HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers (Q28647225)

Jeong Hyun Lee

13

0 references

Marit J. van Gils

Marit J van Gils

2

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Cassandra Simonich

Cassandra Simonich

9

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Ian Andrew Wilson

31

Ian A Wilson

0 references

Julie Overbaugh

32

Julie Overbaugh

0 references

David C. Montefiori

35

David C Montefiori

0 references

Leslie Goo

10

Leslie Goo

0 references

William R Schief

30

William R Schief

0 references

Dennis R. Burton

33

Dennis R Burton

0 references

Andrew B Ward

34

Andrew B Ward

0 references

Rogier W Sanders

1

Rogier W Sanders

0 references

John P. Moore

37

John P Moore

0 references

Gabriel Ozorowski

7

Gabriel Ozorowski

0 references

Per Johan Klasse

28

Per Johan Klasse

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Michael S Seaman

25

Michael S Seaman

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Celia C LaBranche

29

Celia LaBranche

0 references

Devin Sok

4

Devin Sok

0 references

Brian Moldt

17

Brian Moldt

0 references

Albert Cupo

8

Albert Cupo

0 references

Ronald Derking

3

Ronald Derking

0 references

Thomas J Ketas

5

Thomas J Ketas

0 references

Pavel Pugach

14

Pavel Pugach

0 references

Gargi Debnath

16

Gargi Debnath

0 references

Mariëlle J. van Breemen

18

Mariëlle J van Breemen

0 references

Max Medina-Ramírez

20

Max Medina-Ramírez

0 references

Wayne C Koff

22

Wayne C Koff

0 references

Eva G Rakasz

24

Eva G Rakasz

0 references

Miklos Guttman

26

Miklos Guttman

0 references

Kelly K Lee

27

Kelly K Lee

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author name string

Judith A Burger

6

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Heather Arendt

11

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Helen J Kim

12

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Melissa Williams

15

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Gözde Isik

19

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Jaap Willem Back

21

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Hansi Dean

Structural Constraints Determine the Glycosylation of HIV-1 Envelope Trimers

36

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language of work or name

English

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publication date

10 July 2015

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published in

Science

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volume

349

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page(s)

aac4223

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issue

6244

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cites work

1 reference

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Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers

17 March 2017

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Development of broadly neutralizing antibodies from autologous neutralizing antibody responses in HIV infection

17 March 2017

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Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

17 March 2017

1 reference

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Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign

17 March 2017

1 reference

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Structural insights on the role of antibodies in HIV-1 vaccine and therapy

17 March 2017

1 reference

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Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer

17 March 2017

1 reference

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Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer

17 March 2017

1 reference

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A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120

17 March 2017

1 reference

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Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

17 March 2017

1 reference

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Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors

17 March 2017

1 reference

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Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

17 March 2017

1 reference

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Broad neutralization coverage of HIV by multiple highly potent antibodies

17 March 2017

1 reference

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Appion: an integrated, database-driven pipeline to facilitate EM image processing

7 April 2017

1 reference

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Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

HIV antibodies. Antigen modification regulates competition of broad and narrow neutralizing HIV antibodies.

3 June 2018

1 reference

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Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Structure and immune recognition of trimeric pre-fusion HIV-1 Env.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Envelope variants circulating as initial neutralization breadth developed in two HIV-infected subjects stimulate multiclade neutralizing antibodies in rabbits.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Glycosylation and disulfide bond analysis of transiently and stably expressed clade C HIV-1 gp140 trimers in 293T cells identifies disulfide heterogeneity present in both proteins and differences in O-linked glycosylation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

CD4-induced activation in a soluble HIV-1 Env trimer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Differential binding of neutralizing and non-neutralizing antibodies to native-like soluble HIV-1 Env trimers, uncleaved Env proteins, and monomeric subunits

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Early development of broadly neutralizing antibodies in HIV-1-infected infants

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Boosting of HIV-1 neutralizing antibody responses by a distally related retroviral envelope protein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Prevalence of broadly neutralizing antibody responses during chronic HIV-1 infection

3 June 2018

1 reference

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Global panel of HIV-1 Env reference strains for standardized assessments of vaccine-elicited neutralizing antibodies

3 June 2018

1 reference

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Cleavage strongly influences whether soluble HIV-1 envelope glycoprotein trimers adopt a native-like conformation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

A functional interaction between gp41 and gp120 is observed for monomeric but not oligomeric, uncleaved HIV-1 Env gp140.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Prime-boost interval matters: a randomized phase 1 study to identify the minimum interval necessary to observe the H5 DNA influenza vaccine priming effect

3 June 2018

1 reference

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Identification of an HIV-1 clade A envelope that exhibits broad antigenicity and neutralization sensitivity and elicits antibodies targeting three distinct epitopes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Broadly neutralizing antibodies against HIV-1: templates for a vaccine

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Partial enzymatic deglycosylation preserves the structure of cleaved recombinant HIV-1 envelope glycoprotein trimers

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

The development of CD4 binding site antibodies during HIV-1 infection

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

B-cell-lineage immunogen design in vaccine development with HIV-1 as a case study

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Subtle alteration of residues including N-linked glycans in V2 loop modulate HIV-1 neutralization by PG9 and PG16 monoclonal antibodies

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Targeting HIV-1 envelope glycoprotein trimers to B cells by using APRIL improves antibody responses

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Env-glycoprotein heterogeneity as a source of apparent synergy and enhanced cooperativity in inhibition of HIV-1 infection by neutralizing antibodies and entry inhibitors

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Helical peptide arrays for lead identification and interaction site mapping.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Analysis of the disulfide bond arrangement of the HIV-1 envelope protein CON-S gp140 ΔCFI shows variability in the V1 and V2 regions

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Lack of complex N-glycans on HIV-1 envelope glycoproteins preserves protein conformation and entry function

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Breadth of neutralizing antibodies elicited by stable, homogeneous clade A and clade C HIV-1 gp140 envelope trimers in guinea pigs

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Comparative immunogenicity of subtype a Human Immunodeficiency Virus type 1 envelope exhibiting differential exposure of conserved neutralization epitopes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Tiered categorization of a diverse panel of HIV-1 Env pseudoviruses for assessment of neutralizing antibodies

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Structural and immunogenicity studies of a cleaved, stabilized envelope trimer derived from subtype A HIV-1

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Human immunodeficiency virus type 1 elite neutralizers: individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay together with an analytical selection algorithm

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Development of prophylactic and therapeutic vaccines using the ISCOMATRIX adjuvant

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

DoG Picker and TiltPicker: software tools to facilitate particle selection in single particle electron microscopy

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Measuring HIV neutralization in a luciferase reporter gene assay

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Genetic and neutralization properties of subtype C human immunodeficiency virus type 1 molecular env clones from acute and early heterosexually acquired infections in Southern Africa

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Neutralization escape variants of human immunodeficiency virus type 1 are transmitted from mother to infant

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Biochemical and immunogenic characterization of soluble human immunodeficiency virus type 1 envelope glycoprotein trimers expressed by semliki forest virus

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Topology representing network enables highly accurate classification of protein images taken by cryo electron-microscope without masking.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Probing the structure of the human immunodeficiency virus surface glycoprotein gp120 with a panel of monoclonal antibodies

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498988

Analysis of the neutralizing antibody response elicited in rabbits by repeated inoculation with trimeric HIV-1 envelope glycoproteins.

3 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC4223

A comparative immunogenicity study in rabbits of disulfide-stabilized, proteolytically cleaved, soluble trimeric human immunodeficiency virus type 1 gp140, trimeric cleavage-defective gp140 and monomeric gp120.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC4223

21 January 2018

Identifiers

DOI

10.1126/SCIENCE.AAC4223

1 reference

190536

190536

1 reference

1 reference

1 reference