Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer. (Q54209542)

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26 March 2020

title

Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer (English)

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26 March 2020

4

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Anita Sarkar

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26 March 2020

Jesper Pallesen

7

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26 March 2020

Max Crispin

12

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26 March 2020

Ian A Wilson

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26 March 2020

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Andrew B Ward

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26 March 2020

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Richard T Wyatt

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26 March 2020

author name string

Shridhar Bale

2

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26 March 2020

Anna-Janina Behrens

3

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26 March 2020

Shailendra Kumar Sharma

5

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26 March 2020

Natalia de Val

6

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26 March 2020

Adriana Irimia

8

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26 March 2020

Devan C Diwanji

9

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26 March 2020

Robyn L Stanfield

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language of work or name

English

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publication date

16 May 2018

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26 March 2020

published in

Nature Communications

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26 March 2020

volume

9

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26 March 2020

page(s)

1956

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26 March 2020

issue

1

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Creative Commons Attribution 4.0 International

26 March 2020

copyright license

start time

16 May 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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exact match

https://scigraph.springernature.com/pub.10.1038/s41467-018-04272-y

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Broadly Neutralizing Antibody Responses in a Large Longitudinal Sub-Saharan HIV Primary Infection Cohort

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Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.

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Influences on the Design and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers

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26 May 2018

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26 May 2018

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Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer

26 May 2018

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Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer

26 May 2018

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Cleavage strongly influences whether soluble HIV-1 envelope glycoprotein trimers adopt a native-like conformation

26 May 2018

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A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies

26 May 2018

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Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies

26 May 2018

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Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization

26 May 2018

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Broadly Neutralizing Antibody PGT121 Allosterically Modulates CD4 Binding via Recognition of the HIV-1 gp120 V3 Base and Multiple Surrounding Glycans

26 May 2018

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Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM.

26 May 2018

1 reference

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Prevention of overfitting in cryo-EM structure determination

26 May 2018

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Structural basis for germ-line gene usage of a potent class of antibodies targeting the CD4-binding site of HIV-1 gp120.

26 May 2018

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A Bayesian view on cryo-EM structure determination.

26 May 2018

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Progress in the rational design of an AIDS vaccine

26 May 2018

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Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

26 May 2018

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HIV-1 envelope glycoprotein biosynthesis, trafficking, and incorporation

26 May 2018

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Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01

26 May 2018

1 reference

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Structure-function relationships of HIV-1 envelope sequence-variable regions refocus vaccine design

26 May 2018

1 reference

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PHENIX: a comprehensive Python-based system for macromolecular structure solution

26 May 2018

1 reference

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MolProbity: all-atom structure validation for macromolecular crystallography

26 May 2018

1 reference

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FREAD revisited: Accurate loop structure prediction using a database search algorithm.

26 May 2018

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26 May 2018

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Structure, Receptor Binding, and Antigenicity of Influenza Virus Hemagglutinins from the 1957 H2N2 Pandemic

26 May 2018

1 reference

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Phasercrystallographic software

26 May 2018

1 reference

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High-throughput thermal scanning: a general, rapid dye-binding thermal shift screen for protein engineering

26 May 2018

1 reference

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Appion: an integrated, database-driven pipeline to facilitate EM image processing

26 May 2018

1 reference

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Biochemical and biophysical comparison of cleaved and uncleaved soluble, trimeric HIV-1 envelope glycoproteins

26 May 2018

1 reference

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The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability

26 May 2018

1 reference

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GLYCAM06: a generalizable biomolecular force field. Carbohydrates

26 May 2018

1 reference

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Comparison of multiple Amber force fields and development of improved protein backbone parameters

26 May 2018

1 reference

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Automated molecular microscopy: the new Leginon system

26 May 2018

1 reference

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Coot: model-building tools for molecular graphics

26 May 2018

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pdb-care (PDB carbohydrate residue check): a program to support annotation of complex carbohydrate structures in PDB files

26 May 2018

1 reference

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Topology representing network enables highly accurate classification of protein images taken by cryo electron-microscope without masking.

26 May 2018

1 reference

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Accurate determination of local defocus and specimen tilt in electron microscopy

26 May 2018

1 reference

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Stabilization of the soluble, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1.

26 May 2018

1 reference

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A recombinant human immunodeficiency virus type 1 envelope glycoprotein complex stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits is an antigenic mimic of the trimeric virion-associated structure

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5955915

The glycosylation of human immunodeficiency virus type 1 transmembrane glycoprotein (gp41) is important for the efficient intracellular transport of the envelope precursor gp160.

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5955915

Neutralization of the AIDS retrovirus by antibodies to a recombinant envelope glycoprotein

26 May 2018

1 reference

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Endoproteolytic cleavage of gp160 is required for the activation of human immunodeficiency virus

26 May 2018

1 reference

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Folding, interaction with GRP78-BiP, assembly, and transport of the human immunodeficiency virus type 1 envelope protein

26 May 2018

1 reference

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Privateer: software for the conformational validation of carbohydrate structures.

26 May 2018

1 reference

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Development of a single column method for the separation of lipid- and protein-derived oligosaccharides

13 August 2018

1 reference

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Antibody elbow angles are influenced by their light chain class.

13 August 2018

1 reference

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H1 and H7 influenza haemagglutinin structures extend a structural classification of haemagglutinin subtypes.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5955915

Comparison of simple potential functions for simulating liquid water

13 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FS41467-018-04272-Y

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/S41467-018-04272-Y

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29769533%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29769533%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

1 reference