Allosteric inhibition of the nonMyristoylated c-Abl tyrosine kinase by phosphopeptides derived from Abi1/Hssh3bp1 (Q24321968)

10

object named as

Leszek Kotula

0 references

Asim K Debnath

8

object named as

Asim K Debnath

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author name string

Xiaoling Xiong

1

0 references

Ping Cui

2

0 references

Sajjad Hossain

3

0 references

Rong Xu

4

0 references

Brian Warner

5

0 references

Xinhua Guo

6

0 references

Xiuli An

Biochimica et Biophysica Acta

7

0 references

language of work or name

English

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publication date

May 2008

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published in

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volume

1783

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issue

5

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page(s)

737-47

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cites work

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Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activity

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Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation

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c-Src binds alpha II spectrin's Src homology 3 (SH3) domain and blocks calpain susceptibility by phosphorylating Tyr1176

19 March 2017

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Loss of expression of human spectrin src homology domain binding protein 1 is associated with 10p loss in human prostatic adenocarcinoma

19 March 2017

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Drosophila abelson interacting protein (dAbi) is a positive regulator of abelson tyrosine kinase activity

19 March 2017

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Essential roles for the Abl and Arg tyrosine kinases in neurulation

19 March 2017

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Two distinct phosphorylation pathways have additive effects on Abl family kinase activation

19 March 2017

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Catalytic specificity of protein-tyrosine kinases is critical for selective signalling

7 April 2017

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Organization of the SH3-SH2 unit in active and inactive forms of the c-Abl tyrosine kinase

7 April 2017

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A common phosphotyrosine signature for the Bcr-Abl kinase

27 September 2017

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Allosteric inhibitors of Bcr-abl-dependent cell proliferation

27 September 2017

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The crystal structure of a c-Src complex in an active conformation suggests possible steps in c-Src activation

27 September 2017

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Regulation of the c-Abl and Bcr-Abl tyrosine kinases

27 September 2017

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Controlling Abl: auto-inhibition and co-inhibition?

27 September 2017

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Chronic Myeloid Leukemia — Advances in Biology and New Approaches to Treatment

27 September 2017

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Regulation of F-actin-dependent processes by the Abl family of tyrosine kinases

27 September 2017

1 reference

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A myristoyl/phosphotyrosine switch regulates c-Abl

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2435598

27 September 2017

Autoinhibition of c-Abl

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2435598

Inhibition of v-Abl transformation in 3T3 cells overexpressing different forms of the Abelson interactor protein Abi-1.

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2435598

Blot overlays with 32P-labeled fusion proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2435598

Human spectrin Src homology 3 domain binding protein 1 regulates macropinocytosis in NIH 3T3 cells.

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2435598

Inhibition of the Abl protein-tyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2435598

Enhanced affinities and specificities of consolidated ligands for the Src homology (SH) 3 and SH2 domains of Abelson protein-tyrosine kinase.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2435598

Abl-interactor-1, a novel SH3 protein binding to the carboxy-terminal portion of the Abl protein, suppresses v-abl transforming activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2435598

Point mutations in the abl SH2 domain coordinately impair phosphotyrosine binding in vitro and transforming activity in vivo

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2435598

Circumventing Resistance to Kinase-Inhibitor Therapy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2435598

Cancer: Escape from inhibition

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2435598

Mechanisms of autoinhibition and STI-571/imatinib resistance revealed by mutagenesis of BCR-ABL.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2435598

BCR-ABL gene mutations in relation to clinical resistance of Philadelphia-chromosome-positive leukaemia to STI571: a prospective study

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2435598

Solute perturbation of protein fluorescence. Quenching of the tryptophyl fluorescence of model compounds and of lysozyme by iodide ion

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18328268

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

c-Abl has high intrinsic tyrosine kinase activity that is stimulated by mutation of the Src homology 3 domain and by autophosphorylation at two distinct regulatory tyrosines

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18328268

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Chronic myelogenous leukemia

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18328268