Chromosomal translocations in human cancer. (Q52512616)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7969446%20AND%20SRC:MED&resulttype=core&format=json

29 October 2019

title

Chromosomal translocations in human cancer (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7969446%20AND%20SRC:MED&resulttype=core&format=json

29 October 2019

1

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29 October 2019

author name string

Rabbitts TH

series ordinal

1

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2 May 2018

http://europepmc.org/abstract/MED/7969446

publication date

1 November 1994

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29 October 2019

language of work or name

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7969446%20AND%20SRC:MED&resulttype=core&format=json

29 October 2019

volume

372

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7969446%20AND%20SRC:MED&resulttype=core&format=json

29 October 2019

issue

6502

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29 October 2019

page(s)

143-149

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publication type of scholarly work

29 October 2019

review article

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Localization of human immunoglobulin kappa light chain variable region genes to the short arm of chromosome 2 by in situ hybridization.

cites work

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7 January 2021

Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc

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7 January 2021

Association of Myn, the murine homolog of Max, with c-Myc stimulates methylation-sensitive DNA binding and ras cotransformation

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7 January 2021

Mad: a heterodimeric partner for Max that antagonizes Myc transcriptional activity

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7 January 2021

Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites

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7 January 2021

Oncogenic activity of the c-Myc protein requires dimerization with Max.

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7 January 2021

Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease

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7 January 2021

bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes

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7 January 2021

bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship

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7 January 2021

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

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7 January 2021

Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species

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7 January 2021

Deregulation of a Homeobox Gene, HOX11, by the t(10;14) in T Cell Leukemia

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7 January 2021

HOX11, a homeobox-containing T-cell oncogene on human chromosome 10q24

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7 January 2021

The HOX11 gene encodes a DNA-binding nuclear transcription factor belonging to a distinct family of homeobox genes

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7 January 2021

Enhancer-binding activity of the tal-1 oncoprotein in association with the E47/E12 helix-loop-helix proteins

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7 January 2021

Structure of the carboxy-terminal LIM domain from the cysteine rich protein CRP

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7 January 2021

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7 January 2021

The LIM protein RBTN2 and the basic helix-loop-helix protein TAL1 are present in a complex in erythroid cells

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7 January 2021

The oncogenic cysteine-rich LIM domain protein rbtn2 is essential for erythroid development

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7 January 2021

Translocation of c-abl oncogene correlates with the presence of a Philadelphia chromosome in chronic myelocytic leukaemia

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7 January 2021

A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL

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7 January 2021

Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor

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7 January 2021

Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation

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7 January 2021

Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma

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7 January 2021

Pbx1 is converted into a transcriptional activator upon acquiring the N-terminal region of E2A in pre-B-cell acute lymphoblastoid leukemia

1 reference

7 January 2021

Hlf, a novel hepatic bZIP protein, shows altered DNA-binding properties following fusion to E2A in t(17;19) acute lymphoblastic leukemia

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7 January 2021

Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia

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7 January 2021

A trithorax-like gene is interrupted by chromosome 11q23 translocations in acute leukaemias

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7 January 2021

The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene

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7 January 2021

Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias

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7 January 2021

Acute leukemias of different lineages have similar MLL gene fusions encoding related chimeric proteins resulting from chromosomal translocation.

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7 January 2021

Characterization of an inversion on the long arm of chromosome 10 juxtaposing D10S170 and RET and creating the oncogenic sequence RET/PTC.

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7 January 2021

Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours

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7 January 2021

Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma

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7 January 2021

Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma

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7 January 2021

Rearrangement of the PAX3 paired box gene in the paediatric solid tumour alveolar rhabdomyosarcoma

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7 January 2021

Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma

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7 January 2021

Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma

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7 January 2021

Erythroleukemia induction by Friend murine leukemia virus: insertional activation of a new member of the ets gene family, Fli-1, closely linked to c-ets-1.

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7 January 2021

Combinatorial generation of variable fusion proteins in the Ewing family of tumours.

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7 January 2021

Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation.

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7 January 2021

A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS-family transcription factor, ERG

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7 January 2021

EWS and ATF-1 gene fusion induced by t(12;22) translocation in malignant melanoma of soft parts

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7 January 2021

Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A.

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7 January 2021

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7 January 2021

CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription

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7 January 2021

Transcriptional activation by TAL1 and FUS-CHOP proteins expressed in acute malignancies as a result of chromosomal abnormalities.

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7 January 2021

The der(11) chromosome contains the critical breakpoint junction in the 4;11, 9;11, and 11;19 translocations in acute leukemia

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7 January 2021

Gene encoding the alpha chain of the T-cell receptor is moved immediately downstream of c-myc in a chromosomal 8;14 translocation in a cell line from a human T-cell leukemia

1 reference

7 January 2021

A chromosome 12 coding region is juxtaposed to the MYC protooncogene locus in a t(8;12)(q24;q22) translocation in a case of B-cell chronic lymphocytic leukemia

1 reference

7 January 2021

lyl-1, a novel gene altered by chromosomal translocation in T cell leukemia, codes for a protein with a helix-loop-helix DNA binding motif

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7 January 2021

LAZ3, a novel zinc-finger encoding gene, is disrupted by recurring chromosome 3q27 translocations in human lymphomas

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7 January 2021

Alterations of a zinc finger-encoding gene, BCL-6, in diffuse large-cell lymphoma

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7 January 2021

B cell lymphoma-associated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-kappa B p50

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7 January 2021

The candidate proto-oncogene bcl-3 is related to genes implicated in cell lineage determination and cell cycle control

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7 January 2021

Candidate proto-oncogene bcl-3 encodes a subunit-specific inhibitor of transcription factor NF-kappa B

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7 January 2021

The proto-oncogene bcl-3 encodes an I kappa B protein

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7 January 2021

TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

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7 January 2021

The LCK gene is involved in the t(1;7)(p34;q34) in the T-cell acute lymphoblastic leukemia derived cell line, HSB-2.

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7 January 2021

Chromosomal translocations joining LCK and TCRB loci in human T cell leukemia

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7 January 2021

Fusion of an immunoglobulin variable gene and a T cell receptor constant gene in the chromosome 14 inversion associated with T cell tumors

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7 January 2021

A chromosome 14 inversion in a T-cell lymphoma is caused by site-specific recombination between immunoglobulin and T-cell receptor loci

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7 January 2021

A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia

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7 January 2021

Genes on chromosomes 4, 9, and 19 involved in 11q23 abnormalities in acute leukemia share sequence homology and/or common motifs

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7 January 2021

Leucine-zipper dimerization motif encoded by the AF17 gene fused to ALL-1 (MLL) in acute leukemia

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7 January 2021

Generation of the AML1-EVI-1 fusion gene in the t(3;21)(q26;q22) causes blastic crisis in chronic myelocytic leukemia

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7 January 2021

The 3;21 translocation in myelodysplasia results in a fusion transcript between the AML1 gene and the gene for EAP, a highly conserved protein associated with the Epstein-Barr virus small RNA EBER 1

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7 January 2021

The translocation (6;9), associated with a specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-specific dek-can mRNA

1 reference

7 January 2021

Characterization of the translocation breakpoint sequences of two DEK-CAN fusion genes present in t(6;9) acute myeloid leukemia and a SET-CAN fusion gene found in a case of acute undifferentiated leukemia

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7 January 2021

Fusion between transcription factor CBF beta/PEBP2 beta and a myosin heavy chain in acute myeloid leukemia

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7 January 2021