Mood disorders in Huntington's disease: from behavior to cellular and molecular mechanisms (Q21131050)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24795586%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

title

Mood disorders in Huntington's disease: from behavior to cellular and molecular mechanisms (English)

1 reference

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17 March 2020

0 references

1 reference

1

Patrick Pla

Patrick

Pla

1 reference

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17 March 2020

3

Frédéric Saudou

Frédéric

Saudou

1 reference

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17 March 2020

4

Denis J David

Denis J

David

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17 March 2020

5

Sandrine Humbert

Sandrine

Humbert

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17 March 2020

Sophie Orvoen

2

Sophie

Orvoen

1 reference

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17 March 2020

language of work or name

English

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publication date

23 April 2014

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Frontiers in Behavioral Neuroscience

17 March 2020

published in

1 reference

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17 March 2020

volume

8

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17 March 2020

page(s)

135

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Congenital hydrocephalus associated with abnormal subcommissural organ in mice lacking huntingtin in Wnt1 cell lineages

17 March 2020

cites work

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Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons

19 March 2017

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14-3-3 protein interacts with Huntingtin-associated protein 1 and regulates its trafficking

19 March 2017

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Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior

19 March 2017

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

19 March 2017

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19 March 2017

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Cyclotraxin-B, the first highly potent and selective TrkB inhibitor, has anxiolytic properties in mice

12 September 2017

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Normal huntingtin function: an alternative approach to Huntington's disease

19 March 2017

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Inhibition of calpain cleavage of huntingtin reduces toxicity: accumulation of calpain/caspase fragments in the nucleus

19 March 2017

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Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes

19 March 2017

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Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

19 March 2017

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Interaction of huntingtin-associated protein with dynactin P150Glued

19 March 2017

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Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressants

19 March 2017

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Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes

19 March 2017

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Inactivation of the mouse Huntington's disease gene homolog Hdh

19 March 2017

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Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue

19 March 2017

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BDNF regulates Rab11-mediated recycling endosome dynamics to induce dendritic branching

19 March 2017

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Delivery of GABAARs to synapses is mediated by HAP1-KIF5 and disrupted by mutant huntingtin.

19 March 2017

1 reference

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Interaction of Huntingtin-associated protein-1 with kinesin light chain: implications in intracellular trafficking in neurons

19 March 2017

1 reference

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Essential role of brain-derived neurotrophic factor in adult hippocampal function

19 March 2017

1 reference

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Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules

19 March 2017

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Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice

19 March 2017

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Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions

19 March 2017

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Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress

7 April 2017

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Neurobiology of depression

7 April 2017

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Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

7 April 2017

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Rapid anxiolytic effects of a 5-HT₄ receptor agonist are mediated by a neurogenesis-independent mechanism

7 April 2017

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Cognitive dysfunction in unipolar depression: implications for treatment

12 September 2017

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GABAA receptor subtypes: Therapeutic potential in Down syndrome, affective disorders, schizophrenia, and autism

12 September 2017

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Choosing an animal model for the study of Huntington's disease

12 September 2017

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Huntingtin acts non cell-autonomously on hippocampal neurogenesis and controls anxiety-related behaviors in adult mouse

12 September 2017

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A Tale of Two Maladies? Pathogenesis of Depression with and without the Huntington's Disease Gene Mutation.

12 September 2017

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Characterization of depression in prodromal Huntington disease in the neurobiological predictors of HD (PREDICT-HD) study

12 September 2017

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BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities.

12 September 2017

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Mutant Huntingtin alters retrograde transport of TrkB receptors in striatal dendrites.

12 September 2017

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Genetic approaches for understanding the role of serotonin receptors in mood and behavior.

12 September 2017

1 reference

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Depression in the early stages of Huntington disease

12 September 2017

1 reference

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Depressive symptom severity is related to poorer cognitive performance in prodromal Huntington disease

12 September 2017

1 reference

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Environmental enrichment rescues female-specific hyperactivity of the hypothalamic-pituitary-adrenal axis in a model of Huntington's disease

12 September 2017

1 reference

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Brain-derived neurotrophic factor and neuropsychiatric disorders

12 September 2017

1 reference

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Patterns of serotonergic antidepressant usage in prodromal Huntington disease

12 September 2017

1 reference

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Major depressive disorder: new clinical, neurobiological, and treatment perspectives

12 September 2017

1 reference

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An evidence-based approach in the treatment of Huntington's disease.

12 September 2017

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Huntington's disease: clinical presentation and treatment

12 September 2017

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Cognitive impairment in Huntington disease: diagnosis and treatment

12 September 2017

1 reference

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Combined treatment with the mood stabilizers lithium and valproate produces multiple beneficial effects in transgenic mouse models of Huntington's disease

12 September 2017

1 reference

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Sexually dimorphic serotonergic dysfunction in a mouse model of Huntington's disease and depression

12 September 2017

1 reference

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Treatment of depressive-like behaviour in Huntington's disease mice by chronic sertraline and exercise.

12 September 2017

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The latent stem cell population is retained in the hippocampus of transgenic Huntington's disease mice but not wild-type mice

12 September 2017

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Neurogenesis and affective disorders

12 September 2017

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Phenotypic characterization of a genetically diverse panel of mice for behavioral despair and anxiety

12 September 2017

1 reference

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Depression in patients with Huntington disease correlates with alterations of the brain stem raphe depicted by transcranial sonography

12 September 2017

1 reference

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The role of BDNF in depression on the basis of its location in the neural circuitry

12 September 2017

1 reference

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BDNF overexpression in the forebrain rescues Huntington's disease phenotypes in YAC128 mice

12 September 2017

1 reference

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Tetrabenazine: the first approved drug for the treatment of chorea in US patients with Huntington disease.

12 September 2017

1 reference

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Deletion of running-induced hippocampal neurogenesis by irradiation prevents development of an anxious phenotype in mice

12 September 2017

1 reference

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Oppositional effects of serotonin receptors 5-HT1a, 2, and 2c in the regulation of adult hippocampal neurogenesis

12 September 2017

1 reference

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Molecular mechanisms and potential therapeutical targets in Huntington's disease

12 September 2017

1 reference

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Impaired TrkB-mediated ERK1/2 activation in huntington disease knock-in striatal cells involves reduced p52/p46 Shc expression

12 September 2017

1 reference

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Tetrabenazine is neuroprotective in Huntington's disease mice

12 September 2017

1 reference

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Strain differences in stress responsivity are associated with divergent amygdala gene expression and glutamate-mediated neuronal excitability

12 September 2017

1 reference

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Aberrant Rab11-dependent trafficking of the neuronal glutamate transporter EAAC1 causes oxidative stress and cell death in Huntington's disease

12 September 2017

1 reference

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Proteolysis of mutant huntingtin produces an exon 1 fragment that accumulates as an aggregated protein in neuronal nuclei in Huntington disease

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Inhibition of PI3K-Akt signaling blocks exercise-mediated enhancement of adult neurogenesis and synaptic plasticity in the dentate gyrus

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Wheel running and environmental enrichment differentially modify exon-specific BDNF expression in the hippocampus of wild-type and pre-motor symptomatic male and female Huntington's disease mice.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression.

12 September 2017

1 reference

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Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models

12 September 2017

1 reference

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Up-regulating BDNF with an ampakine rescues synaptic plasticity and memory in Huntington's disease knockin mice

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Deletion of TrkB in adult progenitors alters newborn neuron integration into hippocampal circuits and increases anxiety-like behavior

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Extensive early motor and non-motor behavioral deficits are followed by striatal neuronal loss in knock-in Huntington's disease mice

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment

12 September 2017

1 reference

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Acute hippocampal brain-derived neurotrophic factor restores motivational and forced swim performance after corticosterone

12 September 2017

1 reference

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Rodent genetic models of Huntington disease

12 September 2017

1 reference

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Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Sertraline slows disease progression and increases neurogenesis in N171-82Q mouse model of Huntington's disease

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

BDNF and the diseased nervous system: a delicate balance between adaptive and pathological processes of gene regulation.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Expression profiling of Huntington's disease models suggests that brain-derived neurotrophic factor depletion plays a major role in striatal degeneration

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Neuropsychiatry of Huntington's disease

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Psychiatric disorders in preclinical Huntington's disease

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Progressive alterations in the hypothalamic-pituitary-adrenal axis in the R6/2 transgenic mouse model of Huntington's disease

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Antidepressant action: to the nucleus and beyond

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Reduced hippocampal neurogenesis in R6/2 transgenic Huntington's disease mice

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Depressive disorders -- is it time to endorse different pathophysiologies?

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Testosterone suppression of CRH-stimulated cortisol in men.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

ERK1/2 activation is necessary for BDNF to increase dendritic spine density in hippocampal CA1 pyramidal neurons.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Role of neurotrophic factors in the etiology and treatment of mood disorders

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

The serum- and glucocorticoid-induced kinase SGK inhibits mutant huntingtin-induced toxicity by phosphorylating serine 421 of huntingtin.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Increased cell proliferation and neurogenesis in the adult human Huntington's disease brain

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Inhibition of tryptophan hydroxylase activity and decreased 5-HT1A receptor binding in a mouse model of Huntington's disease

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Altered fear circuits in 5-HT(1A) receptor KO mice

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Huntington disease in Maryland: clinical aspects of racial variation

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Biochemical aspects of Huntington's chorea

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Phosphorylation of mutant huntingtin at S421 restores anterograde and retrograde transport in neurons.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Physical activity fails to rescue hippocampal neurogenesis deficits in the R6/2 mouse model of Huntington's disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Psychological consequences and predictors of adverse events in the first 5 years after predictive testing for Huntington's disease.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

The influence of huntingtin protein size on nuclear localization and cellular toxicity.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

NMDA receptor losses in putamen from patients with Huntington's disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Up-regulation of the isoenzymes MAO-A and MAO-B in the human basal ganglia and pons in Huntington's disease revealed by quantitative enzyme radioautography.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

The antidepressant sertraline improves the phenotype, promotes neurogenesis and increases BDNF levels in the R6/2 Huntington's disease mouse model

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Reduced brain-derived neurotrophic factor is associated with a loss of serotonergic innervation in the hippocampus of aging mice.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Abnormalities of neurogenesis in the R6/2 mouse model of Huntington's disease are attributable to the in vivo microenvironment.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Regional- and age-dependent reduction in trkB receptor expression in the hippocampus is associated with altered spine morphologies.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Brain-derived neurotrophic factor and antidepressant drugs have different but coordinated effects on neuronal turnover, proliferation, and survival in the adult dentate gyrus.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

30 May 2018

Apathy is not depression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Anterograde transport of brain-derived neurotrophic factor and its role in the brain.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Reduced levels of 5-HT3 receptor recognition sites in the putamen of patients with Huntington's disease

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Seven cases of huntington's disease in childhood and levodopa induced improvement in the hypokinetic — Rigid form

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Serotonin-1 receptor binding sites in the human basal ganglia are decreased in Huntington's chorea but not in Parkinson's disease: a quantitative in vitro autoradiography study

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

The limbic-hypothalamic-pituitary-adrenal axis in Huntington's disease

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Differential distribution of exogenous BDNF, NGF, and NT-3 in the brain corresponds to the relative abundance and distribution of high-affinity and low-affinity neurotrophin receptors

30 May 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Anxiogenic-like effect of chronic corticosterone in the light-dark emergence task in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Increased hypothalamic-pituitary-adrenal axis activity in Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Psychiatric symptoms and CAG repeats in neurologically asymptomatic Huntington's disease gene carriers.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Adult neurogenesis is regulated by adrenal steroids in the dentate gyrus.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

5-HT1B receptor binding in degenerative movement disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Fluoxetine-induced exacerbation of chorea in Huntington's disease? A case report

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Rigidity in social and emotional memory in the R6/2 mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Psychiatric symptoms in Huntington's disease before diagnosis: the predict-HD study

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Striking changes in anxiety in Huntington's disease transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Reduced expression of the TrkB receptor in Huntington's disease mouse models and in human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Cognitive disorders and neurogenesis deficits in Huntington's disease mice are rescued by fluoxetine.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Early behavioral deficits in R6/2 mice suitable for use in preclinical drug testing

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Evaluation of antidepressant-related behavioral responses in mice lacking the serotonin transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

The IGF-1/Akt pathway is neuroprotective in Huntington's disease and involves Huntingtin phosphorylation by Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Sex differences in the regulation of serotonergic transmission and behavior in 5-HT receptor knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Dehydroepiandrosterone (DHEA) stimulates neurogenesis in the hippocampus of the rat, promotes survival of newly formed neurons and prevents corticosterone-induced suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Behavioural problems in Huntington's disease using the Problem Behaviours Assessment.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Behaviour changes in a transgenic model of Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Gender differences in treatment response to sertraline versus imipramine in chronic depression

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Decreased hippocampal cell proliferation in R6/1 Huntington's mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Neurogenesis in the R6/1 transgenic mouse model of Huntington's disease: effects of environmental enrichment

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Serum dehydroepiandrosterone and cortisol measurements in Huntington's chorea

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Altered depression-related behaviors and functional changes in the dorsal raphe nucleus of serotonin transporter-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Serotonergic cells of the rat raphe nuclei express mRNA of tyrosine kinase B (trkB), the high-affinity receptor for brain derived neurotrophic factor (BDNF).

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Specific psychiatric manifestations among preclinical Huntington disease mutation carriers

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Corticostriatal synaptic function in mouse models of Huntington's disease: early effects of huntingtin repeat length and protein load

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Brain-derived neurotrophic factor conditional knockouts show gender differences in depression-related behaviors.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Chronic low dose corticosterone exposure decreased hippocampal cell proliferation, volume and induced anxiety and depression like behaviours in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Molecular and behavioral analysis of the R6/1 Huntington's disease transgenic mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Gene-environment interactions modulating cognitive function and molecular correlates of synaptic plasticity in Huntington's disease transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Huntington's disease knock-in male mice show specific anxiety-like behaviour and altered neuronal maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Differential effects of voluntary physical exercise on behavioral and brain-derived neurotrophic factor expression deficits in Huntington's disease transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Altered serotonin receptor expression is associated with depression-related behavior in the R6/1 transgenic mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Executive dysfunction in early stages of Huntington's disease is associated with striatal and insular atrophy: a neuropsychological and voxel-based morphometric study.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Brain-derived neurotrophic factor modulates dopaminergic deficits in a transgenic mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Prevention of depressive behaviour in the YAC128 mouse model of Huntington disease by mutation at residue 586 of huntingtin

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Marked differences in neurochemistry and aggregates despite similar behavioural and neuropathological features of Huntington disease in the full-length BACHD and YAC128 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Pharmacologically diverse antidepressants rapidly activate brain-derived neurotrophic factor receptor TrkB and induce phospholipase-Cgamma signaling pathways in mouse brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Psychiatric disorders in Huntington's disease: a 2-year follow-up study

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Depression and Stages of Huntington's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNBEH.2014.00135

Cortisol and depression in pre-diagnosed and early stage Huntington's disease

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Huntingtin mediates anxiety/depression-related behaviors and hippocampal neurogenesis.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Ventral hippocampal molecular pathways and impaired neurogenesis associated with 5-HT₁A and 5-HT₁B receptors disruption in mice.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Longitudinal evaluation of neuropsychiatric symptoms in Huntington's disease

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Disrupted GABAAR trafficking and synaptic inhibition in a mouse model of Huntington's disease

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Altered adult hippocampal neurogenesis in the YAC128 transgenic mouse model of Huntington disease

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Hypothalamic-pituitary-adrenal axis functioning in Huntington's disease mutation carriers compared with mutation-negative first-degree controls

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Cross-sectional study on prevalences of psychiatric disorders in mutation carriers of Huntington's disease compared with mutation-negative first-degree relatives

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Systematic assessment of BDNF and its receptor levels in human cortices affected by Huntington's disease

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

TrkB but not trkC receptors are necessary for postnatal maintenance of hippocampal spines.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Oral uridine pro-drug PN401 is neuroprotective in the R6/2 and N171-82Q mouse models of Huntington's disease

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Depression and stages of Huntington's disease.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Progressive loss of BDNF in a mouse model of Huntington's disease and rescue by BDNF delivery

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Generalized brain and skin proteasome inhibition in Huntington's disease

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Miniature synaptic transmission and BDNF modulate dendritic spine growth and form in rat CA1 neurones

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Activation of the TrkB neurotrophin receptor is induced by antidepressant drugs and is required for antidepressant-induced behavioral effects.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Behavioral changes in Huntington Disease

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Antidepressant-like behavioral effects in 5-hydroxytryptamine(1A) and 5-hydroxytryptamine(1B) receptor mutant mice.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Remotivation therapy and Huntington's disease

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Serotonergic modulation of neurotransmission in the rat basolateral amygdala.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Characterization of [3H]GR 113808 binding to 5-HT4 receptors in brain tissues from patients with neurodegenerative disorders

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005937

Neurotrophins and synaptic plasticity

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24795586

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Serotonergic mediation of the effects of fluoxetine, but not desipramine, in the rat forced swimming test

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24795586

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3389/FNBEH.2014.00135

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24795586%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24795586%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24795586%20AND%20SRC:MED&resulttype=core&format=json