ABL proto-oncogene 1, non-receptor tyrosine kinase (Q587961)

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mammalian protein found in Homo sapiens
  • Abelson tyrosine-protein kinase 1
  • p150
  • ABL1
  • bcr/c-abl oncogene protein
  • proto-oncogene c-Abl
  • v-abl Abelson murine leukemia viral oncogene homolog 1
  • ABL protooncogene 1 nonreceptor tyrosine kinase
  • c-abl oncogene 1, receptor tyrosine kinase
  • tyrosine-protein kinase
  • truncated ABL protooncogene 1 nonreceptor tyrosine kinase
  • tyrosine-protein kinase ABL1
  • proto-oncogene tyrosine-protein kinase ABL1
  • Abelson murine leukemia viral oncogene homolog 1
edit
Language Label Description Also known as
English
ABL proto-oncogene 1, non-receptor tyrosine kinase
mammalian protein found in Homo sapiens
  • Abelson tyrosine-protein kinase 1
  • p150
  • ABL1
  • bcr/c-abl oncogene protein
  • proto-oncogene c-Abl
  • v-abl Abelson murine leukemia viral oncogene homolog 1
  • ABL protooncogene 1 nonreceptor tyrosine kinase
  • c-abl oncogene 1, receptor tyrosine kinase
  • tyrosine-protein kinase
  • truncated ABL protooncogene 1 nonreceptor tyrosine kinase
  • tyrosine-protein kinase ABL1
  • proto-oncogene tyrosine-protein kinase ABL1
  • Abelson murine leukemia viral oncogene homolog 1

Statements

part of
image
Protein ABL1 PDB 1ab2.png
793 × 521; 173 KB
0 references
molecular function
protein binding
determination method
IPI
46 references
retrieved
8 April 2019
stated in
Regulation of Rad51 function by c-Abl in response to DNA damage
GOA
curator
UniProt
UniProt protein ID
P00519
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
Fibroblast growth factor receptor 1 oncogene partner as a novel prognostic biomarker and therapeutic target for lung cancer
GOA
curator
UniProt
UniProt protein ID
P00519
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activity
GOA
curator
UniProt
UniProt protein ID
P00519
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
Cloning, mapping, and characterization of the human sorbin and SH3 domain containing 1 (SORBS1) gene: a protein associated with c-Abl during insulin signaling in the hepatoma cell line Hep3B
GOA
curator
UniProt
UniProt protein ID
P00519
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
Abelson phosphorylation of CLASP2 modulates its association with microtubules and actin
GOA
curator
UniProt
UniProt protein ID
P00519
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaks
GOA
curator
UniProt
UniProt protein ID
P00519
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
c-Abl tyrosine kinase regulates caspase-9 autocleavage in the apoptotic response to DNA damage
GOA
curator
UniProt
UniProt protein ID
P00519
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
NESH (Abi-3) is present in the Abi/WAVE complex but does not promote c-Abl-mediated phosphorylation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
Consequences of Shb and c-Abl interactions for cell death in response to various stress stimuli
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
A quantitative protein interaction network for the ErbB receptors using protein microarrays
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
Phosphorylation of DNA topoisomerase I by the c-Abl tyrosine kinase confers camptothecin sensitivity
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
JNK phosphorylation of 14-3-3 proteins regulates nuclear targeting of c-Abl in the apoptotic response to DNA damage
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
Abl kinase interacts with and phosphorylates vinexin
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
Differential protein-protein interactions of LRRK1 and LRRK2 indicate roles in distinct cellular signaling pathways
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
Physical and functional interaction between hMSH5 and c-Abl
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
Evidence for a direct involvement of hMSH5 in promoting ionizing radiation induced apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
Characterization of p87C3G, a novel, truncated C3G isoform that is overexpressed in chronic myeloid leukemia and interacts with Bcr-Abl
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
RIN1 is an ABL tyrosine kinase activator and a regulator of epithelial-cell adhesion and migration
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
c-Abl tyrosine kinase interacts with MAVS and regulates innate immune response
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
Protein binding and signaling properties of RIN1 suggest a unique effector function
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
Interaction between ATM protein and c-Abl in response to DNA damage
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
c-Abl kinase is required for beta 2 integrin-mediated neutrophil adhesion
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
Cdo binds Abl to promote p38alpha/beta mitogen-activated protein kinase activity and myogenic differentiation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
Allosteric inhibition of the nonMyristoylated c-Abl tyrosine kinase by phosphopeptides derived from Abi1/Hssh3bp1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
MutS homologue hMSH5: role in cisplatin-induced DNA damage response
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
Cockayne syndrome protein B interacts with and is phosphorylated by c-Abl tyrosine kinase
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaks
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
BCR-ABL uncouples canonical JAK2-STAT5 signaling in chronic myeloid leukemia
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
Identification of a candidate human spectrin Src homology 3 domain-binding protein suggests a general mechanism of association of tyrosine kinases with the spectrin-based membrane skeleton
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
Structure of a regulatory complex involving the Abl SH3 domain, the Crk SH2 domain, and a Crk-derived phosphopeptide
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
SH2/SH3 adaptor proteins can link tyrosine kinases to a Ste20-related protein kinase, HPK1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
Bcr-Abl stabilizes beta-catenin in chronic myeloid leukemia through its tyrosine phosphorylation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
MUC1 oncoprotein blocks nuclear targeting of c-Abl in the apoptotic response to DNA damage
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
ABL2 suppresses FLT3-ITD-induced cell proliferation through negative regulation of AKT signaling.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
Cloning, mapping, and characterization of the human sorbin and SH3 domain containing 1 (SORBS1) gene: a protein associated with c-Abl during insulin signaling in the hepatoma cell line Hep3B
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
Isolation of hNap1BP which interacts with human Nap1 (NCKAP1) whose expression is down-regulated in Alzheimer's disease
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
Abi1/Hssh3bp1 pY213 links Abl kinase signaling to p85 regulatory subunit of PI-3 kinase in regulation of macropinocytosis in LNCaP cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK
GOA
curator
Critical Assessment of Protein Function Annotation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
Structure of a regulatory complex involving the Abl SH3 domain, the Crk SH2 domain, and a Crk-derived phosphopeptide
GOA
curator
Critical Assessment of Protein Function Annotation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
retrieved
8 April 2019
stated in
Glutathione peroxidase 1 is regulated by the c-Abl and Arg tyrosine kinases
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IPI
protein tyrosine kinase activity
determination method
IEA
TAS
IDA
EXP
IMP
14 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
TAS
retrieved
8 April 2019
stated in
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
TAS
retrieved
8 April 2019
stated in
Abelson phosphorylation of CLASP2 modulates its association with microtubules and actin
GOA
curator
UniProt
UniProt protein ID
P00519
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IMP
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P00519
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IEA
retrieved
8 April 2019
stated in
Protein binding and signaling properties of RIN1 suggest a unique effector function
GOA
curator
UniProt
UniProt protein ID
P00519
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IDA
retrieved
8 April 2019
stated in
Fibroblast growth factor receptor 1 oncogene partner as a novel prognostic biomarker and therapeutic target for lung cancer
GOA
curator
UniProt
UniProt protein ID
P00519
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IDA
retrieved
8 April 2019
stated in
c-Abl tyrosine kinase regulates caspase-9 autocleavage in the apoptotic response to DNA damage
GOA
curator
UniProt
UniProt protein ID
P00519
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IDA
retrieved
8 April 2019
stated in
Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activity
GOA
curator
UniProt
UniProt protein ID
P00519
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IDA
retrieved
8 April 2019
stated in
Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective function
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IDA
retrieved
8 April 2019
stated in
Werner syndrome protein phosphorylation by abl tyrosine kinase regulates its activity and distribution
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IDA
retrieved
8 April 2019
stated in
Functional interaction between c-Abl and the p21-activated protein kinase gamma-PAK
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IDA
retrieved
8 April 2019
stated in
Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
EXP
cell component
nucleus
determination method
NAS
IDA
TAS
IEA
6 references
retrieved
3 January 2017
stated in
ABL tyrosine kinases: evolution of function, regulation, and specificity
GOA
curator
UniProt
UniProt protein ID
P00519
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P00519
determination method
TAS
retrieved
3 January 2017
stated in
A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle
GOA
curator
UniProt
UniProt protein ID
P00519
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P00519
determination method
NAS
retrieved
3 January 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P00519
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P00519
determination method
IEA
retrieved
3 January 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P00519
determination method
IEA
retrieved
3 January 2017
stated in
Fibroblast growth factor receptor 1 oncogene partner as a novel prognostic biomarker and therapeutic target for lung cancer
GOA
curator
UniProt
UniProt protein ID
P00519
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P00519
determination method
IDA
retrieved
3 January 2017
stated in
Cockayne syndrome protein B interacts with and is phosphorylated by c-Abl tyrosine kinase
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P00519
determination method
IDA
nucleus
determination method
IDA
IEA
ISS
NAS
TAS
8 references
retrieved
8 April 2019
stated in
ABL tyrosine kinases: evolution of function, regulation, and specificity
GOA
curator
UniProt
UniProt protein ID
P00519
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
TAS
retrieved
8 April 2019
stated in
A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle
GOA
curator
UniProt
UniProt protein ID
P00519
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
NAS
retrieved
8 April 2019
stated in
GOA
curator
ARUK-UCL
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
ISS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P00519
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IEA
retrieved
8 April 2019
stated in
Fibroblast growth factor receptor 1 oncogene partner as a novel prognostic biomarker and therapeutic target for lung cancer
GOA
curator
UniProt
UniProt protein ID
P00519
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IDA
retrieved
8 April 2019
stated in
Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation
GOA
curator
UniProt
UniProt protein ID
P00519
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IDA
retrieved
8 April 2019
stated in
Cockayne syndrome protein B interacts with and is phosphorylated by c-Abl tyrosine kinase
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IDA
biological process
peptidyl-tyrosine phosphorylation
determination method
IDA
TAS
IMP
IEA
9 references
retrieved
8 April 2019
stated in
Structure and Function of Parkin, PINK1, and DJ-1, the Three Musketeers of Neuroprotection
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
TAS
retrieved
8 April 2019
stated in
Oxidative stress-induced signaling pathways implicated in the pathogenesis of Parkinson's disease
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
TAS
retrieved
8 April 2019
stated in
Abelson phosphorylation of CLASP2 modulates its association with microtubules and actin
GOA
curator
UniProt
UniProt protein ID
P00519
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IMP
retrieved
8 April 2019
stated in
Differential regulation of PKD isoforms in oxidative stress conditions through phosphorylation of a conserved Tyr in the P+1 loop
GOA
curator
UniProt
UniProt protein ID
P00519
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IMP
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IEA
retrieved
8 April 2019
stated in
Protein binding and signaling properties of RIN1 suggest a unique effector function
GOA
curator
UniProt
UniProt protein ID
P00519
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IDA
retrieved
8 April 2019
stated in
Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activity
GOA
curator
UniProt
UniProt protein ID
P00519
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IDA
retrieved
8 April 2019
stated in
Interaction between protein kinase C delta and the c-Abl tyrosine kinase in the cellular response to oxidative stress
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IDA
retrieved
8 April 2019
stated in
Functional interaction between c-Abl and the p21-activated protein kinase gamma-PAK
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00519
determination method
IDA
physically interacts with
Gene Atlas image
PBB GE ABL1 202123 s at fs.png
732 × 530; 11 KB
0 references

Identifiers

Microsoft Academic ID
125418893
0 references
2910835860
0 references
PDB structure ID
 
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                  Retrieved from "https://www.wikidata.org/w/index.php?title=Q587961&oldid=2022902461"