WFIKKN1 and WFIKKN2 bind growth factors TGFβ1, BMP2 and BMP4 but do not inhibit their signalling activity (Q24305801)

WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2

GOA release 2020-03-11

1 reference

transforming growth factor beta binding

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

László Patthy

4

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author name string

György Szláma

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Katalin Kondás

2

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Mária Trexler

The transforming growth factor-beta superfamily of receptors

3

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language of work or name

English

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publication date

December 2010

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published in

FEBS Journal

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volume

277

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page(s)

5040-50

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issue

24

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cites work

1 reference

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GDF-8 propeptide binds to GDF-8 and antagonizes biological activity by inhibiting GDF-8 receptor binding

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GDF11 forms a bone morphogenetic protein 1-activated latent complex that can modulate nerve growth factor-induced differentiation of PC12 cells

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The role of proteases in transforming growth factor-beta activation

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Developmental roles of the BMP1/TLD metalloproteinases.

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TGF-beta receptors and signalling mechanisms

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Signaling via hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors

21 January 2018

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BMP and BMP inhibitors in bone

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Both WFIKKN1 and WFIKKN2 have high affinity for growth and differentiation factors 8 and 11

21 January 2018

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A human protein containing multiple types of protease-inhibitory modules

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Distinct expression pattern of two related human proteins containing multiple types of protease-inhibitory modules

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Regulation of myostatin in vivo by growth and differentiation factor-associated serum protein-1: a novel protein with protease inhibitor and follistatin domains

21 January 2018

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OC29 is preferentially expressed in the presumptive sensory organ region of the otocyst

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Grading the commercial optical biosensor literature-Class of 2008: 'The Mighty Binders'.

21 January 2018

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Local inhibition and long-range enhancement of Dpp signal transduction by Sog.

21 January 2018

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The crossveinless gene encodes a new member of the Twisted gastrulation family of BMP-binding proteins which, with Short gastrulation, promotes BMP signaling in the crossveins of the Drosophila wing.

21 January 2018

1 reference

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Crossveinless 2 is an essential positive feedback regulator of Bmp signaling during zebrafish gastrulation.

21 January 2018

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crm-1 facilitates BMP signaling to control body size in Caenorhabditis elegans.

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Ectopic noggin blocks sensory and nonsensory organ morphogenesis in the chicken inner ear.

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A rapid and sensitive bioassay to measure bone morphogenetic protein activity

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The soluble exoplasmic domain of the type II transforming growth factor (TGF)-beta receptor. A heterogeneously glycosylated protein with high affinity and selectivity for TGF-beta ligands

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Interaction between soluble type I receptor for bone morphogenetic protein and bone morphogenetic protein-4.

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Characterization and cloning of a receptor for BMP-2 and BMP-4 from NIH 3T3 cells.

21 January 2018

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BMP-3 and BMP-6 structures illuminate the nature of binding specificity with receptors

21 January 2018

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An assay for transforming growth factor-beta using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct

21 January 2018

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