Protein kinase Cθ: the pleiotropic T-cell signalling intermediate. (Q54309549)

27 May 2018

title

Protein kinase Cθ: the pleiotropic T-cell signalling intermediate. (English)

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27 May 2018

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Katarzyna Wachowicz

1

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27 May 2018

Gottfried Baier

series ordinal

2

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27 May 2018

publication date

1 December 2014

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27 May 2018

Biochemical Society Transactions

published in

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27 May 2018

volume

42

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27 May 2018

issue

6

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27 May 2018

page(s)

1512-1518

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27 May 2018

Protein kinase C: poised to signal

cites work

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

In and out of the bull's eye: protein kinase Cs in the immunological synapse

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

PKC-theta-mediated signal delivery from the TCR/CD28 surface receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

PKCtheta signals activation versus tolerance in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

A motif in the V3 domain of the kinase PKC-θ determines its localization in the immunological synapse and functions in T cells via association with CD28

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

Protein kinase C theta affects Ca2+ mobilization and NFAT cell activation in primary mouse T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

The nuclear orphan receptor NR2F6 suppresses lymphocyte activation and T helper 17-dependent autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

PKC-theta modulates the strength of T cell responses by targeting Cbl-b for ubiquitination and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

Loss of protein kinase C theta, Bcl10, or Malt1 selectively impairs proliferation and NF-kappa B activation in the CD4+ T cell subset.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

T-cell fate and function: PKC-theta and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

Protein kinase C theta is critical for the development of in vivo T helper (Th)2 cell but not Th1 cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

Protective Toxoplasma gondii-specific T-cell responses require T-cell-specific expression of protein kinase C-theta

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

Innate signals compensate for the absence of PKC-{theta} during in vivo CD8(+) T cell effector and memory responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

Protein kinase C-theta is required for development of experimental cerebral malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

PKC theta ablation improves healing in a mouse model of muscular dystrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

A critical role for protein kinase C-theta-mediated T cell survival in cardiac allograft rejection

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

PKC theta cooperates with PKC alpha in alloimmune responses of T cells in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

PKCtheta is required for alloreactivity and GVHD but not for immune responses toward leukemia and infection in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

Pharmacologic inhibition of PKCα and PKCθ prevents GVHD while preserving GVL activity in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

NOTCH1 promotes T cell leukemia-initiating activity by RUNX-mediated regulation of PKC-θ and reactive oxygen species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

Protein kinase C theta plays a fundamental role in different types of chronic colitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

PKC-theta-deficient mice are protected from Th1-dependent antigen-induced arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

Protein kinase Ctheta controls Th1 cells in experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

Resistance to experimental autoimmune encephalomyelitis and impaired IL-17 production in protein kinase C theta-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

Protein kinase C-θ promotes Th17 differentiation via upregulation of Stat3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

Protein kinase C θ regulates the phenotype of murine CD4+ Th17 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

Differential invasion of Trypanosoma brucei brucei and lymphocytes into the brain of C57BL/6 and 129Sv/Ev mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

PKC inhibitors: potential in T cell-dependent immune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

Differential regulation of central nervous system autoimmunity by T(H)1 and T(H)17 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

Cross-regulation of signaling pathways by interferon-gamma: implications for immune responses and autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

Th17 cells promote pancreatic inflammation but only induce diabetes efficiently in lymphopenic hosts after conversion into Th1 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

Essentials of Th17 cell commitment and plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

Genetic proof for the transient nature of the Th17 phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

Early signaling events that underlie fate decisions of naive CD4(+) T cells toward distinct T-helper cell subsets

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

Low-strength T-cell activation promotes Th17 responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

Low dose CP-690,550 (tofacitinib), a pan-JAK inhibitor, accelerates the onset of experimental autoimmune encephalomyelitis by potentiating Th17 differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

Differential activation of ERK, p38, and JNK required for Th1 and Th2 deviation in myelin-reactive T cells induced by altered peptide ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

The kinase PKCα selectively upregulates interleukin-17A during Th17 cell immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

Differential requirement of PKC-theta in the development and function of natural regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

Protein kinase C-θ inhibits inducible regulatory T cell differentiation via an AKT-Foxo1/3a-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

Protein kinase C-theta mediates negative feedback on regulatory T cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

Protein Kinase C-θ (PKC-θ) in Natural Killer Cell Function and Anti-Tumor Immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

TNFa alter cholesterol metabolism in human macrophages via PKC-θ-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140179

21 January 2018

Identifiers

DOI

10.1042/BST20140179

1 reference

27 May 2018

release_6n3j7var2radjmki3wlan6xuom

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/6n3j7var2radjmki3wlan6xuom

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

25399562

1 reference

27 May 2018