Hsp70 and Hsp40 inhibit an inter-domain interaction necessary for transcriptional activity in the androgen receptor (Q92509338)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31395886%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

title

Hsp70 and Hsp40 inhibit an inter-domain interaction necessary for transcriptional activity in the androgen receptor (English)

1 reference

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Author Correction: Hsp70 and Hsp40 inhibit an inter-domain interaction necessary for transcriptional activity in the androgen receptor

30 April 2020

corrigendum / erratum

0 references

author

Jennifer N Rauch

5

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30 April 2020

Daniel M C Schwarz

7

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30 April 2020

Elisa Giorgetti

11

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30 April 2020

Roberta Pierattelli

13

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30 April 2020

Isabella C Felli

14

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30 April 2020

Jesús García

16

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30 April 2020

Jason E Gestwicki

18

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30 April 2020

Xavier Salvatella

20

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30 April 2020

author name string

Bahareh Eftekharzadeh

1

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30 April 2020

Varuna C Banduseela

2

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30 April 2020

Giulio Chiesa

3

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30 April 2020

Paula Martínez-Cristóbal

4

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30 April 2020

Samir R Nath

6

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30 April 2020

Hao Shao

8

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30 April 2020

Marta Marin-Argany

9

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30 April 2020

Claudio Di Sanza

10

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30 April 2020

Zhigang Yu

12

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30 April 2020

Isabelle Brun-Heath

15

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30 April 2020

Ángel R Nebreda

17

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30 April 2020

Andrew P Lieberman

19

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30 April 2020

publication date

8 August 2019

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30 April 2020

published in

Nature Communications

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30 April 2020

volume

10

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30 April 2020

issue

1

1 reference

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30 April 2020

page(s)

3562

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Side chain to main chain hydrogen bonds stabilize a polyglutamine helix in a transcription factor

30 April 2020

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1 reference

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Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer

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Hsp70 binds to the androgen receptor N-terminal domain and modulates the receptor function in prostate cancer cells

11 February 2021

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Polyglutamine Repeats in Neurodegenerative Diseases

11 February 2021

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Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer

11 February 2021

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Exploration of Benzothiazole Rhodacyanines as Allosteric Inhibitors of Protein-Protein Interactions with Heat Shock Protein 70 (Hsp70)

11 February 2021

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The disorderly conduct of Hsc70 and its interaction with the Alzheimer's-related Tau protein

11 February 2021

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Targeting the Hsp40/Hsp70 Chaperone Axis as a Novel Strategy to Treat Castration-Resistant Prostate Cancer

11 February 2021

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Spinal and bulbar muscular atrophy

11 February 2021

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X-Linked Inhibitor of Apoptosis Protein (XIAP) is a Client of Heat Shock Protein 70 (Hsp70) and a Biomarker of its Inhibition

11 February 2021

1 reference

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Regulation of Androgen Receptor Activity by Transient Interactions of Its Transactivation Domain with General Transcription Regulators.

11 February 2021

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The Plasticity of the Hsp90 Co-chaperone System.

11 February 2021

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Development of Bag-1L as a therapeutic target in androgen receptor-dependent prostate cancer

11 February 2021

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Stabilizing the Hsp70-Tau Complex Promotes Turnover in Models of Tauopathy

11 February 2021

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EPI-001, A Compound Active against Castration-Resistant Prostate Cancer, Targets Transactivation Unit 5 of the Androgen Receptor

11 February 2021

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Sequence Context Influences the Structure and Aggregation Behavior of a PolyQ Tract

11 February 2021

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Preventing the Androgen Receptor N/C Interaction Delays Disease Onset in a Mouse Model of SBMA

11 February 2021

1 reference

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How hsp70 molecular machines interact with their substrates to mediate diverse physiological functions

11 February 2021

1 reference

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Targeting heat shock proteins in metastatic castration-resistant prostate cancer

11 February 2021

1 reference

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Molecular interaction between the chaperone Hsc70 and the N-terminal flank of huntingtin exon 1 modulates aggregation

11 February 2021

1 reference

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Modulation of the maladaptive stress response to manage diseases of protein folding

11 February 2021

1 reference

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Targeting Hsp90/Hsp70-based protein quality control for treatment of adult onset neurodegenerative diseases

11 February 2021

1 reference

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A model in which heat shock protein 90 targets protein-folding clefts: rationale for a new approach to neuroprotective treatment of protein folding diseases

11 February 2021

1 reference

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Glucocorticoid receptor function regulated by coordinated action of the Hsp90 and Hsp70 chaperone cycles

11 February 2021

1 reference

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Hsp70 chaperones are non-equilibrium machines that achieve ultra-affinity by energy consumption

11 February 2021

1 reference

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Hsp90-Tau complex reveals molecular basis for specificity in chaperone action

11 February 2021

1 reference

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Chaperone machines for protein folding, unfolding and disaggregation

11 February 2021

1 reference

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Molecular chaperone functions in protein folding and proteostasis

11 February 2021

1 reference

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Mini-review: Foldosome regulation of androgen receptor action in prostate cancer

11 February 2021

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Activation of Hsp70 reduces neurotoxicity by promoting polyglutamine protein degradation

11 February 2021

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Molecular chaperones DnaK and DnaJ share predicted binding sites on most proteins in the E. coli proteome.

11 February 2021

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Physical chemistry of polyglutamine: intriguing tales of a monotonous sequence

11 February 2021

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Slow amyloid nucleation via α-helix-rich oligomeric intermediates in short polyglutamine-containing huntingtin fragments.

11 February 2021

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Allosteric drugs: the interaction of antitumor compound MKT-077 with human Hsp70 chaperones

11 February 2021

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Kinetics of amyloid beta monomer-to-oligomer exchange by NMR relaxation.

11 February 2021

1 reference

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The chaperonin TRiC blocks a huntingtin sequence element that promotes the conformational switch to aggregation

11 February 2021

1 reference

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Structural characterization of the native NH2-terminal transactivation domain of the human androgen receptor: a collapsed disordered conformation underlies structural plasticity and protein-induced folding

11 February 2021

1 reference

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Sensitive biochemical aggregate detection reveals aggregation onset before symptom development in cellular and murine models of Huntington's disease

11 February 2021

1 reference

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Direct observation of individual endogenous protein complexes in situ by proximity ligation

11 February 2021

1 reference

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Androgen-dependent pathology demonstrates myopathic contribution to the Kennedy disease phenotype in a mouse knock-in model

11 February 2021

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Abnormalities of germ cell maturation and sertoli cell cytoskeleton in androgen receptor 113 CAG knock-in mice reveal toxic effects of the mutant protein

11 February 2021

1 reference

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Molecular chaperones throughout the life cycle of the androgen receptor

11 February 2021

1 reference

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The CCPN data model for NMR spectroscopy: development of a software pipeline

11 February 2021

1 reference

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Hsp70 chaperones: cellular functions and molecular mechanism

11 February 2021

1 reference

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Structural basis for androgen receptor interdomain and coactivator interactions suggests a transition in nuclear receptor activation function dominance

11 February 2021

1 reference

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Unfolded proteins and protein folding studied by NMR.

11 February 2021

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Castration restores function and neurofilament alterations of aged symptomatic males in a transgenic mouse model of spinal and bulbar muscular atrophy.

11 February 2021

1 reference

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An androgen receptor NH2-terminal conserved motif interacts with the COOH terminus of the Hsp70-interacting protein (CHIP)

11 February 2021

1 reference

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Androgen receptor in prostate cancer

11 February 2021

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Structural basis of androgen receptor binding to selective androgen response elements.

11 February 2021

1 reference

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Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery

11 February 2021

1 reference

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Ligand promotes intranuclear inclusions in a novel cell model of spinal and bulbar muscular atrophy

11 February 2021

1 reference

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Androgen-dependent neurodegeneration by polyglutamine-expanded human androgen receptor in Drosophila.

11 February 2021

1 reference

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Testosterone reduction prevents phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy

11 February 2021

1 reference

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Molecular biology of the androgen receptor

11 February 2021

1 reference

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Protein-protein interactions probed by nuclear magnetic resonance spectroscopy

11 February 2021

1 reference

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Its substrate specificity characterizes the DnaJ co-chaperone as a scanning factor for the DnaK chaperone.

11 February 2021

1 reference

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Sequence complexity of disordered protein

11 February 2021

1 reference

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Structural evidence for ligand specificity in the binding domain of the human androgen receptor. Implications for pathogenic gene mutations

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6687723

FXXLF and WXXLF sequences mediate the NH2-terminal interaction with the ligand binding domain of the androgen receptor

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6687723

Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone

11 February 2021

1 reference

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Nuclear inclusions of the androgen receptor protein in spinal and bulbar muscular atrophy

11 February 2021

1 reference

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Steroid receptor interactions with heat shock protein and immunophilin chaperones

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6687723

Substrate specificity of the DnaK chaperone determined by screening cellulose-bound peptide libraries

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6687723

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6687723

Kinetics of molecular chaperone action

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6687723

Hold 'em and fold 'em: chaperones and signal transduction

11 February 2021

1 reference

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Hydrophobicity of amino acid residues in globular proteins.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6687723

Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6687723

10.1038/S41467-019-11594-Y

11 February 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31395886%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31395886%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

1 reference