A mouse model of melanoma driven by oncogenic KRAS. (Q41967375)

14 October 2017

A mouse model of melanoma driven by oncogenic KRAS. (English)

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14 October 2017

2

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14 October 2017

7

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14 October 2017

6

Jorge S Reis-Filho

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14 October 2017

3

Felipe C Geyer

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14 October 2017

5

Maryou Lambros

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14 October 2017

Carla Milagre

1

1 reference

PMCID

2896549

14 October 2017

Robert Hayward

series ordinal

4

1 reference

PMCID

2896549

14 October 2017

language of work or name

English

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publication date

1 June 2010

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14 October 2017

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14 October 2017

70

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14 October 2017

13

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14 October 2017

5549-5557

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Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF

14 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896549

Epidemiology, staging (new system), and prognosis of cutaneous melanoma

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896549

An integrative genomic and transcriptomic analysis reveals molecular pathways and networks regulated by copy number aberrations in basal-like, HER2 and luminal cancers

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896549

Ras signaling and therapies

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896549

Oncogenic Braf induces melanocyte senescence and melanoma in mice

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896549

Tiling path genomic profiling of grade 3 invasive ductal breast cancers

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896549

Immunohistochemical characteristics of melanoma

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896549

Differential oncogenic potential of activated RAS isoforms in melanocytes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896549

Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896549

Targeting RAS signalling pathways in cancer therapy

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896549

Dual inactivation of RB and p53 pathways in RAS-induced melanomas

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896549

Essential role for oncogenic Ras in tumour maintenance

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896549

Inhibition of the mitogen-activated protein kinase pathway triggers B16 melanoma cell differentiation.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896549

Cooperative effects of INK4a and ras in melanoma susceptibility in vivo

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896549

K-ras is an essential gene in the mouse with partial functional overlap with N-ras

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896549

ras oncogenes in human cancer: a review

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896549

Spatiotemporal gene control by the Cre-ERT2 system in melanocytes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896549

Pigmented epithelioid melanocytoma: a low-grade melanocytic tumor with metastatic potential indistinguishable from animal-type melanoma and epithelioid blue nevus

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896549

Mouse model for lung tumorigenesis through Cre/lox controlled sporadic activation of the K-Ras oncogene

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896549

Hyperpigmentation and melanocytic hyperplasia in transgenic mice expressing the human T24 Ha-ras gene regulated by a mouse tyrosinase promoter.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896549

EGFR amplification and lack of activating mutations in metaplastic breast carcinomas

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896549

Metastasizing Melanoma Formation Caused by Expression of Activated N-RasQ61Kon an INK4a-Deficient Background

2 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896549

K-ras is essential for the development of the mouse embryo

2 December 2018

1 reference

12 December 2020

Neonatal ultraviolet radiation exposure is critical for malignant melanoma induction in pigmented Tpras transgenic mice

1 reference

12 December 2020

An Inducible Mouse Model of Melanoma Expressing a Defined Tumor Antigen

1 reference

12 December 2020

Compartmentalization of Ras proteins

1 reference

12 December 2020

10.1158/0008-5472.CAN-09-4254

Identifiers

DOI

1 reference

14 October 2017

1 reference

14 October 2017

1 reference

PMCID

2896549