Activation of the TrkB neurotrophin receptor is induced by antidepressant drugs and is required for antidepressant-induced behavioral effects. (Q44270223)

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English	Activation of the TrkB neurotrophin receptor is induced by antidepressant drugs and is required for antidepressant-induced behavioral effects.	scientific article

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16 December 2019

Activation of the TrkB neurotrophin receptor is induced by antidepressant drugs and is required for antidepressant-induced behavioral effects (English)

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16 December 2019

Annakaisa Haapasalo

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16 December 2019

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Tommi Saarelainen

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16 December 2019

Panu Hendolin

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Guilherme Lucas

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16 December 2019

Eija Koponen

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16 December 2019

Ewen MacDonald

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16 December 2019

Karin Agerman

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16 December 2019

Hiroyuki Nawa

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16 December 2019

Raquel Aloyz

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1 January 2003

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16 December 2019

Journal of Neuroscience

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16 December 2019

349-357

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16 December 2019

1

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16 December 2019

Neurotrophins and depression

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of noradrenergic neuronal firing by selective serotonin reuptake blockers

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophins and synaptic plasticity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Morphometric evidence for neuronal and glial prefrontal cell pathology in major depression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antidepressants for the new millennium

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

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Memantine is a clinically well tolerated N-methyl-D-aspartate (NMDA) receptor antagonist--a review of preclinical data

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activity-dependent activation of TrkB neurotrophin receptors in the adult CNS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

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Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BDNF promotes the regenerative sprouting, but not survival, of injured serotonergic axons in the adult rat brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

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Cortical degeneration in the absence of neurotrophin signaling: dendritic retraction and neuronal loss after removal of the receptor TrkB.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cAMP response element-mediated gene transcription is upregulated by chronic antidepressant treatment.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequential activation of the 5-HT1(A) serotonin receptor and TrkB induces the serotonergic neuronal phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophin signal transduction in the nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transgenic Mice Overexpressing Truncated trkB Neurotrophin Receptors in Neurons Show Increased Susceptibility to Cortical Injury after Focal Cerebral Ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transgenic mice overexpressing truncated trkB neurotrophin receptors in neurons have impaired long-term spatial memory but normal hippocampal LTP.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activity-dependent release of endogenous brain-derived neurotrophic factor from primary sensory neurons detected by ELISA in situ

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physical activity and antidepressant treatment potentiate the expression of specific brain-derived neurotrophic factor transcripts in the rat hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

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Truncated trkB.T1 is dominant negative inhibitor of trkB.TK+-mediated cell survival.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of Trk neurotrophin receptors in the absence of neurotrophins

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

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Neurotrophins as synaptic modulators

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

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How antidepressants work: new perspectives on the pathophysiology of depressive disorder

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cellular neurobiology of depression

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophins: roles in neuronal development and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Performance of heterozygous brain-derived neurotrophic factor knockout mice on behavioral analogues of anxiety, nociception, and depression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

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The neuroprotective agent memantine induces brain-derived neurotrophic factor and trkB receptor expression in rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

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Fluoxetine modulates motor performance and cerebral activation of patients recovering from stroke

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurobiology of depression

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessing antidepressant activity in rodents: recent developments and future needs

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of sleep deprivation on brain metabolism of depressed patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of serotonin reuptake

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral despair in mice: a primary screening test for antidepressants

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antinociceptive effect of brain-derived neurotrophic factor and neurotrophin-3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of neurotrophin-3 leads to deficiencies in the peripheral nervous system and loss of limb proprioceptive afferents

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BDNF protein measured by a novel enzyme immunoassay in normal brain and after seizure: partial disagreement with mRNA levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stress and glucocorticoids affect the expression of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional cerebral blood flow in mood disorders, III. Treatment and clinical response

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice lacking brain-derived neurotrophic factor develop with sensory deficits

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptic activity and the construction of cortical circuits

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

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BDNF increases monoaminergic activity in rat brain following intracerebroventricular or intraparenchymal administration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antidepressant-like effect of brain-derived neurotrophic factor (BDNF).

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subgenual prefrontal cortex abnormalities in mood disorders.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A molecular and cellular theory of depression

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional neuroimaging studies of depression: the anatomy of melancholia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Point mutation in trkB causes loss of NT4-dependent neurons without major effects on diverse BDNF responses.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular and cellular actions of chronic electroconvulsive seizures.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophin trafficking by anterograde transport.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monoamine dysfunction and the pathophysiology and treatment of depression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12514234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.23-01-00349.2003

1 reference

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16 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12514234%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12514234%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

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