Cooperative interactions of PTEN deficiency and RAS activation in melanoma metastasis (Q84392766)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21686270%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

review article

1 reference

title

Cooperative interactions of PTEN deficiency and RAS activation in melanoma metastasis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21686270%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

author name string

Minjung Kim

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21686270%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

publication date

1 November 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21686270%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

published in

Small GTPases (journal)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21686270%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

volume

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21686270%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21686270%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

page(s)

161-164

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21686270%20AND%20SRC:MED&resulttype=core&format=json

Examination of mutations in BRAF, NRAS, and PTEN in primary cutaneous melanoma.

5 February 2020

cites work

1 reference

12 December 2020

Akt1 ablation inhibits, whereas Akt2 ablation accelerates, the development of mammary adenocarcinomas in mouse mammary tumor virus (MMTV)-ErbB2/neu and MMTV-polyoma middle T transgenic mice

1 reference

12 December 2020

Signal transduction from multiple Ras effectors

1 reference

12 December 2020

The PTEN-AKT3 signaling cascade as a therapeutic target in melanoma

1 reference

12 December 2020

Genetic alterations in signaling pathways in melanoma

1 reference

12 December 2020

Both products of the mouse Ink4a/Arf locus suppress melanoma formation in vivo.

1 reference

12 December 2020

A novel AKT3 mutation in melanoma tumours and cell lines

1 reference

12 December 2020

Cooperative interactions of PTEN deficiency and RAS activation in melanoma metastasis

1 reference

12 December 2020

Mutation and allelic loss of the PTEN/MMAC1 gene in primary and metastatic melanoma biopsies

1 reference

12 December 2020

PTEN loss promotes rasHa-mediated papillomatogenesis via dual up-regulation of AKT activity and cell cycle deregulation but malignant conversion proceeds via PTEN-associated pathways

1 reference

12 December 2020

Binding of ras to phosphoinositide 3-kinase p110alpha is required for ras-driven tumorigenesis in mice

1 reference

12 December 2020

Mutations of the BRAF gene in human cancer

1 reference

12 December 2020

The Catalogue of Somatic Mutations in Cancer (COSMIC)

1 reference

12 December 2020

A mouse model of melanoma driven by oncogenic KRAS.

1 reference

12 December 2020

Essential role for oncogenic Ras in tumour maintenance

1 reference

12 December 2020

Disruption of the MMAC1/PTEN gene by deletion or mutation is a frequent event in malignant melanoma.

1 reference

12 December 2020

Relative reciprocity of NRAS and PTEN/MMAC1 alterations in cutaneous melanoma cell lines.

1 reference

12 December 2020

High frequency of BRAF mutations in nevi

1 reference

12 December 2020

Somatic p16(INK4a) loss accelerates melanomagenesis

1 reference

12 December 2020

PTEN loss accelerates KrasG12D-induced pancreatic cancer development

1 reference

12 December 2020

Deregulated Akt3 activity promotes development of malignant melanoma

1 reference

12 December 2020

Genetic interaction between NRAS and BRAF mutations and PTEN/MMAC1 inactivation in melanoma

1 reference

12 December 2020

Braf(V600E) cooperates with Pten loss to induce metastatic melanoma

1 reference

12 December 2020

Compartmentalization of Ras proteins

1 reference

12 December 2020

Dual inactivation of RB and p53 pathways in RAS-induced melanomas

1 reference

12 December 2020

Differential oncogenic potential of activated RAS isoforms in melanocytes

1 reference

12 December 2020

Metastasizing Melanoma Formation Caused by Expression of Activated N-RasQ61Kon an INK4a-Deficient Background

1 reference

12 December 2020

Melanoma genetics and the development of rational therapeutics

1 reference

12 December 2020

Malignant melanoma: genetics and therapeutics in the genomic era.

1 reference

12 December 2020

E-cadherin, beta-catenin, and ZEB1 in malignant progression of cancer

1 reference

12 December 2020

Pten inactivation accelerates oncogenic K-ras-initiated tumorigenesis in a mouse model of lung cancer

1 reference

12 December 2020

PTEN signaling pathways in melanoma

1 reference

12 December 2020

Classifying Melanocytic Tumors Based on DNA Copy Number Changes

1 reference

12 December 2020

Melanocytic nevus-like hyperplasia and melanoma in transgenic BRAFV600E mice

1 reference

12 December 2020

Genetic analysis of Pten and Ink4a/Arf interactions in the suppression of tumorigenesis in mice

1 reference

12 December 2020

Modeling genomic diversity and tumor dependency in malignant melanoma

1 reference

12 December 2020

Oncogenic Braf induces melanocyte senescence and melanoma in mice

1 reference

12 December 2020

Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase

1 reference

12 December 2020

Overexpression of AKT2/protein kinase Bbeta leads to up-regulation of beta1 integrins, increased invasion, and metastasis of human breast and ovarian cancer cells

1 reference

12 December 2020

Cooperative effects of INK4a and ras in melanoma susceptibility in vivo

1 reference

12 December 2020

Role of epidermal growth factor receptor signaling in RAS-driven melanoma

1 reference

12 December 2020

AKT2 is a downstream target of metabotropic glutamate receptor 1 (Grm1).

1 reference

12 December 2020

1 reference

12 December 2020

MicroRNAs differentially regulated by Akt isoforms control EMT and stem cell renewal in cancer cells.

1 reference

12 December 2020

Identifiers

DOI

10.4161/SGTP.1.3.14344

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21686270%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21686270%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference