop receptor

19 March 2017

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edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

19 March 2017

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Clustal W and Clustal X version 2.0

19 March 2017

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OrthoMCL: Identification of Ortholog Groups for Eukaryotic Genomes

19 March 2017

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MrBayes 3: Bayesian phylogenetic inference under mixed models

19 March 2017

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T-Coffee: A novel method for fast and accurate multiple sequence alignment

19 March 2017

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Comparative protein modelling by satisfaction of spatial restraints

19 March 2017

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Classification and functional annotation of eukaryotic protein kinases

19 March 2017

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Efficacy of single-dose and triple-dose albendazole and mebendazole against soil-transmitted helminths and Taenia spp.: a randomized controlled trial

19 March 2017

1 reference

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Efficacy of current drugs against soil-transmitted helminth infections: systematic review and meta-analysis

19 March 2017

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How many drug targets are there?

19 March 2017

1 reference

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Interactive Tree Of Life (iTOL): an online tool for phylogenetic tree display and annotation

19 March 2017

1 reference

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Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

Feature-based prediction of non-classical and leaderless protein secretion

19 March 2017

1 reference

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Immune regulation by helminth parasites: cellular and molecular mechanisms

19 March 2017

1 reference

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The effect of the anthelmintic emodepside at the neuromuscular junction of the parasitic nematode Ascaris suum

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

Insights into SCP/TAPS proteins of liver flukes based on large-scale bioinformatic analyses of sequence datasets

19 March 2017

1 reference

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Effect of hookworm infection on wheat challenge in celiac disease--a randomised double-blinded placebo controlled trial

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

KEGG for integration and interpretation of large-scale molecular data sets

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

Accelerated Profile HMM Searches

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

Repbase Update, a database of eukaryotic repetitive elements

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

Comparative protein structure modeling using MODELLER

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

MAKER: an easy-to-use annotation pipeline designed for emerging model organism genomes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

KAAS: an automatic genome annotation and pathway reconstruction server

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

Annotation, submission and screening of repetitive elements in Repbase: RepbaseSubmitter and Censor

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

Drug repositioning: identifying and developing new uses for existing drugs

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

A combined transmembrane topology and signal peptide prediction method

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

Protein kinases--the major drug targets of the twenty-first century?

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

Overriding imatinib resistance with a novel ABL kinase inhibitor

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

10 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

The neuronal genome of Caenorhabditis elegans

28 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

Hookworm excretory/secretory products induce interleukin-4 (IL-4)+ IL-10+ CD4+ T cell responses and suppress pathology in a mouse model of colitis

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

The hookworm pharmacopoeia for inflammatory diseases

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

Helminth-host immunological interactions: prevention and control of immune-mediated diseases

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

Low efficacy of single-dose albendazole and mebendazole against hookworm and effect on concomitant helminth infection in Lao PDR.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

A history of hookworm vaccine development

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

SCP/TAPS proteins in helminths--where to from now?

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

Vaccinomics for the major blood feeding helminths of humans

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

Developing vaccines to combat hookworm infection and intestinal schistosomiasis

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

Serine/threonine phosphatases in socioeconomically important parasitic nematodes--prospects as novel drug targets?

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

Genetic and household determinants of predisposition to human hookworm infection in a Brazilian community

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

The immunology of human hookworm infections

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

Characterizing Ancylostoma caninum transcriptome and exploring nematode parasitic adaptation

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

QuickGO: a web-based tool for Gene Ontology searching

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

RNA Pol II accumulates at promoters of growth genes during developmental arrest.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

A portrait of the "SCP/TAPS" proteins of eukaryotes--developing a framework for fundamental research and biotechnological outcomes.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

Longer first introns are a general property of eukaryotic gene structure

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

Identification of the amino-acetonitrile derivative monepantel (AAD 1566) as a new anthelmintic drug development candidate

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

The putative chemoreceptor families of C. elegans

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

The nicotinic acetylcholine receptor gene family of the nematode Caenorhabditis elegans: an update on nomenclature

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

FUNC: a package for detecting significant associations between gene sets and ontological annotations

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

Human pancreatic digestive enzymes

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

Identification of humoral immune responses in protein microarrays using DNA microarray data analysis techniques

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

Expression of the Necator americanus hookworm larval antigen Na-ASP-2 in Pichia pastoris and purification of the recombinant protein for use in human clinical trials

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

Enzymes involved in the biogenesis of the nematode cuticle

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

Digestive proteases of blood-feeding nematodes.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

Ion channels and synaptic organization: analysis of the Drosophila genome

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

Molecular characterization of Ancylostoma ceylanicum Kunitz-type serine protease inhibitor: evidence for a role in hookworm-associated growth delay.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

Coexpression of neighboring genes in Caenorhabditis elegans is mostly due to operons and duplicate genes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

Vaccination Against the Canine Hookworm Diseases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

Computational analysis of Plasmodium falciparum metabolism: organizing genomic information to facilitate drug discovery

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

Proteolytic degradation of hemoglobin in the intestine of the human hookworm Necator americanus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

Ivermectin: A Potent New Antiparasitic Agent

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

Eotaxin is specifically cleaved by hookworm metalloproteases preventing its action in vitro and in vivo.

30 May 2018

1 reference

Acute Stroke Therapy by Inhibition of Neutrophils (ASTIN): an adaptive dose-response study of UK-279,276 in acute ischemic stroke.

21 January 2018

1 reference

TGF-beta and the evolution of nematode parasitism.

21 January 2018

1 reference

Target-based and whole-worm screening approaches to anthelmintic discovery.

21 January 2018

1 reference

In vitro studies on the relative sensitivity to ivermectin of Necator americanus and Ancylostoma ceylanicum.

21 January 2018

1 reference

Haemonchus contortus: ivermectin-induced paralysis of the pharynx.

21 January 2018

1 reference

Emerging Patterns of Hookworm Infection: Influence of Aging on the Intensity ofNecatorInfection in Hainan Province, People’s Republic of China

21 January 2018

1 reference

Necator americanus: maintenance through one hundred generations in golden hamsters (Mesocricetus auratus). I. Host sex-associated differences in hookworm burden and fecundity.

21 January 2018

1 reference

The evaluation of recombinant hookworm antigens as vaccines in hamsters (Mesocricetus auratus) challenged with human hookworm, Necator americanus

21 January 2018

1 reference

Using native and syntenically mapped cDNA alignments to improve de novo gene finding.

21 January 2018

1 reference

Proteomics analysis of the excretory/secretory component of the blood-feeding stage of the hookworm, Ancylostoma caninum

21 January 2018

1 reference

SIMPLE34: an improved and enhanced implementation for VAX and Sun computers of the SIMPLE algorithm for analysis of clustered repetitive motifs in nucleotide sequences.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978129

Levamisole in the treatment of ascariasis in children

29 November 2018

1 reference

12 December 2020

Secretion of metalloproteases by living infective larvae of Necator americanus

1 reference

12 December 2020

The use of human faeces for fertilizer is associated with increased intensity of hookworm infection in Vietnamese women

1 reference

12 December 2020

Effects of the novel anthelmintic emodepside on the locomotion, egg-laying behaviour and development of Caenorhabditis elegans

1 reference

12 December 2020

Identifiers

DOI

10.1038/NG.2875

1 reference

493123

0 references

493123

1 reference

1 reference

1 reference