The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization (Q24294830)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20697350%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20697350%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

Non-catalytic region of tyrosine kinase adaptor protein 1

1 reference

Abl interactor 1

1 reference

WASP family, member 2

1 reference

author

Bjoern Titz

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20697350%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Thomas Graeber

6

1 reference

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9 February 2020

author name string

T Low

2

1 reference

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9 February 2020

E Komisopoulou

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20697350%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

S S Chen

4

1 reference

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9 February 2020

L Rubbi

5

1 reference

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9 February 2020

language of work or name

English

0 references

publication date

9 August 2010

1 reference

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9 February 2020

1 reference

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9 February 2020

volume

29

1 reference

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9 February 2020

page(s)

5895-5910

1 reference

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9 February 2020

issue

44

1 reference

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describes a project that uses

9 February 2020

Cytoscape

1 reference

9 June 2022

https://europepmc.org/search?query=(METHODS:'Cytoscape')

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein

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Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK

19 March 2017

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A common LRRK2 mutation in idiopathic Parkinson's disease

19 March 2017

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Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation

19 March 2017

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Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease

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Non-redundant role of Shc in Erk activation by cytoskeletal reorganization

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Protein complexes and functional modules in molecular networks

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A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signaling

19 March 2017

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STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes

19 March 2017

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Critical role for Gab2 in transformation by BCR/ABL

19 March 2017

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ARAP1: a point of convergence for Arf and Rho signaling

19 March 2017

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The intersectin 2 adaptor links Wiskott Aldrich Syndrome protein (WASp)-mediated actin polymerization to T cell antigen receptor endocytosis

19 March 2017

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p62(dok), a negative regulator of Ras and mitogen-activated protein kinase (MAPK) activity, opposes leukemogenesis by p210(bcr-abl)

19 March 2017

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The Grb2 binding site is required for the induction of chronic myeloid leukemia-like disease in mice by the Bcr/Abl tyrosine kinase

19 March 2017

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Mouse VAP33 is associated with the endoplasmic reticulum and microtubules

19 March 2017

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CMS: an adapter molecule involved in cytoskeletal rearrangements

19 March 2017

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BCR/ABL-induced leukemogenesis causes phosphorylation of Hef1 and its association with Crkl

19 March 2017

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The SH2/SH3 domain-containing protein GRB2 interacts with tyrosine-phosphorylated IRS1 and Shc: implications for insulin control of ras signalling

19 March 2017

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Crkl is the major tyrosine-phosphorylated protein in neutrophils from patients with chronic myelogenous leukemia

19 March 2017

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A VAMP-binding protein from Aplysia required for neurotransmitter release

19 March 2017

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Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia

19 March 2017

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From molecular to modular cell biology

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7 April 2017

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PhosphoSite: A bioinformatics resource dedicated to physiological protein phosphorylation

7 April 2017

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Maximal entropy inference of oncogenicity from phosphorylation signaling.

7 April 2017

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Identification of DOK genes as lung tumor suppressors

27 September 2017

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A BCR-ABL mutant lacking direct binding sites for the GRB2, CBL and CRKL adapter proteins fails to induce leukemia in mice

27 September 2017

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LRRK2 modulates vulnerability to mitochondrial dysfunction in Caenorhabditis elegans

27 September 2017

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JAK mutations in high-risk childhood acute lymphoblastic leukemia

27 September 2017

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Caenorhabditits elegans LRK-1 and PINK-1 act antagonistically in stress response and neurite outgrowth

27 September 2017

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Dynamic modularity in protein interaction networks predicts breast cancer outcome

27 September 2017

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Transient potent BCR-ABL inhibition is sufficient to commit chronic myeloid leukemia cells irreversibly to apoptosis

27 September 2017

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The 14-3-3 proteins: integrators of diverse signaling cues that impact cell fate and cancer development

27 September 2017

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ARAP1 regulates endocytosis of EGFR.

27 September 2017

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ARAP1 regulates EGF receptor trafficking and signalling.

27 September 2017

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Reinduction platform for children with first marrow relapse of acute lymphoblastic Leukemia: A Children's Oncology Group Study[corrected]

27 September 2017

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Wild-type LRRK2 but not its mutant attenuates stress-induced cell death via ERK pathway

27 September 2017

1 reference

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Understanding eukaryotic linear motifs and their role in cell signaling and regulation.

27 September 2017

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Abi1 gene silencing by short hairpin RNA impairs Bcr-Abl-induced cell adhesion and migration in vitro and leukemogenesis in vivo

27 September 2017

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The chaperone activity of heat shock protein 90 is critical for maintaining the stability of leucine-rich repeat kinase 2.

27 September 2017

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Quantitative proteomic analysis of protein complexes: concurrent identification of interactors and their state of phosphorylation

27 September 2017

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The Shc-binding site of the betac subunit of the GM-CSF/IL-3/IL-5 receptors is a negative regulator of hematopoiesis

27 September 2017

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Important therapeutic targets in chronic myelogenous leukemia

27 September 2017

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Dynamic control of signaling by modular adaptor proteins

27 September 2017

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New therapeutic strategies for the treatment of acute lymphoblastic leukaemia

27 September 2017

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Molecular chaperones and protein kinase quality control.

27 September 2017

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Phosphorylation of the ATP-binding loop directs oncogenicity of drug-resistant BCR-ABL mutants

27 September 2017

1 reference

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Targeting multiple kinase pathways in leukemic progenitors and stem cells is essential for improved treatment of Ph+ leukemia in mice.

27 September 2017

1 reference

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An efficient tandem affinity purification procedure for interaction proteomics in mammalian cells

27 September 2017

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Peptides mediating interaction networks: new leads at last

27 September 2017

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A common phosphotyrosine signature for the Bcr-Abl kinase

27 September 2017

1 reference

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Pragmin, a novel effector of Rnd2 GTPase, stimulates RhoA activity.

27 September 2017

1 reference

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LRRK1 protein kinase activity is stimulated upon binding of GTP to its Roc domain

27 September 2017

1 reference

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Identification of novel mammalian growth regulatory factors by genome-scale quantitative image analysis

27 September 2017

1 reference

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Mechanisms of BCR-ABL in the pathogenesis of chronic myelogenous leukaemia

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5308218

Comparative analysis of two clinically active BCR-ABL kinase inhibitors reveals the role of conformation-specific binding in resistance

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5308218

Role of Dok-1 and Dok-2 in leukemia suppression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5308218

Purification and architecture of the ubiquitous Wave complex

27 September 2017

1 reference

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The BCR-ABL story: bench to bedside and back

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5308218

Effects of deficiencies of STAMs and Hrs, mammalian class E Vps proteins, on receptor downregulation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5308218

Tyrosine phosphorylation-dependent and -independent role of Shc in the regulation of IGF-1-induced mitogenesis and glycogen synthesis.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5308218

Crk family adaptors-signalling complex formation and biological roles

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5308218

Activation of Rho-dependent cell spreading and focal adhesion biogenesis by the v-Crk adaptor protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5308218

Structure of the IRS-1 PTB domain bound to the juxtamembrane region of the insulin receptor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5308218

BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5308218

Identification of CRKL as the constitutively phosphorylated 39-kD tyrosine phosphoprotein in chronic myelogenous leukemia cells

27 September 2017

1 reference

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Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5308218

Alternative signals to RAS for hematopoietic transformation by the BCR-ABL oncogene

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5308218

Activation of aortic endothelial cells by oxidized phospholipids: a phosphoproteomic analysis

27 September 2017

1 reference

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Identifying specific protein interaction partners using quantitative mass spectrometry and bead proteomes

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5308218

Differential regulation of adapter proteins Dok2 and Dok1 in platelets, leading to an association of Dok2 with integrin alphaIIbbeta3.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5308218

c-Abl interacts with the WAVE2 signaling complex to induce membrane ruffling and cell spreading

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5308218

Role of Dok-1 and Dok-2 in myeloid homeostasis and suppression of leukemia

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5308218

The coiled-coil domain and Tyr177 of bcr are required to induce a murine chronic myelogenous leukemia-like disease by bcr/abl.

30 May 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.331

BCR/ABL P190 transgenic mice develop leukemia in the absence of Crkl

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.331

LRRK2 enhances oxidative stress-induced neurotoxicity via its kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.331

Requirement of Src kinases Lyn, Hck and Fgr for BCR-ABL1-induced B-lymphoblastic leukemia but not chronic myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.331

Signal maps for mass spectrometry-based comparative proteomics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.331

Functional cooperation among Ras, STAT5, and phosphatidylinositol 3-kinase is required for full oncogenic activities of BCR/ABL in K562 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.331

Role for the Abi/wave protein complex in T cell receptor-mediated proliferation and cytoskeletal remodeling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.331

Dok-1 and Dok-2 are negative regulators of T cell receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.331

31 March 2020

Identifiers

DOI

10.1038/ONC.2010.331

2 references

Consolidated OpenCitations Corpus – April 2017

962978

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20697350%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 February 2020

1051560261

0 references

962978

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20697350%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

2 references

Consolidated OpenCitations Corpus – April 2017

962978

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20697350%20AND%20SRC:MED&resulttype=core&format=json