Tumor suppressor FLCN inhibits tumorigenesis of a FLCN-null renal cancer cell line and regulates expression of key molecules in TGF-beta signaling (Q24329165)

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English	Tumor suppressor FLCN inhibits tumorigenesis of a FLCN-null renal cancer cell line and regulates expression of key molecules in TGF-beta signaling	scientific article

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scholarly article

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6 February 2020

Tumor suppressor FLCN inhibits tumorigenesis of a FLCN-null renal cancer cell line and regulates expression of key molecules in TGF-beta signaling (English)

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6 February 2020

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GOA release 2020-03-11

transforming growth factor beta 2

1 reference

GOA release 2020-03-11

Inhibin subunit beta A

1 reference

GOA release 2020-03-11

transforming growth factor beta 1

1 reference

GOA release 2020-03-11

bone morphogenetic protein 4

1 reference

GOA release 2020-03-11

positive regulation of transcription by RNA polymerase II

1 reference

GOA release 2020-03-11

cancer cell line

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based on heuristic

inferred from title

6

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6 February 2020

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Seung-Beom Hong

1

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6 February 2020

HyoungBin Oh

2

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6 February 2020

Vladimir A Valera

3

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6 February 2020

Jaime Stull

4

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6 February 2020

Duy-Tan Ngo

5

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6 February 2020

Maria J Merino

7

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6 February 2020

W Marston Linehan

8

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6 February 2020

Laura S Schmidt

9

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6 February 2020

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23 June 2010

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6 February 2020

Molecular Cancer

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6 February 2020

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6 February 2020

1

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160

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6 February 2020

Identification and characterization of a novel folliculin-interacting protein FNIP2

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19 March 2017

BHD mutations, clinical and molecular genetic investigations of Birt-Hogg-Dubé syndrome: a new series of 50 families and a review of published reports

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19 March 2017

Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

19 March 2017

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

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19 March 2017

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

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19 March 2017

Primer3 on the WWW for general users and for biologist programmers

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19 March 2017

Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2

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19 March 2017

Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys

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19 March 2017

Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dubé syndrome

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19 March 2017

Role of transforming growth factor-beta signaling in cancer

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

19 March 2017

Renal tumour suppressor function of the Birt-Hogg-Dubé syndrome gene product folliculin

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19 March 2017

The role of the Birt-Hogg-Dubé protein in mTOR activation and renal tumorigenesis

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19 March 2017

Deficiency of FLCN in mouse kidney led to development of polycystic kidneys and renal neoplasia

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19 March 2017

Activin signaling and its role in regulation of cell proliferation, apoptosis, and carcinogenesis

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19 March 2017

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

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7 April 2017

The UOK 257 cell line: a novel model for studies of the human Birt-Hogg-Dubé gene pathway

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27 September 2017

Activin A: autocrine regulator of kidney development and repair

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27 September 2017

Thrombospondin-1 expression in urothelial carcinoma: prognostic significance and association with p53 alterations, tumour angiogenesis and extracellular matrix components

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27 September 2017

Germline BHD-mutation spectrum and phenotype analysis of a large cohort of families with Birt-Hogg-Dubé syndrome

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27 September 2017

A germ-line insertion in the Birt-Hogg-Dubé (BHD) gene gives rise to the Nihon rat model of inherited renal cancer

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

27 September 2017

Clinical and genetic studies of Birt-Hogg-Dubé syndrome.

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27 September 2017

Thrombospondin 1 protein expression relates to good prognostic indices in ductal carcinoma in situ of the breast

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27 September 2017

Birt-Hogg-Dubé syndrome, a genodermatosis associated with spontaneous pneumothorax and kidney neoplasia, maps to chromosome 17p11.2.

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27 September 2017

Hereditary Multiple Fibrofolliculomas With Trichodiscomas and Acrochordons

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27 September 2017

TGF-beta receptor signaling

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30 May 2018

Hypermethylation of the thrombospondin-1 gene is associated with poor prognosis in penile squamous cell carcinoma.

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29 November 2018

The Birt-Hogg-Dube and tuberous sclerosis complex homologs have opposing roles in amino acid homeostasis in Schizosaccharomyces pombe.

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29 November 2018

The Drosophila homolog of the human tumor suppressor gene BHD interacts with the JAK-STAT and Dpp signaling pathways in regulating male germline stem cell maintenance

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29 November 2018

High frequency of somatic frameshift BHD gene mutations in Birt-Hogg-Dubé-associated renal tumors.

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29 November 2018

Loss of the Smad3 expression increases susceptibility to tumorigenicity in human gastric cancer.

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29 November 2018

A mutation in the canine BHD gene is associated with hereditary multifocal renal cystadenocarcinoma and nodular dermatofibrosis in the German Shepherd dog.

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Risk of renal and colonic neoplasms and spontaneous pneumothorax in the Birt-Hogg-Dubé syndrome.

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Birt-Hogg-Dubé syndrome: a novel marker of kidney neoplasia.

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Birt-Hogg-Dubé syndrome: clinical and genetic studies of 20 families

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Renal Tumors in the Birt-Hogg-Dubé Syndrome

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https://pubmed.ncbi.nlm.nih.gov/20573232

12 December 2020

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Somatic alterations of the DPC4 gene in human colorectal cancers in vivo

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Expression of Thrombospondin-1 in Resected Colorectal Liver Metastases Predicts Poor Prognosis

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12 December 2020

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10.1186/1476-4598-9-160

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Consolidated OpenCitations Corpus – April 2017

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6 February 2020

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9 September 2019

https://scigraph.springernature.com/pub.10.1186/1476-4598-9-160

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Consolidated OpenCitations Corpus – April 2017

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2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20573232%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

PubMed publication ID

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Consolidated OpenCitations Corpus – April 2017

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Europe PubMed Central

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6 February 2020

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