Engineering de novo reciprocal chromosomal translocations associated with Mll to replicate primary events of human cancer (Q58420389)

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4 November 2019

title

Engineering de novo reciprocal chromosomal translocations associated with Mll to replicate primary events of human cancer (English)

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4 November 2019

4

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4 November 2019

Terence Rabbitts

7

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4 November 2019

author name string

Alan Forster

1

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4 November 2019

Richard Pannell

2

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4 November 2019

Lesley F Drynan

3

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4 November 2019

Emma C Collins

5

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4 November 2019

Angelika Daser

6

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4 November 2019

publication date

1 May 2003

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4 November 2019

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4 November 2019

volume

3

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4 November 2019

page(s)

449-458

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4 November 2019

issue

5

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Transgenic models of lymphoid neoplasia and development of a pan-hematopoietic vector

4 November 2019

cites work

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7 January 2021

Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins

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Inducible chromosomal translocation of AML1 and ETO genes through Cre/loxP-mediated recombination in the mouse.

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7 January 2021

The promiscuous MLL gene links chromosomal translocations to cellular differentiation and tumour tropism

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7 January 2021

Inter-chromosomal recombination of Mll and Af9 genes mediated by cre-loxP in mouse development.

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7 January 2021

Acute leukemias of different lineages have similar MLL gene fusions encoding related chimeric proteins resulting from chromosomal translocation.

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7 January 2021

An Mll-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: a method to create fusion oncogenes

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7 January 2021

A trithorax-like gene is interrupted by chromosome 11q23 translocations in acute leukaemias

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7 January 2021

The mll-AF9 gene fusion in mice controls myeloproliferation and specifies acute myeloid leukaemogenesis

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7 January 2021

Tumorigenesis in mice with a fusion of the leukaemia oncogene Mll and the bacterial lacZ gene.

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7 January 2021

Acute mixed-lineage leukemia t(4;11)(q21;q23) generates an MLL-AF4 fusion product

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7 January 2021

Acute leukemia: a pediatric perspective

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7 January 2021

Pathways of chromosome alteration in human epithelial cancers.

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7 January 2021

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

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7 January 2021

In utero rearrangements in the trithorax-related oncogene in infant leukaemias.

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7 January 2021

The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene

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7 January 2021

Acute leukemia with promyelocytic features in PML/RARalpha transgenic mice

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7 January 2021

Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia

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7 January 2021

Transgenic mice for the preparation of hygromycin-resistant primary embryonic fibroblast feeder layers for embryonic stem cell selections

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7 January 2021

Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors

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7 January 2021

Bethesda proposals for classification of nonlymphoid hematopoietic neoplasms in mice

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7 January 2021

Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL.

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7 January 2021

Diversity and rearrangement of the human T cell rearranging gamma genes: nine germ-line variable genes belonging to two subgroups.

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7 January 2021

Transgenic mice for the preparation of puromycin-resistant primary embryonic fibroblast feeder layers for embryonic stem cell selection

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7 January 2021

Oncogenic transcription factors in the human acute leukemias

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7 January 2021

Chromosomal translocations in human cancer.

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7 January 2021

The critical role of chromosome translocations in human leukemias.

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7 January 2021

MLL-ENL cooperates with SCF to transform primary avian multipotent cells.

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7 January 2021

The oncogenic capacity of HRX-ENL requires the transcriptional transactivation activity of ENL and the DNA binding motifs of HRX.

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7 January 2021

A site-directed chromosomal translocation induced in embryonic stem cells by Cre-loxP recombination.

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7 January 2021

Rearrangement of the MLL gene in acute lymphoblastic and acute myeloid leukemias with 11q23 chromosomal translocations

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7 January 2021

Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias

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7 January 2021

Cre-mediated site-specific translocation between nonhomologous mouse chromosomes

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7 January 2021

The oncogenic cysteine-rich LIM domain protein rbtn2 is essential for erythroid development

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7 January 2021

The T cell leukemia LIM protein Lmo2 is necessary for adult mouse hematopoiesis.

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7 January 2021

Embryonic lethality and impairment of haematopoiesis in mice heterozygous for an AML1-ETO fusion gene.

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7 January 2021

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Identifiers

DOI

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4 November 2019

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