FoxO3a (Forkhead Box O3a) deficiency protects Idiopathic Pulmonary Fibrosis (IPF) fibroblasts from type I polymerized collagen matrix-induced apoptosis via caveolin-1 (cav-1) and Fas. (Q34666156)

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English	FoxO3a (Forkhead Box O3a) deficiency protects Idiopathic Pulmonary Fibrosis (IPF) fibroblasts from type I polymerized collagen matrix-induced apoptosis via caveolin-1 (cav-1) and Fas.	scientific article

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scholarly article

1 reference

Europe PubMed Central

3 August 2017

FoxO3a (Forkhead Box O3a) deficiency protects Idiopathic Pulmonary Fibrosis (IPF) fibroblasts from type I polymerized collagen matrix-induced apoptosis via caveolin-1 (cav-1) and Fas. (English)

1 reference

Europe PubMed Central

3 August 2017

pulmonary fibrosis

1 reference

based on heuristic

inferred from title

idiopathic pulmonary fibrosis

1 reference

based on heuristic

inferred from title

author name string

Richard Seonghun Nho

1

1 reference

Europe PubMed Central

3 August 2017

Mark Peterson

2

1 reference

Europe PubMed Central

3 August 2017

Polla Hergert

3

1 reference

Europe PubMed Central

3 August 2017

Craig A Henke

4

1 reference

Europe PubMed Central

3 August 2017

language of work or name

0 references

publication date

8 April 2013

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

8

1 reference

Europe PubMed Central

3 August 2017

e61017

1 reference

Europe PubMed Central

3 August 2017

4

1 reference

Europe PubMed Central

3 August 2017

copyright license

Creative Commons Attribution 4.0 International

8 April 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

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1 reference

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Pathological alteration of FoxO3a activity promotes idiopathic pulmonary fibrosis fibroblast proliferation on type i collagen matrix

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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beta1-Integrin-collagen interaction suppresses FoxO3a by the coordination of Akt and PP2A

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Endothelin-1 and transforming growth factor-beta1 independently induce fibroblast resistance to apoptosis via AKT activation

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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PI3K/Akt/FOXO3a pathway contributes to thrombopoietin-induced proliferation of primary megakaryocytes in vitro and in vivo via modulation of p27(Kip1).

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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PTEN regulates fibroblast elimination during collagen matrix contraction

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Direct control of caveolin-1 expression by FOXO transcription factors

1 reference

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1 reference

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1 reference

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

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Myofibroblasts. I. Paracrine cells important in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

7 July 2018

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

7 July 2018

Idiopathic pulmonary fibrosis: current concepts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

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The roles of the myofibroblast in idiopathic pulmonary fibrosis. Ultrastructural and immunohistochemical features of sites of active extracellular matrix synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

7 July 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

7 July 2018

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1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061017

21 January 2018

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1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061017

21 January 2018

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1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061017

21 January 2018

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1 reference

https://pubmed.ncbi.nlm.nih.gov/23580232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/23580232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/23580232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1371/JOURNAL.PONE.0061017

1 reference

Europe PubMed Central

3 August 2017

2013PLoSO...861017N

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1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

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