Bone morphogenetic protein 4 (Q700001)

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mammalian protein found in Homo sapiens
  • bone morphogenetic protein 2B
  • BMP-2B
  • bone morphogenetic protein 4
  • BMP4
edit
Language Label Description Also known as
English
Bone morphogenetic protein 4
mammalian protein found in Homo sapiens
  • bone morphogenetic protein 2B
  • BMP-2B
  • bone morphogenetic protein 4
  • BMP4

Statements

molecular function
heparin binding
determination method
IEA
1 reference
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
cytokine activity
determination method
IDA
IEA
2 references
retrieved
18 July 2017
stated in
UniProt-GOA
curator
UniProt
UniProt ID
P12644
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
retrieved
18 July 2017
stated in
Endogenous TGF-beta signaling suppresses maturation of osteoblastic mesenchymal cells.
UniProt-GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IDA
co-receptor binding
determination method
IPI
1 reference
retrieved
18 July 2017
stated in
Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression
UniProt-GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IPI
transforming growth factor beta receptor binding
determination method
IBA
1 reference
retrieved
18 July 2017
stated in
UniProt-GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IBA
growth factor activity
determination method
IEA
2 references
retrieved
18 July 2017
stated in
UniProt-GOA
curator
UniProt
UniProt ID
P12644
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
retrieved
18 July 2017
stated in
UniProt-GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
BMP receptor binding
determination method
IDA
1 reference
retrieved
18 July 2017
stated in
A mammalian serine/threonine kinase receptor specifically binds BMP-2 and BMP-4
UniProt-GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IDA
protein binding
determination method
IPI
7 references
retrieved
18 July 2017
stated in
The daf-4 gene encodes a bone morphogenetic protein receptor controlling C. elegans dauer larva development
UniProt-GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IPI
retrieved
18 July 2017
stated in
Agrin binds BMP2, BMP4 and TGFbeta1
UniProt-GOA
curator
UniProt
UniProt ID
P12644
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IPI
retrieved
18 July 2017
stated in
Targeting of bone morphogenetic protein growth factor complexes to fibrillin
UniProt-GOA
curator
UniProt
UniProt ID
P12644
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IPI
retrieved
18 July 2017
stated in
DIP2 disco-interacting protein 2 homolog A (Drosophila) is a candidate receptor for follistatin-related protein/follistatin-like 1--analysis of their binding with TGF-β superfamily proteins
UniProt-GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IPI
retrieved
18 July 2017
stated in
WFIKKN1 and WFIKKN2 bind growth factors TGFβ1, BMP2 and BMP4 but do not inhibit their signalling activity
UniProt-GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IPI
retrieved
18 July 2017
stated in
Functional analysis of bone morphogenetic protein type II receptor mutations underlying primary pulmonary hypertension
UniProt-GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IPI
retrieved
18 July 2017
stated in
The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4
UniProt-GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IPI
chemoattractant activity
determination method
IDA
1 reference
retrieved
18 July 2017
stated in
Evidence that bone morphogenetic protein 4 has multiple biological functions during kidney and urinary tract development
UniProt-GOA
curator
UniProt
UniProt ID
P12644
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IDA
cell component
extracellular region
determination method
ISS
TAS
IEA
4 references
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
TAS
retrieved
18 July 2017
stated in
UniProt-GOA
curator
UniProt
UniProt ID
P12644
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
ISS
retrieved
18 July 2017
stated in
UniProt-GOA
curator
UniProt
UniProt ID
P12644
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
proteinaceous extracellular matrix
determination method
IEA
1 reference
retrieved
18 July 2017
stated in
UniProt-GOA
curator
UniProt
UniProt ID
P12644
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
extracellular space
determination method
IDA
IEA
ISS
4 references
retrieved
18 July 2017
stated in
UniProt-GOA
curator
UniProt
UniProt ID
P12644
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
ISS
retrieved
18 July 2017
stated in
UniProt-GOA
curator
UniProt
UniProt ID
P12644
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
retrieved
18 July 2017
stated in
Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression
UniProt-GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IDA
endoplasmic reticulum lumen
determination method
TAS
1 reference
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
TAS
biological process
embryonic skeletal system morphogenesis
determination method
IEA
1 reference
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
negative regulation of T cell differentiation in thymus
determination method
IMP
1 reference
retrieved
18 July 2017
stated in
Bone morphogenetic protein 2/4 signaling regulates early thymocyte differentiation
UniProt-GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IMP
germ cell development
determination method
IEA
1 reference
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
skeletal system development
determination method
IEA
1 reference
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
mesenchymal cell differentiation involved in renal system development
determination method
IEA
1 reference
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
cardiac septum development
determination method
TAS
1 reference
retrieved
18 July 2017
stated in
Mutations in GATA4, NKX2.5, CRELD1, and BMP4 are infrequently found in patients with congenital cardiac septal defects
UniProt-GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
TAS
ureteric bud development
determination method
IDA
IEA
2 references
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
retrieved
18 July 2017
stated in
BMPs and BMP receptors in mouse metanephric development: in vivo and in vitro studies
UniProt-GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IDA
positive regulation of protein phosphorylation
determination method
IDA
IEA
2 references
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
retrieved
18 July 2017
stated in
Endogenous TGF-beta signaling suppresses maturation of osteoblastic mesenchymal cells.
UniProt-GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IDA
renal system process
determination method
IEA
1 reference
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
positive regulation of endothelial cell differentiation
determination method
IEA
1 reference
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
negative regulation of immature T cell proliferation in thymus
determination method
IMP
1 reference
retrieved
18 July 2017
stated in
Bone morphogenetic protein 2/4 signaling regulates early thymocyte differentiation
UniProt-GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IMP
bud elongation involved in lung branching
determination method
IEA
1 reference
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
tendon cell differentiation
determination method
ISS
IEA
2 references
retrieved
18 July 2017
stated in
UniProt-GOA
curator
UniProt
UniProt ID
P12644
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
ISS
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
anatomical structure formation involved in morphogenesis
determination method
IEA
1 reference
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
ureter epithelial cell differentiation
determination method
ISS
IEA
2 references
retrieved
18 July 2017
stated in
UniProt-GOA
curator
UniProt
UniProt ID
P12644
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
ISS
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
negative regulation of cell cycle
determination method
IDA
1 reference
retrieved
18 July 2017
stated in
Altered growth responses of pulmonary artery smooth muscle cells from patients with primary pulmonary hypertension to transforming growth factor-beta(1) and bone morphogenetic proteins
UniProt-GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IDA
mesenchymal to epithelial transition involved in metanephros morphogenesis
determination method
IDA
1 reference
retrieved
18 July 2017
stated in
BMP-4 affects the differentiation of metanephric mesenchyme and reveals an early anterior-posterior axis of the embryonic kidney
UniProt-GOA
curator
UniProt
UniProt ID
P12644
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IDA
trachea development
determination method
IDA
1 reference
retrieved
18 July 2017
stated in
Evidence from normal expression and targeted misexpression that bone morphogenetic protein (Bmp-4) plays a role in mouse embryonic lung morphogenesis
UniProt-GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IDA
post-embryonic development
determination method
IDA
IEA
2 references
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
retrieved
18 July 2017
stated in
Evidence from normal expression and targeted misexpression that bone morphogenetic protein (Bmp-4) plays a role in mouse embryonic lung morphogenesis
UniProt-GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IDA
monocyte differentiation
determination method
IDA
1 reference
retrieved
18 July 2017
stated in
Monocytic cells derived from human embryonic stem cells and fetal liver share common differentiation pathways and homeostatic functions
UniProt-GOA
curator
Developmental FunctionaL Annotation at Tufts
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IDA
specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway
determination method
IDA
2 references
retrieved
18 July 2017
stated in
BMP-4 affects the differentiation of metanephric mesenchyme and reveals an early anterior-posterior axis of the embryonic kidney
UniProt-GOA
curator
UniProt
UniProt ID
P12644
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IDA
retrieved
18 July 2017
stated in
Ureteric branching morphogenesis in BMP4 heterozygous mutant mice
UniProt-GOA
curator
UniProt
UniProt ID
P12644
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IDA
blood vessel endothelial cell proliferation involved in sprouting angiogenesis
determination method
IDA
1 reference
retrieved
18 July 2017
stated in
BMPER is an endothelial cell regulator and controls bone morphogenetic protein-4-dependent angiogenesis
UniProt-GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IDA
BMP signaling pathway involved in renal system segmentation
determination method
ISS
IEA
2 references
retrieved
18 July 2017
stated in
UniProt-GOA
curator
UniProt
UniProt ID
P12644
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
ISS
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
cranial suture morphogenesis
determination method
IEA
1 reference
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
mesonephros development
determination method
IEP
1 reference
retrieved
18 July 2017
stated in
Involvement of FGF and BMP family proteins and VEGF in early human kidney development
UniProt-GOA
curator
UniProt
UniProt ID
P12644
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEP
odontogenesis of dentin-containing tooth
determination method
IEA
1 reference
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
telencephalon regionalization
determination method
IEA
1 reference
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
negative regulation of chondrocyte differentiation
determination method
IEA
1 reference
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
blood vessel development
determination method
IEA
1 reference
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
negative regulation of mitotic nuclear division
determination method
IDA
1 reference
retrieved
18 July 2017
stated in
Antagonistic effects of bone morphogenetic protein-4 and -7 on renal mesangial cell proliferation induced by aldosterone through MAPK activation
UniProt-GOA
curator
UniProt
UniProt ID
P12644
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IDA
angiogenesis
determination method
IEA
1 reference
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
prostate gland morphogenesis
determination method
IEA
1 reference
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
positive regulation of ERK1 and ERK2 cascade
determination method
IEA
1 reference
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
smooth muscle tissue development
determination method
ISS
IEA
2 references
retrieved
18 July 2017
stated in
UniProt-GOA
curator
UniProt
UniProt ID
P12644
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
ISS
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
BMP signaling pathway involved in heart induction
determination method
IMP
1 reference
retrieved
18 July 2017
stated in
BMP-mediated inhibition of FGF signaling promotes cardiomyocyte differentiation of anterior heart field progenitors
UniProt-GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IMP
negative regulation of epithelial cell proliferation
determination method
IEA
1 reference
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
tissue development
determination method
IEA
1 reference
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
metanephric collecting duct development
determination method
ISS
IEA
2 references
retrieved
18 July 2017
stated in
UniProt-GOA
curator
UniProt
UniProt ID
P12644
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
ISS
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
inner ear receptor cell differentiation
determination method
IEA
1 reference
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
mesodermal cell fate determination
determination method
IEA
1 reference
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
metanephros development
determination method
IEA
1 reference
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
type B pancreatic cell development
determination method
IDA
1 reference
retrieved
18 July 2017
stated in
Bone morphogenetic proteins promote development of fetal pancreas epithelial colonies containing insulin-positive cells
UniProt-GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IDA
regulation of pathway-restricted SMAD protein phosphorylation
determination method
IDA
1 reference
retrieved
18 July 2017
stated in
BMPER is an endothelial cell regulator and controls bone morphogenetic protein-4-dependent angiogenesis
UniProt-GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IDA
negative regulation of cell proliferation
determination method
IDA
IEA
2 references
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
retrieved
18 July 2017
stated in
Bone morphogenetic proteins (BMPs) as regulators of dorsal forebrain development
UniProt-GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IDA
steroid hormone mediated signaling pathway
determination method
IMP
1 reference
retrieved
18 July 2017
stated in
Antagonistic effects of bone morphogenetic protein-4 and -7 on renal mesangial cell proliferation induced by aldosterone through MAPK activation
UniProt-GOA
curator
UniProt
UniProt ID
P12644
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IMP
mammary gland formation
determination method
IEA
1 reference
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
positive regulation of collagen biosynthetic process
determination method
IDA
1 reference
retrieved
18 July 2017
stated in
Noncanonical Wnt-4 signaling enhances bone regeneration of mesenchymal stem cells in craniofacial defects through activation of p38 MAPK
UniProt-GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IDA
renal system development
determination method
IEP
IEA
2 references
retrieved
18 July 2017
stated in
Immunohistochemical analysis of Sonic hedgehog signalling in normal human urinary tract development
UniProt-GOA
curator
UniProt
UniProt ID
P12644
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEP
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
negative regulation of myoblast differentiation
determination method
IDA
1 reference
retrieved
18 July 2017
stated in
Endogenous TGF-beta signaling suppresses maturation of osteoblastic mesenchymal cells.
UniProt-GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IDA
cell fate commitment
determination method
IEA
1 reference
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
common-partner SMAD protein phosphorylation
determination method
IDA
1 reference
retrieved
18 July 2017
stated in
Tumor suppressor FLCN inhibits tumorigenesis of a FLCN-null renal cancer cell line and regulates expression of key molecules in TGF-beta signaling
UniProt-GOA
curator
UniProt
UniProt ID
P12644
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IDA
glomerular visceral epithelial cell development
determination method
IEA
1 reference
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
SMAD protein signal transduction
determination method
IDA
IEA
2 references
retrieved
18 July 2017
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
retrieved
18 July 2017
stated in
Antagonistic effects of bone morphogenetic protein-4 and -7 on renal mesangial cell proliferation induced by aldosterone through MAPK activation
UniProt-GOA
curator
UniProt
UniProt ID
P12644
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IDA
ossification
determination method
IEA
1 reference
retrieved
18 July 2017
stated in
UniProt-GOA
curator
UniProt
UniProt ID
P12644
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P12644
determination method
IEA
activation of MAPKK activity
determination method
IDA
2 references
retrieved
18 July 2017
stated in
BMP4 induces HO-1 via a Smad-independent, p38MAPK-dependent pathway in pulmonary artery myocytes