Prostaglandin E2 inhibits α-smooth muscle actin transcription during myofibroblast differentiation via distinct mechanisms of modulation of serum response factor and myocardin-related transcription factor-A (Q33761334)

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English	Prostaglandin E2 inhibits α-smooth muscle actin transcription during myofibroblast differentiation via distinct mechanisms of modulation of serum response factor and myocardin-related transcription factor-A	scientific article

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17 March 2020

Prostaglandin E2 inhibits α-smooth muscle actin transcription during myofibroblast differentiation via distinct mechanisms of modulation of serum response factor and myocardin-related transcription factor-A (English)

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17 March 2020

prostaglandin E2

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Loka Raghu Kumar Penke

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17 March 2020

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17 March 2020

Marc Peters-Golden

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Marc Peters-Golden

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17 March 2020

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Steven K Huang

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5 May 2014

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17 March 2020

Journal of Biological Chemistry

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17 March 2020

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17 March 2020

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17 March 2020

17151-17162

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17 March 2020

Reversal of myofibroblast differentiation by prostaglandin E(2).

1 reference

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21 June 2018

Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis

1 reference

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21 June 2018

Matrices of physiologic stiffness potently inactivate idiopathic pulmonary fibrosis fibroblasts

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21 June 2018

The myofibroblast matrix: implications for tissue repair and fibrosis.

1 reference

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21 June 2018

New cellular and molecular mechanisms of lung injury and fibrosis in idiopathic pulmonary fibrosis

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21 June 2018

Molecular and cellular mechanisms of pulmonary fibrosis

1 reference

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21 June 2018

PTEN directly activates the actin depolymerization factor cofilin-1 during PGE2-mediated inhibition of phagocytosis of fungi

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21 June 2018

Prostaglandin E2 as an inhibitory modulator of fibrogenesis in human lung allografts

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21 June 2018

Airway remodeling in murine asthma correlates with a defect in PGE2 synthesis by lung fibroblasts

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21 June 2018

Delayed stress fiber formation mediates pulmonary myofibroblast differentiation in response to TGF-β.

1 reference

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21 June 2018

Plasmin overcomes resistance to prostaglandin E2 in fibrotic lung fibroblasts by reorganizing protein kinase A signaling

1 reference

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21 June 2018

Myocardin-related transcription factors A and B are key regulators of TGF-β1-induced fibroblast to myofibroblast differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059156

21 June 2018

Hypermethylation of PTGER2 confers prostaglandin E2 resistance in fibrotic fibroblasts from humans and mice

1 reference

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21 June 2018

Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059156

21 June 2018

Diminished prostaglandin E2 contributes to the apoptosis paradox in idiopathic pulmonary fibrosis

1 reference

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21 June 2018

Role of HuR and p38MAPK in ultraviolet B-induced post-transcriptional regulation of COX-2 expression in the human keratinocyte cell line HaCaT.

1 reference

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21 June 2018

Phosphatase and tensin homologue on chromosome 10 (PTEN) directs prostaglandin E2-mediated fibroblast responses via regulation of E prostanoid 2 receptor expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059156

21 June 2018

Eicosanoid lipid mediators in fibrotic lung diseases: ready for prime time?

1 reference

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21 June 2018

Myofibroblast contraction activates latent TGF-beta1 from the extracellular matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059156

21 June 2018

Variable prostaglandin E2 resistance in fibroblasts from patients with usual interstitial pneumonia

1 reference

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21 June 2018

PGE(2) inhibition of TGF-beta1-induced myofibroblast differentiation is Smad-independent but involves cell shape and adhesion-dependent signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059156

21 June 2018

Myocardin-related transcription factors: critical coactivators regulating cardiovascular development and adaptation.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059156

21 June 2018

Actin' together: serum response factor, its cofactors and the link to signal transduction

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059156

21 June 2018

Cyclic AMP inhibits p38 activation via CREB-induced dynein light chain.

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21 June 2018

Transforming growth factor-beta1-induced expression of smooth muscle marker genes involves activation of PKN and p38 MAPK.

1 reference

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21 June 2018

Selective activation of mitogen-activated protein (MAP) kinase kinase 3 and p38alpha MAP kinase is essential for cyclic AMP-dependent UCP1 expression in adipocytes

1 reference

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21 June 2018

Prostaglandin E(2) inhibits fibroblast migration by E-prostanoid 2 receptor-mediated increase in PTEN activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059156

21 June 2018

TGF-beta signaling and the fibrotic response

1 reference

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21 June 2018

p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene

1 reference

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21 June 2018

Megakaryoblastic leukemia factor-1 transduces cytoskeletal signals and induces smooth muscle cell differentiation from undifferentiated embryonic stem cells

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21 June 2018

Downregulation of p38 kinase pathway by cAMP response element-binding protein protects HL-60 cells from iron chelator-induced apoptosis

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21 June 2018

Actin dynamics control SRF activity by regulation of its coactivator MAL

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21 June 2018

Myofibroblasts and mechano-regulation of connective tissue remodelling

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21 June 2018

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21 June 2018

Catalytic activation of mitogen-activated protein (MAP) kinase phosphatase-1 by binding to p38 MAP kinase: critical role of the p38 C-terminal domain in its negative regulation

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21 June 2018

Similarities and differences in smooth muscle alpha-actin induction by TGF-beta in smooth muscle versus non-smooth muscle cells

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21 June 2018

Signal-regulated activation of serum response factor is mediated by changes in actin dynamics

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21 June 2018

Regulation of smooth muscle alpha-actin expression in vivo is dependent on CArG elements within the 5' and first intron promoter regions

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21 June 2018

A serum response factor-dependent transcriptional regulatory program identifies distinct smooth muscle cell sublineages

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21 June 2018

Apoptosis during wound healing, fibrocontractive diseases and vascular wall injury

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21 June 2018

Cultured lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis have a diminished capacity to synthesize prostaglandin E2 and to express cyclooxygenase-2.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059156

21 June 2018

Catalytic activation of mitogen-activated protein (MAP) kinase phosphatase-1 by binding to p38 MAP kinase: critical role of the p38 C-terminal domain in its negative regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.558130

21 January 2018

MKL1 mediates TGF-beta1-induced alpha-smooth muscle actin expression in human renal epithelial cells

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21 January 2018

Critical role of serum response factor in pulmonary myofibroblast differentiation induced by TGF-beta

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21 January 2018

Prostaglandin E2 inhibits fibroblast to myofibroblast transition via E. prostanoid receptor 2 signaling and cyclic adenosine monophosphate elevation.

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21 January 2018

Contractility as a prerequisite for TGF-beta-induced myofibroblast transdifferentiation in human tenon fibroblasts.

1 reference

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21 January 2018

Involvement of serum response factor isoforms in myofibroblast differentiation during bleomycin-induced lung injury

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21 January 2018

Myofibroblast differentiation by transforming growth factor-beta1 is dependent on cell adhesion and integrin signaling via focal adhesion kinase.

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21 January 2018

Bleomycin-induced E prostanoid receptor changes alter fibroblast responses to prostaglandin E2.

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21 January 2018

GM-CSF Regulates Bleomycin-Induced Pulmonary Fibrosis Via a Prostaglandin-Dependent Mechanism

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12 December 2020

based on heuristic

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p38 inhibitors prevent TGF-beta-induced myofibroblast transdifferentiation in human tenon fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/24802754

12 December 2020

based on heuristic

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The intrinsic prostaglandin E2-EP4 system of the renal tubular epithelium limits the development of tubulointerstitial fibrosis in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/24802754

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1074/JBC.M114.558130

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17 March 2020

1 reference

Europe PubMed Central

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17 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24802754%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

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