Expression of centrosome-associated gene products is linked to tetraploidization in mantle cell lymphoma. (Q53576365)

15 May 2018

title

Expression of centrosome-associated gene products is linked to tetraploidization in mantle cell lymphoma. (English)

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11

Peter Lichter

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Hans Konrad Müller-Hermelink

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object named as

Hans Konrad Müller-Hermelink

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Andreas Rosenwald

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object named as

Andreas Rosenwald

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15 May 2018

author name string

Kai Neben

1

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15 May 2018

German Ott

2

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Silja Schweizer

3

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Jörg Kalla

4

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Björn Tews

5

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Tiemo Katzenberger

6

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Meinhard Hahn

7

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Anthony D Ho

9

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Alwin Krämer

12

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language of work or name

English

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publication date

1 April 2007

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International Journal of Cancer

published in

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volume

120

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page(s)

1669-1677

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issue

8

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Cell cycle control and cancer

cites work

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Pathways of spindle assembly

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How cells get the right chromosomes

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Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A.

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Requirement of Cdk2-cyclin E activity for repeated centrosome reproduction in Xenopus egg extracts

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Cyclin-dependent kinase control of centrosome duplication

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Centrosome aberrations in hematological malignancies

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Genetic instability in colorectal cancers

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Centrosome hyperamplification in human cancer: chromosome instability induced by p53 mutation and/or Mdm2 overexpression.

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Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

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Cell biology. Do centrosome abnormalities lead to cancer?

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Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells

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DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

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Centrosome amplification induced by DNA damage occurs during a prolonged G2 phase and involves ATM.

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Centrosomes as DNA damage regulators

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Centrosomes split in the presence of impaired DNA integrity during mitosis

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Short term cyclin D1 overexpression induces centrosome amplification, mitotic spindle abnormalities, and aneuploidy.

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The oncogenic potential of Kaposi's sarcoma-associated herpesvirus cyclin is exposed by p53 loss in vitro and in vivo

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p16(INK4a) prevents centrosome dysfunction and genomic instability in primary cells

21 January 2018

1 reference

Small lymphocytic lymphoma, marginal zone B-cell lymphoma, and mantle cell lymphoma exhibit distinct gene-expression profiles allowing molecular diagnosis

21 January 2018

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Gene expression profiling of mantle cell lymphoma cells reveals aberrant expression of genes from the PI3K-AKT, WNT and TGFbeta signalling pathways.

21 January 2018

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Microarray-based screening for molecular markers in medulloblastoma revealed STK15 as independent predictor for survival.

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Pericentrin, a highly conserved centrosome protein involved in microtubule organization

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Significance analysis of microarrays applied to the ionizing radiation response

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Diagnosis of multiple cancer types by shrunken centroids of gene expression

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Evidence for distinct pathomechanisms in B-cell chronic lymphocytic leukemia and mantle cell lymphoma by quantitative expression analysis of cell cycle and apoptosis-associated genes

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A new mathematical model for relative quantification in real-time RT-PCR

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Centrosome aberrations in chronic myeloid leukemia correlate with stage of disease and chromosomal instability

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Clinical implication of centrosome amplification in plasma cell neoplasm

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Excessive centrosome abnormalities without ongoing numerical chromosome instability in a Burkitt's lymphoma

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Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cycle

21 January 2018

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Pericentrin and gamma-tubulin form a protein complex and are organized into a novel lattice at the centrosome

21 January 2018

1 reference

Calcium, calmodulin, and CaMKII requirement for initiation of centrosome duplication in Xenopus egg extracts

21 January 2018

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Function and regulation of cullin-RING ubiquitin ligases

21 January 2018

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Dynamic association of proteasomal machinery with the centrosome

21 January 2018

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The centrosome in human genetic disease

21 January 2018

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Cyclin D dysregulation: an early and unifying pathogenic event in multiple myeloma

21 January 2018

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Mutually exclusive cyclin-dependent kinase 4/cyclin D1 and cyclin-dependent kinase 6/cyclin D2 pairing inactivates retinoblastoma protein and promotes cell cycle dysregulation in multiple myeloma

21 January 2018

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The proliferation gene expression signature is a quantitative integrator of oncogenic events that predicts survival in mantle cell lymphoma

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IJC.22404

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15 May 2018

PubMed ID

17236200

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15 May 2018