Protein kinase C theta is critical for the development of in vivo T helper (Th)2 cell but not Th1 cell responses (Q28594762)

Journal of Experimental Medicine

GOA release 2020-03-11

Manfred Kopf

5

0 references

Dan Littman

series ordinal

4

object named as

Dan R. Littman

1 reference

31 January 2017

Benjamin J. Marsland

1

1 reference

31 January 2017

Timothy J. Soos

series ordinal

2

1 reference

31 January 2017

Gerald Späth

series ordinal

3

1 reference

31 January 2017

language of work or name

English

0 references

publication date

19 July 2004

1 reference

31 January 2017

1 reference

31 January 2017

200

1 reference

31 January 2017

181–189

1 reference

31 January 2017

2

1 reference

31 January 2017

Protein kinase C theta affects Ca2+ mobilization and NFAT cell activation in primary mouse T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212016

Complex formation and cooperation of protein kinase C theta and Akt1/protein kinase B alpha in the NF-kappa B transactivation cascade in Jurkat T cells

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212016

The immunological synapse: a molecular machine controlling T cell activation

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212016

Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212016

Three-dimensional segregation of supramolecular activation clusters in T cells

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212016

Molecular cloning and characterization of PKC theta, a novel member of the protein kinase C (PKC) gene family expressed predominantly in hematopoietic cells

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212016

Purified interleukin 5 supports the terminal differentiation and proliferation of murine eosinophilic precursors

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212016

The pleckstrin homology domain of Bruton tyrosine kinase interacts with protein kinase C

17 March 2017

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20032229

Interleukin 2 plays a central role in Th2 differentiation.

28 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212016

The PKC gene module: molecular biosystematics to resolve its T cell functions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212016

CD28 plays a critical role in the segregation of PKC theta within the immunologic synapse

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212016

The immunological synapse.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212016

Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212016

Protein kinase Ctheta: a new essential superstar on the T-cell stage

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212016

Essential role of nuclear factor kappaB in the induction of eosinophilia in allergic airway inflammation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212016

Induction of interleukin-12 p40 transcript by CD40 ligation via activation of nuclear factor-kappaB.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212016

The transcription factor NF-ATc1 regulates lymphocyte proliferation and Th2 cytokine production

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212016

The regulation of immunity to Leishmania major

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212016

Interleukin 4 causes isotype switching to IgE in T cell-stimulated clonal B cell cultures

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212016

Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212016

Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212016

Eosinophilia in transgenic mice expressing interleukin 5.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212016

Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212016

Cross-linking Fc receptors stimulate splenic non-B, non-T cells to secrete interleukin 4 and other lymphokines

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212016

A novel functional interaction between Vav and PKCtheta is required for TCR-induced T cell activation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212016

Regulation of protein kinase Ctheta function during T cell activation by Lck-mediated tyrosine phosphorylation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212016

Impaired NFATc translocation and failure of Th2 development in Itk-deficient CD4+ T cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212016

A limiting dilution assay for quantifying Leishmania major in tissues of infected mice

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212016

Murine cutaneous leishmaniasis: resistance correlates with the capacity to generate interferon-gamma in response to Leishmania antigens in vitro

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212016

Antigen-induced translocation of PKC-theta to membrane rafts is required for T cell activation

3 June 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20032229

NFATc2 and NFATc3 regulate T(H)2 differentiation and modulate TCR-responsiveness of naïve T(H)cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20032229

Vav1-deficient mice are resistant to MOG-induced experimental autoimmune encephalomyelitis due to impaired antigen priming.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20032229

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20032229

The antigen dose determines T helper subset development by regulation of CD40 ligand

21 January 2018

1 reference

12 December 2020

Frequencies of IL-2- and IL-4-secreting T cells in naive and antigen-stimulated lymphocyte populations

1 reference

12 December 2020

IL-2 is necessary for the progression of leishmaniasis in susceptible murine hosts

1 reference

12 December 2020

Interaction of NF-kappaB and NFAT with the interferon-gamma promoter

1 reference

12 December 2020

A critical role for NF-kappa B in GATA3 expression and TH2 differentiation in allergic airway inflammation

1 reference

12 December 2020

Critical role for IL-13 in the development of allergen-induced airway hyperreactivity

1 reference

12 December 2020

Differential Requirement for NF- B Family Members in Control of Helminth Infection and Intestinal Inflammation

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20032229

1 reference

1832282

1832282

1 reference

1 reference

1 reference