FOXM1 is a critical driver of lung fibroblast activation and fibrogenesis. (Q53686964)

17 May 2018

title

FOXM1 is a critical driver of lung fibroblast activation and fibrogenesis. (English)

1 reference

17 May 2018

6

Marc Peters-Golden

1 reference

17 May 2018

author name string

Loka R Penke

1

1 reference

17 May 2018

Jennifer M Speth

2

1 reference

17 May 2018

Vijaya L Dommeti

3

1 reference

17 May 2018

Eric S White

4

1 reference

17 May 2018

Ingrid L Bergin

5

1 reference

17 May 2018

language of work or name

English

0 references

publication date

7 May 2018

1 reference

17 May 2018

Journal of Clinical Investigation

published in

1 reference

17 May 2018

Fibroblast-specific inhibition of TGF-β1 signaling attenuates lung and tumor fibrosis

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4 October 2018

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4 October 2018

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4 October 2018

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4 October 2018

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4 October 2018

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4 October 2018

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4 October 2018

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4 October 2018

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4 October 2018

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4 October 2018

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4 October 2018

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4 October 2018

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Prostaglandin E(2) induces fibroblast apoptosis by modulating multiple survival pathways.

4 October 2018

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4 October 2018

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Thiazole antibiotics target FoxM1 and induce apoptosis in human cancer cells

4 October 2018

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A novel mode of FoxM1 regulation: positive auto-regulatory loop

4 October 2018

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Critical role of serum response factor in pulmonary myofibroblast differentiation induced by TGF-beta

4 October 2018

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4 October 2018

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Isoform B of myosin II heavy chain mediates actomyosin contractility during TNFalpha-induced apoptosis

4 October 2018

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4 October 2018

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4 October 2018

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4 October 2018

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An N-terminal inhibitory domain modulates activity of FoxM1 during cell cycle

4 October 2018

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4 October 2018

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4 October 2018

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The FoxM1 transcription factor is required to maintain pancreatic beta-cell mass.

4 October 2018

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Forkhead box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase

4 October 2018

1 reference

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Bleomycin-induced E prostanoid receptor changes alter fibroblast responses to prostaglandin E2.

4 October 2018

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Altered expression of membrane-bound and soluble CD95/Fas contributes to the resistance of fibrotic lung fibroblasts to FasL induced apoptosis

4 October 2018

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Modulation of prosurvival signaling in fibroblasts by a protein kinase inhibitor protects against fibrotic tissue injury.

4 October 2018

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4 October 2018

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The mouse Forkhead Box m1 transcription factor is essential for hepatoblast mitosis and development of intrahepatic bile ducts and vessels during liver morphogenesis

4 October 2018

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Severity of lung injury in cyclooxygenase-2-deficient mice is dependent on reduced prostaglandin E(2) production.

4 October 2018

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Comparison of the morphological and biochemical changes in normal human lung fibroblasts and fibroblasts derived from lungs of patients with idiopathic pulmonary fibrosis during FasL-induced apoptosis

4 October 2018

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Prostaglandin E2 inhibits fibroblast to myofibroblast transition via E. prostanoid receptor 2 signaling and cyclic adenosine monophosphate elevation.

4 October 2018

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Prostaglandin E2 synthesis and suppression of fibroblast proliferation by alveolar epithelial cells is cyclooxygenase-2-dependent.

4 October 2018

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4 October 2018

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IL-7 inhibits fibroblast TGF-beta production and signaling in pulmonary fibrosis

4 October 2018

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4 October 2018

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4 October 2018

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Cultured lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis have a diminished capacity to synthesize prostaglandin E2 and to express cyclooxygenase-2.

4 October 2018

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4 October 2018

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p67SRF is a constitutive nuclear protein implicated in the modulation of genes required throughout the G1 period

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Epithelial cell-derived transforming growth factor-beta in bleomycin-induced pulmonary injury

4 October 2018

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12 December 2020

GM-CSF Regulates Bleomycin-Induced Pulmonary Fibrosis Via a Prostaglandin-Dependent Mechanism

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12 December 2020

Idiopathic pulmonary fibrosis: a disease with similarities and links to cancer biology

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12 December 2020

Nintedanib and pirfenidone. New antifibrotic treatments indicated for idiopathic pulmonary fibrosis offer hopes and raises questions

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12 December 2020

Identifiers

DOI

10.1172/JCI87631

1 reference

17 May 2018

0 references

1 reference

17 May 2018